Assessment of Structural Intolerance and Durability
General Structure Information 2kkq MYOT solution nmr structure of the ig-like c2-type 2 domain of human myotilin. northeast structural genomics target hr3158. -1.0Å AUTH P.ROSSI,G.T.MONTELIONETITL SOLUTION NMR STRUCTURE OF THE IG-LIKE C2-TYPE 2TITL 2 DOMAIN OF HUMAN MYOTILIN. NORTHEAST STRUCTURALTITL 3 GENOMICS TARGET HR3158.REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2box EMR2 egf domains 1,2,5 of human emr2, a 7-tm immune system molecule, in complex with strontium. 2.5Å AUTH R.J.M.ABBOTT,I.SPENDLOVE,P.ROVERSI,H.FITZGIBBON,V.KNOTT,AUTH 2 P.TERIETE,J.M.MCDONNELL,P.A.HANDFORD,S.M.LEATITL STRUCTURAL AND FUNCTIONAL CHARACTERIZATION OF A NOVEL TTITL 2 CELL RECEPTOR CO-REGULATORY PROTEIN COMPLEX, CD97-CD55.REF J.BIOL.CHEM. V. 282 22023 2007REFN ISSN 0021-9258PMID 17449467DOI 10.1074/JBC.M702588200 Variant Set Distributions Ripley’s K Analysis […]
General Structure Information 3fn3 CD274 dimeric structure of pd-l1 2.7Å AUTH Y.CHEN,P.LIU,F.GAO,H.CHENG,J.QI,G.F.GAOTITL A DIMERIC STRUCTURE OF PD-L1: FUNCTIONAL UNITS ORTITL 2 EVOLUTIONARY RELICS?REF PROTEIN CELL V. 1 153 2010REFN ISSN 1674-800XPMID 21203985DOI 10.1007/S13238-010-0022-1 Variant Set Distributions Mapped Variants
General Structure Information 3krm IGF2BP1 imp1 kh34 2.75Å AUTH J.A.CHAO,Y.PATSKOVSKY,V.PATEL,M.LEVY,S.C.ALMO,AUTH 2 R.H.SINGERTITL ZBP1 RECOGNITION OF BETA-ACTIN ZIPCODE INDUCES RNATITL 2 LOOPING.REF GENES DEV. V. 24 148 2010REFN ISSN 0890-9369PMID 20080952DOI 10.1101/GAD.1862910 Variant Set Distributions Mapped Variants
General Structure Information 3ffl ANAPC7 crystal structure of the n-terminal domain of anaphase-promoting complex subunit 7 2.5Å AUTH D.HAN,K.KIM,Y.KIM,Y.KANG,Y.KIMTITL CRYSTAL STRUCTURE OF THE N-TERMINAL DOMAIN OFTITL 2 ANAPHASE-PROMOTING COMPLEX SUBUNIT 7REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 4f9b DBF4 human cdc7 kinase in complex with dbf4 and pha767491 2.5Å AUTH S.HUGHES,F.ELUSTONDO,A.DI FONZO,F.G.LEROUX,A.C.WONG,AUTH 2 A.P.SNIJDERS,S.J.MATTHEWS,P.CHEREPANOVTITL CRYSTAL STRUCTURE OF HUMAN CDC7 KINASE IN COMPLEX WITH ITSTITL 2 ACTIVATOR DBF4.REF NAT.STRUCT.MOL.BIOL. V. 19 1101 2012REFN ISSN 1545-9993PMID 23064647DOI 10.1038/NSMB.2404 Variant Set Distributions Mapped Variants
General Structure Information 4i2x SIRPG crystal structure of signal regulatory protein gamma (sirp-gamma) in complex with fabox117 2.48Å AUTH J.E.NETTLESHIP,J.REN,D.J.SCOTT,N.RAHMAN,D.HATHERLEY,Y.ZHAO,AUTH 2 D.I.STUART,A.N.BARCLAY,R.J.OWENSTITL CRYSTAL STRUCTURE OF SIGNAL REGULATORY PROTEIN GAMMA (SIRPTITL 2 GAMMA) IN COMPLEX WITH AN ANTIBODY FAB FRAGMENT.REF BMC STRUCT.BIOL. V. 13 13 2013REFN ESSN 1472-6807PMID 23826770DOI 10.1186/1472-6807-13-13 Variant Set Distributions Ripley’s K Analysis […]
General Structure Information 2q87 CD300A the crystal structure of the human irp60 ectodomain 1.7Å AUTH N.DIMASI,J.A.MARQUEZTITL THE CRYSTAL STRUCTURE OF IRP60 ECTODOMAINREF TO BE PUBLISHED 2007REFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3l82 FBXO4 x-ray crystal structure of trf1 and fbx4 complex 2.4Å AUTH Z.ZENG,W.WANG,Y.YANG,Y.CHEN,X.YANG,J.A.DIEHL,X.LIU,M.LEITITL STRUCTURAL BASIS OF SELECTIVE UBIQUITINATION OF TRF1 BYTITL 2 SCF(FBX4)REF DEV.CELL V. 18 214 2010REFN ISSN 1534-5807PMID 20159592DOI 10.1016/J.DEVCEL.2010.01.007 Variant Set Distributions Mapped Variants
General Structure Information 4afl ING4 the crystal structure of the ing4 dimerization domain reveals the functional organization of the ing family of chromatin binding proteins. 2.28Å AUTH S.CULURGIONI,I.G.MUNOZ,A.MORENO,A.PALACIOS,M.VILLATE,AUTH 2 I.PALMERO,G.MONTOYA,F.J.BLANCOTITL CRYSTAL STRUCTURE OF INHIBITOR OF GROWTH 4 (ING4)TITL 2 DIMERIZATION DOMAIN REVEALS FUNCTIONAL ORGANIZATION OF INGTITL 3 FAMILY OF CHROMATIN-BINDING PROTEINS.REF J.BIOL.CHEM. V. 287 10876 […]