Assessment of Structural Intolerance and Durability
General Structure Information 2w4r DHX58 crystal structure of the regulatory domain of human lgp2 2.6Å AUTH D.A.PIPPIG,J.C.HELLMUTH,S.CUI,A.KIRCHHOFER,AUTH 2 K.LAMMENS,A.LAMMENS,A.SCHMIDT,S.ROTHENFUSSER,AUTH 3 K.P.HOPFNERTITL THE REGULATORY DOMAIN OF THE RIG-I FAMILY ATPASETITL 2 LGP2 SENSES DOUBLE-STRANDED RNA.REF NUCLEIC ACIDS RES. V. 37 2014 2009REFN ISSN 0305-1048PMID 19208642DOI 10.1093/NAR/GKP059 Variant Set Distributions Mapped Variants
General Structure Information 2dm3 PALLD solution structure of the second ig domain of human palladin -1.0Å AUTH T.NAGASHIMA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE SECOND IG DOMAIN OFTITL 2 HUMAN PALLADINREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2id5 LINGO1 crystal structure of the lingo-1 ectodomain 2.7Å AUTH L.MOSYAK,A.WOOD,B.DWYER,M.BUDDHA,M.JOHNSON,A.AULABAUGH,AUTH 2 X.ZHONG,E.PRESMAN,S.BENARD,K.KELLEHER,J.WILHELM,M.L.STAHL,AUTH 3 R.KRIZ,Y.GAO,Z.CAO,H.P.LING,M.N.PANGALOS,F.S.WALSH,AUTH 4 W.S.SOMERSTITL THE STRUCTURE OF THE LINGO-1 ECTODOMAIN, A MODULE IMPLICATEDTITL 2 IN CENTRAL NERVOUS SYSTEM REPAIR INHIBITION.REF J.BIOL.CHEM. V. 281 36378 2006REFN ISSN 0021-9258PMID 17005555DOI 10.1074/JBC.M607314200 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons […]
General Structure Information 2dme PHF3 solution structure of the tfiis domain ii of human phd finger protein 3 -1.0Å AUTH M.YONEYAMA,N.TOCHIO,S.KOSHIBA,S.WATABE,T.HARADA,AUTH 2 T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE TFIIS DOMAIN II OF HUMANTITL 2 PHD FINGER PROTEIN 3REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 4f7h FERMT2 the crystal structure of kindlin-2 pleckstrin homology domain in free form 1.9Å AUTH Y.LIU,Y.ZHU,S.YE,R.ZHANGTITL CRYSTAL STRUCTURE OF KINDLIN-2 PH DOMAIN REVEALS ATITL 2 CONFORMATIONAL TRANSITION FOR ITS MEMBRANE ANCHORING ANDTITL 3 REGULATION OF INTEGRIN ACTIVATION.REF PROTEIN CELL V. 3 434 2012REFN ISSN 1674-800XPMID 22653426DOI 10.1007/S13238-012-2046-1 Variant Set Distributions Mapped Variants
General Structure Information 2peh RBM17 crystal structure of the uhm domain of human spf45 in complex with sf3b155-ulm5 2.11Å AUTH L.CORSINI,S.BONNA,J.BASQUIN,M.HOTHORN,K.SCHEFFZEK,AUTH 2 J.VALCARCEL,M.SATTLERTITL U2AF-HOMOLOGY MOTIF INTERACTIONS ARE REQUIRED FORTITL 2 ALTERNATIVE SPLICING REGULATION BY SPF45.REF NAT.STRUCT.MOL.BIOL. V. 14 620 2007REFN ISSN 1545-9993PMID 17589525DOI 10.1038/NSMB1260 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped […]
General Structure Information 2vge PPP1R13L crystal structure of the c-terminal region of human iaspp 2.1Å AUTH R.A.ROBINSON,X.LU,E.Y.JONES,C.SIEBOLDTITL BIOCHEMICAL AND STRUCTURAL STUDIES OF ASPPTITL 2 PROTEINS REVEAL DIFFERENTIAL BINDING TO P53, P63TITL 3 AND P73REF STRUCTURE V. 16 259 2008REFN ISSN 0969-2126PMID 18275817DOI 10.1016/J.STR.2007.11.012 Variant Set Distributions Mapped Variants
General Structure Information 2atv RERG the crystal structure of human rerg in the gdp bound state 1.9Å AUTH A.P.TURNBULL,E.SALAH,G.SCHOCH,J.ELKINS,N.BURGESS,O.GILEADI,AUTH 2 F.VON DELFT,J.WEIGELT,A.EDWARDS,C.ARROWSMITH,M.SUNDSTROM,AUTH 3 D.DOYLETITL THE CRYSTAL STRUCTURE OF HUMAN RERG IN THE GDP BOUND STATEREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3f1i STAM human escrt-0 core complex 2.3Å AUTH X.REN,D.P.KLOER,Y.C.KIM,R.GHIRLANDO,L.F.SAIDI,G.HUMMER,AUTH 2 J.H.HURLEYTITL HYBRID STRUCTURAL MODEL OF THE COMPLETE HUMAN ESCRT-0TITL 2 COMPLEX.REF STRUCTURE V. 17 406 2009REFN ISSN 0969-2126PMID 19278655DOI 10.1016/J.STR.2009.01.012 Variant Set Distributions Mapped Variants
General Structure Information 1x6f ZNF462 solution structures of the c2h2 type zinc finger domain of human zinc finger protein 462 -1.0Å AUTH M.SATO,K.SAITO,S.KOSHIBA,M.INOUE,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURES OF THE C2H2 TYPE ZINC FINGERTITL 2 DOMAIN OF HUMAN ZINC FINGER PROTEIN 462REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants