Assessment of Structural Intolerance and Durability
General Structure Information 3pd7 TOPBP1 crystal structure of the sixth brct domain of human topbp1 1.26Å AUTH J.LEE,C.XU,G.CUI,J.R.THOMPSON,G.MERTITL CRYSTAL STRUCTURE OF THE SIXTH BRCT DOMAIN OF HUMAN TOPBP1REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1uey NRCAM solution structure of the first fibronectin type iii domain of human kiaa0343 protein -1.0Å AUTH C.ZHAO,T.KIGAWA,Y.MUTO,S.KOSHIBA,N.TOCHIO,M.INOUE,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FIRST FIBRONECTIN TYPETITL 2 III DOMAIN OF HUMAN KIAA0343 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3ec8 RADIL the crystal structure of the ra domain of flj10324 (radil) 2.6Å AUTH M.WISNIEWSKA,L.LEHTIO,J.ANDERSSON,C.H.ARROWSMITH,R.COLLINS,AUTH 2 L.G.DAHLGREN,A.M.EDWARDS,S.FLODIN,A.FLORES,S.GRASLUND,AUTH 3 M.HAMMARSTROM,A.JOHANSSON,I.JOHANSSON,T.KARLBERG,AUTH 4 T.KOTENYOVA,M.MOCHE,M.E.NILSSON,P.NORDLUND,T.NYMAN,K.OLESEN,AUTH 5 C.PERSSON,J.SAGEMARK,H.SCHUELER,A.G.THORSELL,L.TRESAUGUES,AUTH 6 S.VAN DEN BERG,J.WEIGELT,M.WELIN,M.WIKSTROM,H.BERGLUNDTITL THE CRYSTAL STRUCTURE OF THE RA DOMAIN OF FLJ10324 (RADIL)REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity […]
General Structure Information 3c9q WDYHV1 crystal structure of the uncharacterized human protein c8orf32 with bound peptide 1.5Å AUTH E.BITTO,C.A.BINGMAN,J.G.MCCOY,G.E.WESENBERG,G.N.PHILLIPS JR.TITL CRYSTAL STRUCTURE OF THE UNCHARACTERIZED HUMAN PROTEINTITL 2 C8ORF32 WITH BOUND PEPTIDE.REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2lgx FERMT2 nmr structure for kindle-2 n-terminus -1.0Å AUTH H.D.PERERA,Y.Q.MA,J.YANG,J.HIRBAWI,E.F.PLOW,J.QINTITL MEMBRANE BINDING OF THE N-TERMINAL UBIQUITIN-LIKE DOMAIN OFTITL 2 KINDLIN-2 IS CRUCIAL FOR ITS REGULATION OF INTEGRINTITL 3 ACTIVATION.REF STRUCTURE V. 19 1664 2011REFN ISSN 0969-2126PMID 22078565DOI 10.1016/J.STR.2011.08.012 Variant Set Distributions Mapped Variants
General Structure Information 1x5h NEO1 the solution structure of the third fibronectin type iii domain of human neogenin -1.0Å AUTH N.TOCHIO,A.SASAGAWA,S.KOSHIBA,M.INOUE,T.KIGAWA,AUTH 2 S.YOKOYAMATITL THE SOLUTION STRUCTURE OF THE THIRD FIBRONECTINTITL 2 TYPE III DOMAIN OF HUMAN NEOGENINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2xoc CHFR c-terminal cysteine-rich domain of human chfr bound to madpr 1.89Å AUTH J.OBEROI,M.W.RICHARDS,S.CRUMPLER,N.BROWN,J.BLAGG,AUTH 2 R.BAYLISSTITL STRUCTURAL BASIS OF POLY(ADP-RIBOSE) RECOGNITIONTITL 2 BY THE MULTIZINC BINDING DOMAIN OF CHECKPOINT WITHTITL 3 FORKHEAD-ASSOCIATED AND RING DOMAINS (CHFR).REF J.BIOL.CHEM. V. 285 39348 2010REFN ISSN 0021-9258PMID 20880844DOI 10.1074/JBC.M110.159855 Variant Set Distributions Ripley’s K Analysis Plots […]
General Structure Information 3fdw SYTL4 crystal structure of a c2 domain from human synaptotagmin- like protein 4 2.2Å AUTH J.B.BONANNO,M.RUTTER,K.T.BAIN,S.MILLER,R.ROMERO,AUTH 2 S.WASSERMAN,J.M.SAUDER,S.K.BURLEY,S.C.ALMOTITL CRYSTAL STRUCTURE OF A C2 DOMAIN FROM HUMANTITL 2 SYNAPTOTAGMIN-LIKE PROTEIN 4REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3r0n PVRL2 crystal structure of the immunoglobulin variable domain of nectin-2 1.3Å AUTH D.SAMANTA,U.A.RAMAGOPAL,R.RUBINSTEIN,V.VIGDOROVICH,AUTH 2 S.G.NATHENSON,S.C.ALMOTITL STRUCTURE OF NECTIN-2 REVEALS DETERMINANTS OF HOMOPHILIC ANDTITL 2 HETEROPHILIC INTERACTIONS THAT CONTROL CELL-CELL ADHESION.REF PROC.NATL.ACAD.SCI.USA V. 109 14836 2012REFN ISSN 0027-8424PMID 22927415DOI 10.1073/PNAS.1212912109 Variant Set Distributions Mapped Variants
General Structure Information 3zyg NTNG2 netring2 lam and egf1 domains 2.2Å AUTH E.SEIRADAKE,C.H.COLES,P.V.PERESTENKO,K.HARLOS,AUTH 2 R.A.J.MCILHINNEY,A.R.ARICESCU,E.Y.JONESTITL STRUCTURAL BASIS FOR CELL SURFACE PATTERNINGTITL 2 THROUGH NETRING-NGL INTERACTIONS.REF EMBO J. V. 30 4479 2011REFN ISSN 0261-4189PMID 21946559DOI 10.1038/EMBOJ.2011.346 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants