Assessment of Structural Intolerance and Durability
General Structure Information 3zyj NTNG1 netring1 in complex with ngl1 3.25Å AUTH E.SEIRADAKE,C.H.COLES,P.V.PERESTENKO,K.HARLOS,AUTH 2 R.A.J.MCILHINNEY,A.R.ARICESCU,E.Y.JONESTITL STRUCTURAL BASIS FOR CELL SURFACE PATTERNINGTITL 2 THROUGH NETRING-NGL INTERACTIONS.REF EMBO J. V. 30 4479 2011REFN ISSN 0261-4189PMID 21946559DOI 10.1038/EMBOJ.2011.346 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 4dzo MAD1L1 structure of human mad1 c-terminal domain reveals its involvement in kinetochore targeting 1.76Å AUTH S.KIM,H.SUN,D.R.TOMCHICK,H.YU,X.LUOTITL STRUCTURE OF HUMAN MAD1 C-TERMINAL DOMAIN REVEALS ITSTITL 2 INVOLVEMENT IN KINETOCHORE TARGETING.REF PROC.NATL.ACAD.SCI.USA V. 109 6549 2012REFN ISSN 0027-8424PMID 22493223DOI 10.1073/PNAS.1118210109 Variant Set Distributions Mapped Variants
General Structure Information 3h6n PLXND1 crystal structure of the ubiquitin-like domain of plexin d1 2.0Å AUTH Y.TONG,L.NEDYALKOVA,W.TEMPEL,F.MACKENZIE,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,C.BOUNTRA,J.WEIGELT,AUTH 3 A.BOCHKAREV,M.BUCK,H.PARKTITL CRYSTAL STRUCTURE OF THE UBIQUITIN-LIKE DOMAIN OFTITL 2 PLEXIN D1REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3qor NUDC crystal structure of human nuclear migration protein nudc 1.75Å AUTH M.ZHENG,T.CIERPICKI,A.J.BURDETTE,D.UTEPBERGENOV,P.L.JANCZYK,AUTH 2 U.DEREWENDA,P.T.STUKENBERG,K.A.CALDWELL,Z.S.DEREWENDATITL STRUCTURAL FEATURES AND CHAPERONE ACTIVITY OF THE NUDCTITL 2 PROTEIN FAMILY.REF J.MOL.BIOL. V. 409 722 2011REFN ISSN 0022-2836PMID 21530541DOI 10.1016/J.JMB.2011.04.018 Variant Set Distributions Mapped Variants
General Structure Information 4hlj ROBO1 axon guidance receptor 1.8Å AUTH R.BARAK,Y.OPATOWSKYTITL CRYSTAL STRUCTURE OF AXON GUIDANCE RECEPTORREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2eo9 ROBO1 solution structure of the fifth ig-like domain from human roundabout homo1 -1.0Å AUTH K.NAGASHIMA,M.YOSHIDA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FIFTH IG-LIKE DOMAINTITL 2 FROM HUMAN ROUNDABOUT HOMO1REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1y2o BAIAP2 structure of n-terminal domain irsp53/baiap2 2.2Å AUTH T.H.MILLARD,G.BOMPARD,M.-Y.HEUNG,T.R.DAFFORN,AUTH 2 D.J.SCOTT,L.M.MACHESKY,K.FUTTERERTITL STRUCTURAL BASIS OF FILOPODIA FORMATION INDUCED BYTITL 2 THE IRSP53/MIM HOMOLOGY DOMAIN OF HUMAN IRSP53REF EMBO J. V. 24 240 2005REFN ISSN 0261-4189PMID 15635447DOI 10.1038/SJ.EMBOJ.7600535 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2ns2 SPIN1 crystal structure of spindlin1 2.2Å AUTH Q.ZHAO,L.QIN,F.JIANG,B.WU,W.YUE,F.XU,Z.RONG,H.YUAN,AUTH 2 X.XIE,Y.GAO,C.BAI,M.BARTLAM,X.PEI,Z.RAOTITL STRUCTURE OF HUMAN SPINDLIN1. TANDEM TUDOR-LIKETITL 2 DOMAINS FOR CELL CYCLE REGULATIONREF J.BIOL.CHEM. V. 282 647 2007REFN ISSN 0021-9258PMID 17082182DOI 10.1074/JBC.M604029200 Variant Set Distributions Mapped Variants
General Structure Information 1tvg HSPB11 x-ray structure of human pp25 gene product, hspc034. northeast structural genomics target hr1958. 1.6Å AUTH T.A.RAMELOT,S.RAMAN,A.P.KUZIN,R.XIAO,L.C.MA,AUTH 2 T.B.ACTON,J.F.HUNT,G.T.MONTELIONE,D.BAKER,AUTH 3 M.A.KENNEDYTITL IMPROVING NMR PROTEIN STRUCTURE QUALITY BY ROSETTATITL 2 REFINEMENT: A MOLECULAR REPLACEMENT STUDY.REF PROTEINS V. 75 147 2009REFN ISSN 0887-3585PMID 18816799DOI 10.1002/PROT.22229 Variant Set Distributions Mapped Variants
General Structure Information 2crm FNDC3A solution structure of the forth fniii domain of human -1.0Å AUTH K.IZUMI,F.HAYASHI,M.YOSHIDA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FORTH FNIII DOMAIN OFTITL 2 HUMANREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants