3PUC.A | TTN – ASTRID

3PUC.A | TTN

PDB ID	3puc
HGNC Gene Label(s)	TTN
Structure Name	atomic resolution structure of titin domain m7
Resolution	0.96Å
Reference	AUTH F.SAUER,M.WILMANNSTITL STRUCTURE OF TITIN M7REF TO BE PUBLISHEDREFN

ExAC Variants

Position	Variant	AA Change	PDB Chain Position	Structure Coordinates
2:179395083	rs367732354	P>R	A:7	(4.51, -11.95, 18.03)
2:179395084	rs567191587	P>S	A:7	(4.51, -11.95, 18.03)
2:179395075		V>F	A:10	(13.65, -8.00, 14.21)
2:179395069		G>R	A:12	(10.51, -1.37, 12.73)
2:179395059		D>V	A:15	(8.25, 8.63, 10.33)
2:179395050		V>A	A:18	(6.74, 8.53, -0.56)
2:179395051		V>L	A:18	(6.74, 8.53, -0.56)
2:179395047	COSM1010130 COSM1010129 COSM1590975 COSM1010128 COSM1010126	S>Y	A:19	(6.79, 11.39, -4.13)
2:179395042		D>H	A:21	(2.33, 10.20, -8.70)
2:179395030		K>E	A:25	(8.67, -0.17, -1.59)
2:179395023		A>V	A:27	(9.22, -3.42, 5.73)
2:179394999	rs369703073	R>Q	A:35	(5.06, -18.20, 11.98)
2:179395000	rs530453291	R>W	A:35	(5.06, -18.20, 11.98)
2:179394993	rs371022420	T>S	A:37	(0.20, -13.71, 10.15)
2:179394977		K>N	A:42	(-4.67, 5.04, 6.20)
2:179394836		T>I	A:48	(-7.57, -5.04, 2.50)
2:179394830	rs373369136	G>A	A:50	(-5.46, -5.01, -3.98)
2:179394827	rs528138560	G>D	A:51	(-4.94, -2.53, -6.44)
2:179394801		G>R	A:60	(9.89, -12.80, 8.84)
2:179394797		G>V	A:61	(9.02, -10.44, 6.66)
2:179394776	rs200716018	K>R	A:68	(-2.19, 6.30, -8.48)
2:179394767		T>S	A:71	(-2.78, 13.57, -0.69)
2:179394752		L>H	A:76	(-1.05, 5.97, 12.04)
2:179394750	rs199663911	Y>H	A:77	(0.25, 3.80, 6.88)
2:179394729	rs369870182	S>A	A:84	(-1.86, -18.34, 18.56)
2:179394707	rs575070622	S>T	A:91	(3.52, 2.39, 13.93)