Assessment of Structural Intolerance and Durability
General Structure Information 2ld4 CIAPIN1 solution structure of the n-terminal domain of human anamorsin -1.0Å AUTH L.BANCI,I.BERTINI,S.CIOFI-BAFFONI,F.BOSCARO,A.CHATZI,AUTH 2 M.MIKOLAJCZYK,K.TOKATLIDIS,J.WINKELMANNTITL ANAMORSIN IS A [2FE-2S] CLUSTER-CONTAINING SUBSTRATE OF THETITL 2 MIA40-DEPENDENT MITOCHONDRIAL PROTEIN TRAPPING MACHINERY.REF CHEM.BIOL. V. 18 794 2011REFN ISSN 1074-5521PMID 21700214DOI 10.1016/J.CHEMBIOL.2011.03.015 Variant Set Distributions Mapped Variants
General Structure Information 3soo L1TD1 crystal structure of a line-1 type transposase domain-containing protein 1 (l1td1) from homo sapiens at 2.73 a resolution 2.73Å AUTH JOINT CENTER FOR STRUCTURAL GENOMICS (JCSG),AUTH 2 PARTNERSHIP FOR STEM CELL BIOLOGY (STEMCELL)TITL CRYSTAL STRUCTURE OF A LINE-1 TYPE TRANSPOSASETITL 2 DOMAIN-CONTAINING PROTEIN 1 (L1TD1) FROM HOMO SAPIENS ATTITL 3 […]
General Structure Information 2nt2 SSH2 crystal structure of slingshot phosphatase 2 2.1Å AUTH S.K.JUNG,D.G.JEONG,T.S.YOON,J.H.KIM,S.E.RYU,S.J.KIMTITL CRYSTAL STRUCTURE OF HUMAN SLINGSHOT PHOSPHATASE 2.REF PROTEINS V. 68 408 2007REFN ISSN 0887-3585PMID 17427953DOI 10.1002/PROT.21399 Variant Set Distributions Mapped Variants
General Structure Information 2qms GRB7 crystal structure of a signaling molecule 2.1Å AUTH C.J.PORTER,J.M.MATTHEWS,J.P.MACKAY,S.E.PURSGLOVE,AUTH 2 J.W.SCHMIDBERGER,P.J.LEEDMAN,S.C.PERO,D.N.KRAG,AUTH 3 M.C.WILCE,J.A.WILCETITL GRB7 SH2 DOMAIN STRUCTURE AND INTERACTIONS WITH ATITL 2 CYCLIC PEPTIDE INHIBITOR OF CANCER CELL MIGRATIONTITL 3 AND PROLIFERATION.REF BMC STRUCT.BIOL. V. 7 58 2007REFN ESSN 1472-6807PMID 17894853DOI 10.1186/1472-6807-7-58 Variant Set Distributions Mapped Variants
General Structure Information 4itj RIPK1 crystal structure of rip1 kinase in complex with necrostatin-4 1.8Å AUTH T.XIE,W.PENG,Y.LIU,C.YAN,J.MAKI,A.DEGTEREV,J.YUAN,Y.SHITITL STRUCTURAL BASIS OF RIP1 INHIBITION BY NECROSTATINS.REF STRUCTURE V. 21 493 2013REFN ISSN 0969-2126PMID 23473668DOI 10.1016/J.STR.2013.01.016 Variant Set Distributions Mapped Variants
General Structure Information 4itj RIPK1 crystal structure of rip1 kinase in complex with necrostatin-4 1.8Å AUTH T.XIE,W.PENG,Y.LIU,C.YAN,J.MAKI,A.DEGTEREV,J.YUAN,Y.SHITITL STRUCTURAL BASIS OF RIP1 INHIBITION BY NECROSTATINS.REF STRUCTURE V. 21 493 2013REFN ISSN 0969-2126PMID 23473668DOI 10.1016/J.STR.2013.01.016 Variant Set Distributions Mapped Variants
General Structure Information 4itj RIPK1 crystal structure of rip1 kinase in complex with necrostatin-4 1.8Å AUTH T.XIE,W.PENG,Y.LIU,C.YAN,J.MAKI,A.DEGTEREV,J.YUAN,Y.SHITITL STRUCTURAL BASIS OF RIP1 INHIBITION BY NECROSTATINS.REF STRUCTURE V. 21 493 2013REFN ISSN 0969-2126PMID 23473668DOI 10.1016/J.STR.2013.01.016 Variant Set Distributions Mapped Variants
General Structure Information 3ezz DUSP4 crystal structure of human mkp-2 2.9Å AUTH D.G.JEONG,S.K.JUNG,T.S.YOON,E.J.WOO,J.H.KIM,AUTH 2 B.C.PARK,S.E.RYU,S.J.KIMTITL CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF HUMANTITL 2 MKP-2 REVEALS A 24-MER ASSEMBLY.REF PROTEINS V. 76 763 2009REFN ISSN 0887-3585PMID 19415758DOI 10.1002/PROT.22423 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 4jmk DUSP8 structure of dusp8 1.9Å AUTH D.G.JEONG,C.H.WEI,B.KU,T.J.JEON,P.N.CHIEN,J.K.KIM,S.Y.PARK,AUTH 2 H.S.HWANG,S.Y.RYU,H.PARK,D.S.KIM,S.J.KIM,S.E.RYUTITL THE FAMILY-WIDE STRUCTURE AND FUNCTION OF HUMANTITL 2 DUAL-SPECIFICITY PROTEIN PHOSPHATASESREF ACTA CRYSTALLOGR.,SECT.D V. 70 421 2014REFN ISSN 0907-4449DOI 10.1107/S1399004713029866 Variant Set Distributions Mapped Variants
General Structure Information 4n0f FCGRT human fcrn complexed with human serum albumin 3.02Å AUTH V.OGANESYAN,M.M.DAMSCHRODER,K.E.COOK,Q.LI,C.GAO,H.WU,AUTH 2 W.F.DALLACQUATITL STRUCTURAL INSIGHTS INTO NEONATAL FC RECEPTOR-BASEDTITL 2 RECYCLING MECHANISMS.REF J.BIOL.CHEM. V. 289 7812 2014REFN ISSN 0021-9258PMID 24469444DOI 10.1074/JBC.M113.537563 Variant Set Distributions Mapped Variants