General Structure Information
| PDB ID | 4itj |
| HGNC Gene Label(s) | RIPK1 |
| Structure Name | crystal structure of rip1 kinase in complex with necrostatin-4 |
| Resolution | 1.8Å |
| Reference | AUTH T.XIE,W.PENG,Y.LIU,C.YAN,J.MAKI,A.DEGTEREV,J.YUAN,Y.SHITITL STRUCTURAL BASIS OF RIP1 INHIBITION BY NECROSTATINS.REF STRUCTURE V. 21 493 2013REFN ISSN 0969-2126PMID 23473668DOI 10.1016/J.STR.2013.01.016 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 276 |
| Number Of SNVs | 75 |
| Number Of Permutations | 31386 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.027 |
| p-value | 0.638 |