General Structure Information
| PDB ID | 3lxx |
| HGNC Gene Label(s) | GIMAP4 |
| Structure Name | crystal structure of human gtpase imap family member 4 |
| Resolution | 2.15Å |
| Reference | AUTH Y.SHEN,L.NEDYALKOVA,Y.TONG,W.TEMPEL,F.MACKENZIE,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,C.BOUNTRA,J.WEIGELT,AUTH 3 A.BOCHKAREV,D.W.ANDREWS,H.PARKTITL CRYSTAL STRUCTURE OF HUMAN GTPASE IMAP FAMILYTITL 2 MEMBER 4REF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 166 |
| Number Of SNVs | 47 |
| Number Of Permutations | 4271 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | 0.297 |
| p-value | 0.034 |
COSMIC
| Number Of Residues | 166 |
| Number Of SNVs | 5 |
| Number Of Permutations | 1367 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.2 |
| p-value | 0.326 |
Ripley’s K Analysis Plots
ExACCOSMIC


Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 47 |
| Number Of COSMIC SNVs | 5 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.069 |
| p-value | 0.737 |