Assessment of Structural Intolerance and Durability
General Structure Information 2p2r PCBP2 crystal structure of the third kh domain of human poly(c)- binding protein-2 in complex with c-rich strand of human telomeric dna 1.6Å AUTH S.FENN,Z.DU,J.K.LEE,R.TJHEN,R.M.STROUD,T.L.JAMESTITL CRYSTAL STRUCTURE OF THE THIRD KH DOMAIN OF HUMANTITL 2 POLY(C)-BINDING PROTEIN-2 IN COMPLEX WITH A C-RICHTITL 3 STRAND OF HUMAN TELOMERIC DNA AT 1.6 A […]
General Structure Information 2p2r PCBP2 crystal structure of the third kh domain of human poly(c)- binding protein-2 in complex with c-rich strand of human telomeric dna 1.6Å AUTH S.FENN,Z.DU,J.K.LEE,R.TJHEN,R.M.STROUD,T.L.JAMESTITL CRYSTAL STRUCTURE OF THE THIRD KH DOMAIN OF HUMANTITL 2 POLY(C)-BINDING PROTEIN-2 IN COMPLEX WITH A C-RICHTITL 3 STRAND OF HUMAN TELOMERIC DNA AT 1.6 A […]
General Structure Information 4dpg KARS crystal structure of human lysrs: p38/aimp2 complex i 2.84Å AUTH Y.OFIR-BIRIN,P.FANG,S.P.BENNETT,H.M.ZHANG,J.WANG,I.RACHMIN,AUTH 2 R.SHAPIRO,J.SONG,A.DAGAN,J.POZO,S.KIM,A.G.MARSHALL,AUTH 3 P.SCHIMMEL,X.L.YANG,H.NECHUSHTAN,E.RAZIN,M.GUOTITL STRUCTURAL SWITCH OF LYSYL-TRNA SYNTHETASE BETWEENTITL 2 TRANSLATION AND TRANSCRIPTION.REF MOL.CELL V. 49 30 2013REFN ISSN 1097-2765PMID 23159739DOI 10.1016/J.MOLCEL.2012.10.010 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 4dpg KARS crystal structure of human lysrs: p38/aimp2 complex i 2.84Å AUTH Y.OFIR-BIRIN,P.FANG,S.P.BENNETT,H.M.ZHANG,J.WANG,I.RACHMIN,AUTH 2 R.SHAPIRO,J.SONG,A.DAGAN,J.POZO,S.KIM,A.G.MARSHALL,AUTH 3 P.SCHIMMEL,X.L.YANG,H.NECHUSHTAN,E.RAZIN,M.GUOTITL STRUCTURAL SWITCH OF LYSYL-TRNA SYNTHETASE BETWEENTITL 2 TRANSLATION AND TRANSCRIPTION.REF MOL.CELL V. 49 30 2013REFN ISSN 1097-2765PMID 23159739DOI 10.1016/J.MOLCEL.2012.10.010 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 4dpg KARS crystal structure of human lysrs: p38/aimp2 complex i 2.84Å AUTH Y.OFIR-BIRIN,P.FANG,S.P.BENNETT,H.M.ZHANG,J.WANG,I.RACHMIN,AUTH 2 R.SHAPIRO,J.SONG,A.DAGAN,J.POZO,S.KIM,A.G.MARSHALL,AUTH 3 P.SCHIMMEL,X.L.YANG,H.NECHUSHTAN,E.RAZIN,M.GUOTITL STRUCTURAL SWITCH OF LYSYL-TRNA SYNTHETASE BETWEENTITL 2 TRANSLATION AND TRANSCRIPTION.REF MOL.CELL V. 49 30 2013REFN ISSN 1097-2765PMID 23159739DOI 10.1016/J.MOLCEL.2012.10.010 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 4a0l CUL4B structure of ddb1-ddb2-cul4b-rbx1 bound to a 12 bp abasic site containing dna-duplex 7.4Å AUTH E.S.FISCHER,A.SCRIMA,K.BOHM,S.MATSUMOTO,G.M.LINGARAJU,AUTH 2 M.FATY,T.YASUDA,S.CAVADINI,M.WAKASUGI,F.HANAOKA,S.IWAI,AUTH 3 H.GUT,K.SUGASAWA,N.H.THOMATITL THE MOLECULAR BASIS OF CRL4(DDB2/CSA) UBIQUITIN LIGASETITL 2 ARCHITECTURE, TARGETING, AND ACTIVATION.REF CELL(CAMBRIDGE,MASS.) V. 147 1024 2011REFN ISSN 0092-8674PMID 22118460DOI 10.1016/J.CELL.2011.10.035 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons […]
General Structure Information 4itj RIPK1 crystal structure of rip1 kinase in complex with necrostatin-4 1.8Å AUTH T.XIE,W.PENG,Y.LIU,C.YAN,J.MAKI,A.DEGTEREV,J.YUAN,Y.SHITITL STRUCTURAL BASIS OF RIP1 INHIBITION BY NECROSTATINS.REF STRUCTURE V. 21 493 2013REFN ISSN 0969-2126PMID 23473668DOI 10.1016/J.STR.2013.01.016 Variant Set Distributions Mapped Variants
General Structure Information 4itj RIPK1 crystal structure of rip1 kinase in complex with necrostatin-4 1.8Å AUTH T.XIE,W.PENG,Y.LIU,C.YAN,J.MAKI,A.DEGTEREV,J.YUAN,Y.SHITITL STRUCTURAL BASIS OF RIP1 INHIBITION BY NECROSTATINS.REF STRUCTURE V. 21 493 2013REFN ISSN 0969-2126PMID 23473668DOI 10.1016/J.STR.2013.01.016 Variant Set Distributions Mapped Variants
General Structure Information 4itj RIPK1 crystal structure of rip1 kinase in complex with necrostatin-4 1.8Å AUTH T.XIE,W.PENG,Y.LIU,C.YAN,J.MAKI,A.DEGTEREV,J.YUAN,Y.SHITITL STRUCTURAL BASIS OF RIP1 INHIBITION BY NECROSTATINS.REF STRUCTURE V. 21 493 2013REFN ISSN 0969-2126PMID 23473668DOI 10.1016/J.STR.2013.01.016 Variant Set Distributions Mapped Variants
General Structure Information 4dck SCN5A crystal structure of the c-terminus of voltage-gated sodium channel in complex with fgf13 and cam 2.2Å AUTH C.WANG,B.C.CHUNG,H.YAN,S.Y.LEE,G.S.PITTTITL CRYSTAL STRUCTURE OF THE TERNARY COMPLEX OF A NAV C-TERMINALTITL 2 DOMAIN, A FIBROBLAST GROWTH FACTOR HOMOLOGOUS FACTOR, ANDTITL 3 CALMODULIN.REF STRUCTURE V. 20 1167 2012REFN ISSN 0969-2126PMID 22705208DOI 10.1016/J.STR.2012.05.001 Variant Set […]