General Structure Information
| PDB ID | 1ft8 |
| HGNC Gene Label(s) | NXF1 |
| Structure Name | crystal structure of the rna-binding domain of the mrna export factor tap |
| Resolution | 3.15Å |
| Reference | AUTH E.LIKER,E.FERNANDEZ,E.IZAURRALDE,E.CONTITITL THE STRUCTURE OF THE MRNA EXPORT FACTOR TAPTITL 2 REVEALS A CIS ARRANGEMENT OF A NON-CANONICAL RNPTITL 3 DOMAIN AND AN LRR DOMAIN.REF EMBO J. V. 19 5587 2000REFN ISSN 0261-4189PMID 11060011DOI 10.1093/EMBOJ/19.21.5587 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 244 |
| Number Of SNVs | 38 |
| Number Of Permutations | 29002 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.075 |
| p-value | 0.93 |
COSMIC
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 38 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 27.0 |
| K Statistic | 0.475 |
| p-value | 0.619 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
