General Structure Information
| PDB ID | 3sxs |
| HGNC Gene Label(s) | BMX |
| Structure Name | crystal structure of bmx non-receptor tyrosine kinase complexed with pp2 |
| Resolution | 1.89Å |
| Reference | AUTH J.MUCKELBAUER,J.S.SACK,N.AHMED,J.BURKE,C.Y.CHANG,M.GAO,AUTH 2 J.TINO,D.XIE,A.J.TEBBENTITL X-RAY CRYSTAL STRUCTURE OF BONE MARROW KINASE IN THE XTITL 2 CHROMOSOME: A TEC FAMILY KINASE.REF CHEM.BIOL.DRUG DES. V. 78 739 2011REFN ISSN 1747-0277PMID 21883956DOI 10.1111/J.1747-0285.2011.01230.X |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 261 |
| Number Of SNVs | 39 |
| Number Of Permutations | 5564 |
| Optimal Distance Threshold | 17.0 |
| K Statistic | 0.227 |
| p-value | 0.534 |
COSMIC
| Number Of Residues | 261 |
| Number Of SNVs | 5 |
| Number Of Permutations | 905 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | 0.3 |
| p-value | 0.774 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 39 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 18.0 |
| K Statistic | -0.274 |
| p-value | 0.387 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
