Assessment of Structural Intolerance and Durability
General Structure Information 1ft8 NXF1 crystal structure of the rna-binding domain of the mrna export factor tap 3.15Å AUTH E.LIKER,E.FERNANDEZ,E.IZAURRALDE,E.CONTITITL THE STRUCTURE OF THE MRNA EXPORT FACTOR TAPTITL 2 REVEALS A CIS ARRANGEMENT OF A NON-CANONICAL RNPTITL 3 DOMAIN AND AN LRR DOMAIN.REF EMBO J. V. 19 5587 2000REFN ISSN 0261-4189PMID 11060011DOI 10.1093/EMBOJ/19.21.5587 Variant Set […]
General Structure Information 1wiz SATB2 solution structure of the first cut domain of kiaa1034 protein -1.0Å AUTH K.INOUE,S.NAMEKI,F.HAYASHI,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FIRST CUT DOMAIN OFTITL 2 KIAA1034 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2jw5 POLL polymerase lambda brct domain -1.0Å AUTH G.A.MUELLER,A.F.MOON,E.F.DEROSE,B.J.DAVIS,AUTH 2 D.A.RAMSDEN,L.C.PEDERSEN,R.E.LONDONTITL POLYMERASE LAMBDA BRCT DOMAINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 4h9p DAXX complex structure 3 of daxx/h3.3(sub5,g90a)/h4 2.2Å AUTH S.J.ELSASSER,H.HUANG,P.W.LEWIS,J.W.CHIN,D.C.ALLIS,D.J.PATELTITL DAXX CHAPERONE ENVELOPS AN H3.3/H4 DIMER DICTATINGTITL 2 H3.3-SPECIFIC READ OUTREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2c5l PLCE1 structure of plc epsilon ras association domain with hras 1.9Å AUTH T.D.BUNNEY,R.HARRIS,N.L.GANDARILLAS,M.B.JOSEPHS,AUTH 2 S.M.ROE,S.C.SORLI,H.F.PATERSON,F.RODRIGUES-LIMA,AUTH 3 D.ESPOSITO,C.P.PONTING,P.GIESCHIK,L.H.PEARL,AUTH 4 P.C.DRISCOLL,M.KATANTITL STRUCTURAL AND MECHANISTIC INSIGHTS INTO RASTITL 2 ASSOCIATION DOMAINS OF PHOSPHOLIPASE C EPSILONREF MOL.CELL V. 21 495 2006REFN ISSN 1097-2765PMID 16483931DOI 10.1016/J.MOLCEL.2006.01.008 Variant Set Distributions Mapped Variants
General Structure Information 1wi3 SATB2 solution structure of the homeodomain of kiaa1034 protein -1.0Å AUTH K.IZUMI,M.YOSHIDA,F.HAYASHI,R.HATTA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE HOMEODOMAIN OF KIAA1034TITL 2 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3tg5 SMYD2 structure of smyd2 in complex with p53 and sah 2.3Å AUTH L.WANG,L.LI,H.ZHANG,X.LUO,J.DAI,S.ZHOU,J.GU,J.ZHU,P.ATADJA,AUTH 2 C.LU,E.LI,K.ZHAOTITL STRUCTURE OF HUMAN SMYD2 REVEALS THE BASIS OF P53 TUMORTITL 2 SUPPRESSOR METHYLATIONREF J.BIOL.CHEM. 2011REFN ESSN 1083-351XPMID 21880715DOI 10.1074/JBC.M111.262410 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2err RBFOX1 nmr structure of the rna binding domain of human fox-1 in complex with ugcaugu -1.0Å AUTH S.D.AUWETER,R.FASAN,L.REYMOND,J.G.UNDERWOOD,AUTH 2 D.L.BLACK,S.PITSCH,F.H.ALLAINTITL MOLECULAR BASIS OF RNA RECOGNITION BY THE HUMANTITL 2 ALTERNATIVE SPLICING FACTOR FOX-1.REF EMBO J. V. 25 163 2006REFN ISSN 0261-4189PMID 16362037DOI 10.1038/SJ.EMBOJ.7600918 Variant Set Distributions Ripley’s K Analysis Plots Variant […]
General Structure Information 3nhb ABCB6 nucleotide binding domain of human abcb6 (adp bound structure) 2.15Å AUTH M.HAFFKE,A.MENZEL,Y.CARIUS,D.JAHN,D.W.HEINZTITL STRUCTURES OF THE NUCLEOTIDE-BINDING DOMAIN OF THE HUMANTITL 2 ABCB6 TRANSPORTER AND ITS COMPLEXES WITH NUCLEOTIDES.REF ACTA CRYSTALLOGR.,SECT.D V. 66 979 2010REFN ISSN 0907-4449PMID 20823549DOI 10.1107/S0907444910028593 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity […]
General Structure Information 2kt0 NANOG solution structure of human stem cell transcription factor nanog homeodomain fragment -1.0Å AUTH S.C.SAHU,J.L.MARKLEYTITL SOLUTION STRUCTURE OF HUMAN STEM CELL TRANSCRIPTION FACTORTITL 2 NANOGREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants