Assessment of Structural Intolerance and Durability
General Structure Information 1xr0 FRS2 structural basis of snt ptb domain interactions with distinct neurotrophic receptors -1.0Å AUTH C.DHALLUIN,K.S.YAN,O.PLOTNIKOVA,K.W.LEE,L.ZENG,AUTH 2 M.KUTI,S.MUJTABA,M.P.GOLDFARB,M.-M.ZHOUTITL STRUCTURAL BASIS OF SNT PTB DOMAIN INTERACTIONSTITL 2 WITH DISTINCT NEUROTROPHIC RECEPTORSREF MOL.CELL V. 6 921 2000REFN ISSN 1097-2765PMID 11090629DOI 10.1016/S1097-2765(05)00087-0 Variant Set Distributions Mapped Variants
General Structure Information 2gw6 TSEN15 nmr structure of the human trna endonuclease sen15 subunit -1.0Å AUTH J.SONG,J.L.MARKLEYTITL THREE-DIMENSIONAL STRUCTURE DETERMINED FOR ATITL 2 SUBUNIT OF HUMAN TRNA SPLICING ENDONUCLEASETITL 3 (SEN15) REVEALS A NOVEL DIMERIC FOLD.REF J.MOL.BIOL. V. 366 155 2007REFN ISSN 0022-2836PMID 17166513DOI 10.1016/J.JMB.2006.11.024 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons […]
General Structure Information 3le4 DGCR8 crystal structure of the dgcr8 dimerization domain 1.7Å AUTH R.SENTURIA,M.FALLER,S.YIN,J.A.LOO,D.CASCIO,M.R.SAWAYA,AUTH 2 D.HWANG,R.T.CLUBB,F.GUOTITL STRUCTURE OF THE DIMERIZATION DOMAIN OF DIGEORGE CRITICALTITL 2 REGION 8REF PROTEIN SCI. V. 19 1354 2010REFN ISSN 0961-8368PMID 20506313DOI 10.1002/PRO.414 Variant Set Distributions Mapped Variants
General Structure Information 3nnc CELF1 crystal structure of cugbp1 rrm1/2-rna complex 2.2Å AUTH M.TEPLOVA,J.SONG,H.Y.GAW,A.TEPLOV,D.J.PATELTITL STRUCTURAL INSIGHTS INTO RNA RECOGNITION BY THETITL 2 ALTERNATE-SPLICING REGULATOR CUG-BINDING PROTEIN 1.REF STRUCTURE V. 18 1364 2010REFN ISSN 0969-2126PMID 20947024DOI 10.1016/J.STR.2010.06.018 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 1um7 DLG3 solution structure of the third pdz domain of synapse- associated protein 102 -1.0Å AUTH X.-R.QIN,T.NAGASHIMA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE THIRD PDZ DOMAIN OFTITL 2 SYNAPSE-ASSOCIATED PROTEIN 102REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2yt4 DGCR8 crystal structure of human dgcr8 core 2.6Å AUTH S.Y.SOHN,W.J.BAE,J.J.KIM,K.H.YEOM,V.N.KIM,Y.CHOTITL CRYSTAL STRUCTURE OF HUMAN DGCR8 COREREF NAT.STRUCT.MOL.BIOL. V. 14 847 2007REFN ISSN 1545-9993PMID 17704815DOI 10.1038/NSMB1294 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2hh2 KHSRP solution structure of the fourth kh domain of ksrp -1.0Å AUTH M.F.GARCIA-MAYORAL,D.HOLLINGWORTH,L.MASINO,AUTH 2 I.DIAZ-MORENO,G.KELLY,R.GHERZI,C.F.CHOU,C.Y.CHEN,AUTH 3 A.RAMOSTITL THE STRUCTURE OF THE C-TERMINAL KH DOMAINS OF KSRPTITL 2 REVEALS A NONCANONICAL MOTIF IMPORTANT FOR MRNATITL 3 DEGRADATION.REF STRUCTURE V. 15 485 2007REFN ISSN 0969-2126PMID 17437720DOI 10.1016/J.STR.2007.03.006 Variant Set Distributions Mapped Variants
General Structure Information 1j4w FUBP1 complex of the kh3 and kh4 domains of fbp with a single_stranded 29mer dna oligonucleotide from the fuse element of the c-myc oncogene -1.0Å AUTH D.T.BRADDOCK,J.M.LOUIS,J.L.BABER,D.LEVENS,G.M.CLORETITL STRUCTURE AND DYNAMICS OF KH DOMAINS FROM FBPTITL 2 BOUND TO SINGLE-STRANDED DNA.REF NATURE V. 415 1051 2002REFN ISSN 0028-0836PMID 11875576DOI 10.1038/4151051A Variant Set […]
General Structure Information 2m9a ZFP91 solution nmr structure of e3 ubiquitin-protein ligase zfp91 from homo sapiens, northeast structural genomics consortium (nesg) target hr7784a -1.0Å AUTH K.PEDERSON,G.T.MONTELIONE,J.H.PRESTEGARDTITL SOLUTION STRUCTURE OF HR7784AREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2v14 KIF16B kinesin 16b phox-homology domain (kif16b) 2.2Å AUTH N.R.BLATNER,M.I.WILSON,C.LEI,W.HONG,D.MURRAY,AUTH 2 R.L.WILLIAMS,W.CHOTITL THE STRUCTURAL BASIS OF NOVEL ENDOSOME ANCHORINGTITL 2 ACTIVITY OF KIF16B KINESIN.REF EMBO J. V. 26 3709 2007REFN ISSN 0261-4189PMID 17641687DOI 10.1038/SJ.EMBOJ.7601800 Variant Set Distributions Mapped Variants