Assessment of Structural Intolerance and Durability
General Structure Information 3d2s MBNL1 crystal structure of mbnl1 tandem zinc finger 3 and 4 domain in complex with cgcugu rna 1.7Å AUTH M.TEPLOVA,D.J.PATELTITL STRUCTURAL INSIGHTS INTO RNA RECOGNITION BY THETITL 2 ALTERNATIVE-SPLICING REGULATOR MUSCLEBLIND-LIKE MBNL1.REF NAT.STRUCT.MOL.BIOL. V. 15 1343 2008REFN ISSN 1545-9993PMID 19043415DOI 10.1038/NSMB.1519 Variant Set Distributions Mapped Variants
General Structure Information 2d9o DNAJC17 solution structure of rna binding domain in hypothetical protein flj10634 -1.0Å AUTH K.TSUDA,Y.MUTO,M.INOUE,T.KIGAWA,T.TERADA,AUTH 2 M.SHIROUZU,S.YOKOYAMATITL SOLUTION STRUCTURE OF RNA BINDING DOMAIN INTITL 2 HYPOTHETICAL PROTEIN FLJ10634REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1v95 NCOA5 solution structure of anticodon binding domain from nuclear receptor coactivator 5 (human kiaa1637 protein) -1.0Å AUTH C.ZHAO,T.KIGAWA,N.TOCHIO,S.KOSHIBA,M.INOUE,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF ANTICODON BINDING DOMAINTITL 2 FROM NUCLEAR RECEPTOR COACTIVATOR 5 (HUMANTITL 3 KIAA1637 PROTEIN)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 4msp FKBP14 crystal structure of human peptidyl-prolyl cis-trans isomerase fkbp22 (aka fkbp14) containing two ef-hand motifs 1.9Å AUTH S.P.BOUDKO,Y.ISHIKAWA,J.NIX,M.S.CHAPMAN,H.P.BACHINGERTITL STRUCTURE OF HUMAN PEPTIDYL-PROLYL CIS-TRANS ISOMERASETITL 2 FKBP22 CONTAINING TWO EF-HAND MOTIFS.REF PROTEIN SCI. V. 23 67 2014REFN ISSN 0961-8368PMID 24272907DOI 10.1002/PRO.2391 Variant Set Distributions Mapped Variants
General Structure Information 2dmq LHX9 solution structure of the homeobox domain of lim/homeobox protein lhx9 -1.0Å AUTH S.OHNISHI,N.TOCHIO,S.KOSHIBA,M.INOUE,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE HOMEOBOX DOMAIN OFTITL 2 LIM/HOMEOBOX PROTEIN LHX9REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3vow APOBEC3C crystal structure of the human apobec3c having hiv-1 vif-binding interface 2.15Å AUTH S.KITAMURA,H.ODE,M.NAKASHIMA,M.IMAHASHI,Y.NAGANAWA,AUTH 2 T.KUROSAWA,Y.YOKOMAKU,T.YAMANE,N.WATANABE,A.SUZUKI,AUTH 3 W.SUGIURA,Y.IWATANITITL THE APOBEC3C CRYSTAL STRUCTURE AND THE INTERFACE FOR HIV-1TITL 2 VIF BINDING.REF NAT.STRUCT.MOL.BIOL. V. 19 1005 2012REFN ISSN 1545-9993PMID 23001005DOI 10.1038/NSMB.2378 Variant Set Distributions Mapped Variants
General Structure Information 3t6j DPP3 structure of human dppiii in complex with the opioid peptide tynorphin, at 3.0 angstroms 2.98Å AUTH G.A.BEZERRA,E.DOBROVETSKY,R.VIERTLMAYR,A.DONG,A.BINTER,AUTH 2 M.ABRAMIC,P.MACHEROUX,S.DHE-PAGANON,K.GRUBERTITL ENTROPY-DRIVEN BINDING OF OPIOID PEPTIDES INDUCES A LARGETITL 2 DOMAIN MOTION IN HUMAN DIPEPTIDYL PEPTIDASE III.REF PROC.NATL.ACAD.SCI.USA V. 109 6525 2012REFN ISSN 0027-8424PMID 22493238DOI 10.1073/PNAS.1118005109 Variant Set Distributions Ripley’s K Analysis […]
General Structure Information 3lxx GIMAP4 crystal structure of human gtpase imap family member 4 2.15Å AUTH Y.SHEN,L.NEDYALKOVA,Y.TONG,W.TEMPEL,F.MACKENZIE,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,C.BOUNTRA,J.WEIGELT,AUTH 3 A.BOCHKAREV,D.W.ANDREWS,H.PARKTITL CRYSTAL STRUCTURE OF HUMAN GTPASE IMAP FAMILYTITL 2 MEMBER 4REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2io1 SENP2 crystal structure of human senp2 in complex with presumo-3 2.6Å AUTH D.REVERTER,C.D.LIMATITL STRUCTURAL BASIS FOR SENP2 PROTEASE INTERACTIONSTITL 2 WITH SUMO PRECURSORS AND CONJUGATED SUBSTRATES.REF NAT.STRUCT.MOL.BIOL. V. 13 1060 2006REFN ISSN 1545-9993PMID 17099700DOI 10.1038/NSMB1168 Variant Set Distributions Mapped Variants
General Structure Information 2ek1 RBM12 crystal structure of rna-binding motif of human rna-binding protein 12 2.0Å AUTH IHSANAWATI,Y.BESSHO,M.SHIROUZU,S.YOKOYAMATITL CRYSTAL STRUCTURE OF RNA-BINDING MOTIF OF HUMANTITL 2 RNA-BINDING PROTEIN 12REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants