General Structure Information
| PDB ID | 4ido |
| HGNC Gene Label(s) | ATL1 |
| Structure Name | human atlastin-1 1-446, c-his6, gdpalf4- |
| Resolution | 2.09Å |
| Reference | AUTH L.J.BYRNES,A.SINGH,K.SZETO,N.M.BENVIN,J.P.ODONNELL,AUTH 2 W.R.ZIPFEL,H.SONDERMANNTITL STRUCTURAL BASIS FOR CONFORMATIONAL SWITCHING AND GTPTITL 2 LOADING OF THE LARGE G PROTEIN ATLASTIN.REF EMBO J. V. 32 369 2013REFN ISSN 0261-4189PMID 23334294DOI 10.1038/EMBOJ.2012.353 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 416 |
| Number Of SNVs | 60 |
| Number Of Permutations | 67002 |
| Optimal Distance Threshold | 18.0 |
| K Statistic | 0.193 |
| p-value | 0.833 |
ClinVar
| Number Of Residues | 416 |
| Number Of SNVs | 11 |
| Number Of Permutations | 14641 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.036 |
| p-value | 0.245 |
COSMIC
| Number Of Residues | 416 |
| Number Of SNVs | 8 |
| Number Of Permutations | 3062 |
| Optimal Distance Threshold | 25.0 |
| K Statistic | 0.143 |
| p-value | 0.254 |
Ripley’s K Analysis Plots
ExACClinVarCOSMIC
Variant Set Comparisons
ClinVar vs. ExAC
| Number Of ExAC SNVs | 60 |
| Number Of ClinVar SNVs | 11 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.024 |
| p-value | 0.328 |
Cosmic vs. ExAC
| Number Of ExAC SNVs | 60 |
| Number Of COSMIC SNVs | 8 |
| Optimal Distance Threshold | 44.0 |
| K Statistic | 0.268 |
| p-value | 0.737 |