Assessment of Structural Intolerance and Durability
General Structure Information 3w98 HIST1H3H crystal structure of human nucleosome core particle lacking h3.1 n- terminal region 3.42Å AUTH W.IWASAKI,Y.MIYA,N.HORIKOSHI,A.OSAKABE,H.TAGUCHI,AUTH 2 H.TACHIWANA,T.SHIBATA,W.KAGAWA,H.KURUMIZAKATITL CONTRIBUTION OF HISTONE N-TERMINAL TAILS TO THE STRUCTURETITL 2 AND STABILITY OF NUCLEOSOMESREF FEBS OPEN BIO V. 3 363 2013REFN ESSN 2211-5463PMID 24251097DOI 10.1016/J.FOB.2013.08.007 Variant Set Distributions Ripley’s K Analysis Plots Variant Set […]
General Structure Information 3w98 HIST1H3J crystal structure of human nucleosome core particle lacking h3.1 n- terminal region 3.42Å AUTH W.IWASAKI,Y.MIYA,N.HORIKOSHI,A.OSAKABE,H.TAGUCHI,AUTH 2 H.TACHIWANA,T.SHIBATA,W.KAGAWA,H.KURUMIZAKATITL CONTRIBUTION OF HISTONE N-TERMINAL TAILS TO THE STRUCTURETITL 2 AND STABILITY OF NUCLEOSOMESREF FEBS OPEN BIO V. 3 363 2013REFN ESSN 2211-5463PMID 24251097DOI 10.1016/J.FOB.2013.08.007 Variant Set Distributions Ripley’s K Analysis Plots Variant Set […]
General Structure Information 3w98 HIST1H3D crystal structure of human nucleosome core particle lacking h3.1 n- terminal region 3.42Å AUTH W.IWASAKI,Y.MIYA,N.HORIKOSHI,A.OSAKABE,H.TAGUCHI,AUTH 2 H.TACHIWANA,T.SHIBATA,W.KAGAWA,H.KURUMIZAKATITL CONTRIBUTION OF HISTONE N-TERMINAL TAILS TO THE STRUCTURETITL 2 AND STABILITY OF NUCLEOSOMESREF FEBS OPEN BIO V. 3 363 2013REFN ESSN 2211-5463PMID 24251097DOI 10.1016/J.FOB.2013.08.007 Variant Set Distributions Ripley’s K Analysis Plots Variant Set […]
General Structure Information 3ex7 MAGOH the crystal structure of ejc in its transition state 2.3Å AUTH K.H.NIELSEN,H.CHAMIEH,C.B.ANDERSEN,F.FREDSLUND,AUTH 2 K.HAMBORG,H.LE HIR,G.R.ANDERSENTITL MECHANISM OF ATP TURNOVER INHIBITION IN THE EJCREF RNA V. 15 67 2009REFN ISSN 1355-8382PMID 19033377DOI 10.1261/RNA.1283109 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 1w8m PPIA enzymatic and structural characterisation of non peptide ligand cyclophilin complexes 1.65Å AUTH G.KONTOPIDIS,P.TAYLOR,M.WALKINSHAWTITL ENZYMATIC AND STRUCTURAL CHARACTERIZATION OFTITL 2 NON-PEPTIDE LIGAND-CYCLOPHILIN COMPLEXESREF ACTA CRYSTALLOGR.,SECT.D V. 60 479 2004REFN ISSN 0907-4449PMID 14993672DOI 10.1107/S0907444904000174 Variant Set Distributions Mapped Variants
General Structure Information 2i38 SRSF3 solution structure of the rrm of srp20 -1.0Å AUTH Y.HARGOUS,G.M.HAUTBERGUE,A.M.TINTARU,L.SKRISOVSKA,AUTH 2 A.P.GOLOVANOV,J.STEVENIN,L.Y.LIAN,S.A.WILSON,AUTH 3 F.H.ALLAINTITL MOLECULAR BASIS OF RNA RECOGNITION AND TAP BINDINGTITL 2 BY THE SR PROTEINS SRP20 AND 9G8.REF EMBO J. V. 25 5126 2006REFN ISSN 0261-4189PMID 17036044DOI 10.1038/SJ.EMBOJ.7601385 Variant Set Distributions Mapped Variants
General Structure Information 2ast SKP1 crystal structure of skp1-skp2-cks1 in complex with a p27 peptide 2.3Å AUTH B.HAO,N.ZHENG,B.A.SCHULMAN,G.WU,J.J.MILLER,M.PAGANO,AUTH 2 N.P.PAVLETICHTITL STRUCTURAL BASIS OF THE CKS1-DEPENDENT RECOGNITION OFTITL 2 P27(KIP1) BY THE SCF(SKP2) UBIQUITIN LIGASE.REF MOL.CELL V. 20 9 2005REFN ISSN 1097-2765PMID 16209941DOI 10.1016/J.MOLCEL.2005.09.003 Variant Set Distributions Mapped Variants
General Structure Information 1jsu CDKN1B p27(kip1)/cyclin a/cdk2 complex 2.3Å AUTH A.A.RUSSO,P.D.JEFFREY,A.K.PATTEN,J.MASSAGUE,AUTH 2 N.P.PAVLETICHTITL CRYSTAL STRUCTURE OF THE P27KIP1TITL 2 CYCLIN-DEPENDENT-KINASE INHIBITOR BOUND TO THETITL 3 CYCLIN A-CDK2 COMPLEX.REF NATURE V. 382 325 1996REFN ISSN 0028-0836PMID 8684460DOI 10.1038/382325A0 Variant Set Distributions Mapped Variants
General Structure Information 2gl8 RXRG human retinoic acid receptor rxr-gamma ligand-binding domain 2.4Å AUTH A.SCHUETZ,J.R.MIN,P.LOPPNAU,J.WEIGELT,M.SUNDSTROM,AUTH 2 A.M.EDWARDS,C.H.ARROWSMITH,A.BOCHKAREV,A.N.PLOTNIKOVTITL THE CRYSTAL STRUCTURE OF HUMAN RETINOIC ACID RECEPTORTITL 2 RXR-GAMMA LIGAND-BINDING DOMAIN.REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3sxs BMX crystal structure of bmx non-receptor tyrosine kinase complexed with pp2 1.89Å AUTH J.MUCKELBAUER,J.S.SACK,N.AHMED,J.BURKE,C.Y.CHANG,M.GAO,AUTH 2 J.TINO,D.XIE,A.J.TEBBENTITL X-RAY CRYSTAL STRUCTURE OF BONE MARROW KINASE IN THE XTITL 2 CHROMOSOME: A TEC FAMILY KINASE.REF CHEM.BIOL.DRUG DES. V. 78 739 2011REFN ISSN 1747-0277PMID 21883956DOI 10.1111/J.1747-0285.2011.01230.X Variant Set Distributions Ripley’s K Analysis Plots Variant Set […]