General Structure Information
| PDB ID | 2xoc |
| HGNC Gene Label(s) | CHFR |
| Structure Name | c-terminal cysteine-rich domain of human chfr bound to madpr |
| Resolution | 1.89Å |
| Reference | AUTH J.OBEROI,M.W.RICHARDS,S.CRUMPLER,N.BROWN,J.BLAGG,AUTH 2 R.BAYLISSTITL STRUCTURAL BASIS OF POLY(ADP-RIBOSE) RECOGNITIONTITL 2 BY THE MULTIZINC BINDING DOMAIN OF CHECKPOINT WITHTITL 3 FORKHEAD-ASSOCIATED AND RING DOMAINS (CHFR).REF J.BIOL.CHEM. V. 285 39348 2010REFN ISSN 0021-9258PMID 20880844DOI 10.1074/JBC.M110.159855 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 213 |
| Number Of SNVs | 47 |
| Number Of Permutations | 36486 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.026 |
| p-value | 0.83 |
COSMIC
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 47 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 20.0 |
| K Statistic | -0.333 |
| p-value | 0.349 |