General Structure Information
| PDB ID | 1y2o |
| HGNC Gene Label(s) | BAIAP2 |
| Structure Name | structure of n-terminal domain irsp53/baiap2 |
| Resolution | 2.2Å |
| Reference | AUTH T.H.MILLARD,G.BOMPARD,M.-Y.HEUNG,T.R.DAFFORN,AUTH 2 D.J.SCOTT,L.M.MACHESKY,K.FUTTERERTITL STRUCTURAL BASIS OF FILOPODIA FORMATION INDUCED BYTITL 2 THE IRSP53/MIM HOMOLOGY DOMAIN OF HUMAN IRSP53REF EMBO J. V. 24 240 2005REFN ISSN 0261-4189PMID 15635447DOI 10.1038/SJ.EMBOJ.7600535 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 240 |
| Number Of SNVs | 47 |
| Number Of Permutations | 34537 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.078 |
| p-value | 0.696 |
COSMIC
| Number Of Residues | 240 |
| Number Of SNVs | 4 |
| Number Of Permutations | 1565 |
| Optimal Distance Threshold | 49.0 |
| K Statistic | 0.333 |
| p-value | 0.557 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 47 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 65.0 |
| K Statistic | -0.404 |
| p-value | 0.215 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
