Assessment of Structural Intolerance and Durability
General Structure Information 2r55 STARD5 human star-related lipid transfer protein 5 2.5Å AUTH A.G.THORSELL,W.H.LEE,C.PERSSON,M.I.SIPONEN,M.NILSSON,AUTH 2 R.D.BUSAM,T.KOTENYOVA,H.SCHULER,L.LEHTIOTITL COMPARATIVE STRUCTURAL ANALYSIS OF LIPID BINDING STARTTITL 2 DOMAINS.REF PLOS ONE V. 6 19521 2011REFN ESSN 1932-6203PMID 21738568DOI 10.1371/JOURNAL.PONE.0019521 Variant Set Distributions Mapped Variants
General Structure Information 4hfg RPRD1B cid of human rprd1b 2.0Å AUTH Z.NI,C.XU,W.TEMPEL,M.EL BAKKOURI,P.LOPPNAU,X.GUO,C.BOUNTRA,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,J.MIN,J.F.GREENBLATTTITL CID OF HUMAN RPRD1BREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3o65 ATXN3L crystal structure of a josephin-ubiquitin complex: evolutionary restraints on ataxin-3 deubiquitinating activity 2.7Å AUTH S.D.WEEKS,K.C.GRASTY,L.HERNANDEZ-CUEBAS,P.J.LOLLTITL CRYSTAL STRUCTURE OF A JOSEPHIN-UBIQUITIN COMPLEX:TITL 2 EVOLUTIONARY RESTRAINTS ON ATAXIN-3 DEUBIQUITINATINGTITL 3 ACTIVITY.REF J.BIOL.CHEM. V. 286 4555 2011REFN ISSN 0021-9258PMID 21118805DOI 10.1074/JBC.M110.177360 Variant Set Distributions Mapped Variants
General Structure Information 3ega PELI2 crystal structure of pellino2 fha domain at 1.8 angstroms resolution 1.8Å AUTH C.C.LIN,Y.S.HUOH,K.R.SCHMITZ,L.E.JENSEN,K.M.FERGUSONTITL PELLINO PROTEINS CONTAIN A CRYPTIC FHA DOMAIN THAT MEDIATESTITL 2 INTERACTION WITH PHOSPHORYLATED IRAK1.REF STRUCTURE V. 16 1806 2008REFN ISSN 0969-2126PMID 19081057DOI 10.1016/J.STR.2008.09.011 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped […]
General Structure Information 1ugk SYT4 solution structure of the first c2 domain of synaptotagmin iv from human fetal brain (kiaa1342) -1.0Å AUTH T.NAGASHIMA,F.HAYASHI,M.SHIROUZU,T.TERADA,T.KIGAWA,AUTH 2 M.INOUE,T.YABUKI,M.AOKI,E.SEKI,T.MATSUDA,H.HIROTA,AUTH 3 M.YOSHIDA,A.TANAKA,T.OSANAI,Y.MATSUO,O.OHARA,AUTH 4 T.NAGASE,R.KIKUNO,M.NAKAYAMA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FIRST C2 DOMAIN OFTITL 2 SYNAPTOTAGMIN IV FROM HUMAN FETAL BRAIN (KIAA1342)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2jqz SMURF2 solution structure of the c2 domain of human smurf2 -1.0Å AUTH S.WIESNER,A.A.OGUNJIMI,H.-R.WANG,D.ROTIN,F.SICHERI,AUTH 2 J.L.WRANA,J.D.FORMAN-KAYTITL AUTOINHIBITION OF THE HECT-TYPE UBIQUITIN LIGASETITL 2 SMURF2 THROUGH ITS C2 DOMAINREF CELL(CAMBRIDGE,MASS.) V. 130 651 2007REFN ISSN 0092-8674PMID 17719543DOI 10.1016/J.CELL.2007.06.050 Variant Set Distributions Mapped Variants
General Structure Information 2dnn RBM12 solution structure of rna binding domain in rna-binding protein 12 -1.0Å AUTH K.TSUDA,Y.MUTO,M.INOUE,T.KIGAWA,T.TERADA,AUTH 2 M.SHIROUZU,S.YOKOYAMATITL SOLUTION STRUCTURE OF RNA BINDING DOMAIN INTITL 2 RNA-BINDING PROTEIN 12REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3kn1 GOLPH3 crystal structure of golgi phosphoprotein 3 n-term truncation variant 2.9Å AUTH C.S.WOOD,K.R.SCHMITZ,N.J.BESSMAN,T.G.SETTY,AUTH 2 K.M.FERGUSON,C.G.BURDTITL PTDINS4P RECOGNITION BY VPS74/GOLPH3 LINKS PTDINSTITL 2 4-KINASE SIGNALING TO RETROGRADE GOLGI TRAFFICKING.REF J.CELL BIOL. V. 187 967 2009REFN ISSN 0021-9525PMID 20026658DOI 10.1083/JCB.200909063 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2xus BRMS1 crystal structure of the brms1 n-terminal region 1.912Å AUTH M.SPINOLA-AMILIBIA,J.RIVERA,M.ORTIZ-LOMBARDIA,A.ROMERO,AUTH 2 J.L.NEIRA,J.BRAVOTITL THE STRUCTURE OF BRMS1 NUCLEAR EXPORT SIGNAL AND SNX6TITL 2 INTERACTING REGION REVEALS A HEXAMER FORMED BY ANTIPARALLELTITL 3 COILED COILS.REF J.MOL.BIOL. V. 411 1114 2011REFN ISSN 0022-2836PMID 21777593DOI 10.1016/J.JMB.2011.07.006 Variant Set Distributions Mapped Variants
General Structure Information 4jqf OBFC1 structure of the c-terminal domain of human telomeric stn1 1.6Å AUTH C.BRYAN,C.RICE,M.HARKISHEIMER,D.C.SCHULTZ,E.SKORDALAKESTITL STRUCTURE OF THE HUMAN TELOMERIC STN1-TEN1 CAPPING COMPLEX.REF PLOS ONE V. 8 66756 2013REFN ESSN 1932-6203PMID 23826127DOI 10.1371/JOURNAL.PONE.0066756 Variant Set Distributions Mapped Variants