Assessment of Structural Intolerance and Durability
General Structure Information 1wf6 TOPBP1 the third brca1 c-terminus (brct) domain of similar to s.pombe rad4+/cut5+ product -1.0Å AUTH T.NAGASHIMA,F.HAYASHI,S.YOKOYAMATITL THE THIRD BRCA1 C-TERMINUS (BRCT) DOMAIN OFTITL 2 SIMILAR TO S.POMBE RAD4+/CUT5+ PRODUCTREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3tdu DCUN1D1 n-terminal acetylation acts as an avidity enhancer within an interconnected multiprotein complex: structure of a human cul1whb- dcn1p-acetylated ubc12n complex 1.5Å AUTH D.C.SCOTT,J.K.MONDA,E.J.BENNETT,J.W.HARPER,B.A.SCHULMANTITL N-TERMINAL ACETYLATION ACTS AS AN AVIDITY ENHANCER WITHIN ANTITL 2 INTERCONNECTED MULTIPROTEIN COMPLEX.REF SCIENCE V. 334 674 2011REFN ISSN 0036-8075PMID 21940857DOI 10.1126/SCIENCE.1209307 Variant Set Distributions Mapped Variants
General Structure Information 2l80 USP13 solution structure of the zinc finger domain of usp13 -1.0Å AUTH Y.ZHANG,A.SONG,C.ZHOU,Z.ZHOU,H.HUTITL BIOCHEMICAL CHARACTERIZATION OF THE UBIQUITIN RECEPTORS INTITL 2 USP13 REVEALS DIFFERENT CATALYTIC ACTIVATION OFTITL 3 DEUBIQUITINATION FROM ITS ANALOGUE USP5REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 4ido ATL1 human atlastin-1 1-446, c-his6, gdpalf4- 2.09Å AUTH L.J.BYRNES,A.SINGH,K.SZETO,N.M.BENVIN,J.P.ODONNELL,AUTH 2 W.R.ZIPFEL,H.SONDERMANNTITL STRUCTURAL BASIS FOR CONFORMATIONAL SWITCHING AND GTPTITL 2 LOADING OF THE LARGE G PROTEIN ATLASTIN.REF EMBO J. V. 32 369 2013REFN ISSN 0261-4189PMID 23334294DOI 10.1038/EMBOJ.2012.353 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 1x5g NEO1 the solution structure of the second fibronectin type iii domain of human neogenin -1.0Å AUTH N.TOCHIO,S.KOSHIBA,M.INOUE,T.KIGAWA,S.YOKOYAMATITL THE SOLUTION STRUCTURE OF THE SECOND FIBRONECTINTITL 2 TYPE III DOMAIN OF HUMAN NEOGENINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 4fq3 TNPO1 crystal structure of transportin/fus-nls 3.0Å AUTH W.GONG,C.NIU,M.JIA,F.GAOTITL CRYSTAL STRUCTURE OF TRANSPORTIN/FUS-NLSREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3m66 MTERFD1 crystal structure of human mitochondrial transcription termination factor 3 1.6Å AUTH H.SPAHR,T.SAMUELSSON,B.M.HALLBERG,C.M.GUSTAFSSONTITL STRUCTURE OF MITOCHONDRIAL TRANSCRIPTION TERMINATION FACTORTITL 2 3 REVEALS A NOVEL NUCLEIC ACID-BINDING DOMAIN.REF BIOCHEM.BIOPHYS.RES.COMMUN. V. 397 386 2010REFN ISSN 0006-291XPMID 20430012DOI 10.1016/J.BBRC.2010.04.130 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2yuj UFD1L solution structure of human ubiquitin fusion degradation protein 1 homolog ufd1 -1.0Å AUTH K.SAITO,T.TOMIZAWA,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF HUMAN UBIQUITIN FUSIONTITL 2 DEGRADATION PROTEIN 1 HOMOLOG UFD1REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1x5f NEO1 the solution structure of the first fibronectin type iii domain of human neogenin -1.0Å AUTH N.TOCHIO,A.SASAGAWA,S.KOSHIBA,M.INOUE,T.KIGAWA,AUTH 2 S.YOKOYAMATITL THE SOLUTION STRUCTURE OF THE FIRST FIBRONECTINTITL 2 TYPE III DOMAIN OF HUMAN NEOGENINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2pa1 PDLIM2 structure of the pdz domain of human pdlim2 bound to a c-terminal extension from human beta-tropomyosin 1.7Å AUTH J.UPPENBERG,L.SHRESTHA,J.ELKINS,N.BURGESS-BROWN,E.SALAH,AUTH 2 G.BUNKOCZI,E.PAPAGRIGORIOU,A.C.W.PIKE,A.P.TURNBULL,AUTH 3 E.UGOCHUKWU,C.UMEANO,F.VON DELFT,J.WEIGELT,C.H.ARROWSMITH,AUTH 4 A.EDWARDS,M.SUNDSTROM,D.A.DOYLETITL STRUCTURE OF THE PDZ DOMAIN OF HUMAN PDLIM2 BOUND TO ATITL 2 C-TERMINAL EXTENSION FROM HUMAN BETA-TROPOMYOSIN.REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped […]