General Structure Information 3ezz DUSP4 crystal structure of human mkp-2 2.9Å AUTH D.G.JEONG,S.K.JUNG,T.S.YOON,E.J.WOO,J.H.KIM,AUTH 2 B.C.PARK,S.E.RYU,S.J.KIMTITL CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF HUMANTITL 2 MKP-2 REVEALS A 24-MER ASSEMBLY.REF PROTEINS V. 76 763 2009REFN ISSN 0887-3585PMID 19415758DOI 10.1002/PROT.22423 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 4jmk DUSP8 structure of dusp8 1.9Å AUTH D.G.JEONG,C.H.WEI,B.KU,T.J.JEON,P.N.CHIEN,J.K.KIM,S.Y.PARK,AUTH 2 H.S.HWANG,S.Y.RYU,H.PARK,D.S.KIM,S.J.KIM,S.E.RYUTITL THE FAMILY-WIDE STRUCTURE AND FUNCTION OF HUMANTITL 2 DUAL-SPECIFICITY PROTEIN PHOSPHATASESREF ACTA CRYSTALLOGR.,SECT.D V. 70 421 2014REFN ISSN 0907-4449DOI 10.1107/S1399004713029866 Variant Set Distributions Mapped Variants
General Structure Information 4n0f FCGRT human fcrn complexed with human serum albumin 3.02Å AUTH V.OGANESYAN,M.M.DAMSCHRODER,K.E.COOK,Q.LI,C.GAO,H.WU,AUTH 2 W.F.DALLACQUATITL STRUCTURAL INSIGHTS INTO NEONATAL FC RECEPTOR-BASEDTITL 2 RECYCLING MECHANISMS.REF J.BIOL.CHEM. V. 289 7812 2014REFN ISSN 0021-9258PMID 24469444DOI 10.1074/JBC.M113.537563 Variant Set Distributions Mapped Variants
General Structure Information 4ie2 ARG2 crystal structure of human arginase-2 complexed with inhibitor 1h 2.21Å AUTH A.GOLEBIOWSKI,R.PAUL BECKETT,M.VAN ZANDT,M.K.JI,AUTH 2 D.WHITEHOUSE,T.R.RYDER,E.JAGDMANN,M.ANDREOLI,A.MAZUR,AUTH 3 M.PADMANILAYAM,A.COUSIDO-SIAH,A.MITSCHLER,F.X.RUIZ,AUTH 4 A.PODJARNY,H.SCHROETERTITL 2-SUBSTITUTED-2-AMINO-6-BORONOHEXANOIC ACIDS AS ARGINASETITL 2 INHIBITORS.REF BIOORG.MED.CHEM.LETT. V. 23 2027 2013REFN ISSN 0960-894XPMID 23453840DOI 10.1016/J.BMCL.2013.02.024 Variant Set Distributions Mapped Variants
General Structure Information 1zy7 ADARB1 crystal structure of the catalytic domain of an adenosine deaminase that acts on rna (hadar2) bound to inositol hexakisphosphate (ihp) 1.7Å AUTH M.R.MACBETH,H.L.SCHUBERT,A.P.VANDEMARK,A.T.LINGAM,AUTH 2 C.P.HILL,B.L.BASSTITL INOSITOL HEXAKISPHOSPHATE IS BOUND IN THE ADAR2TITL 2 CORE AND REQUIRED FOR RNA EDITING.REF SCIENCE V. 309 1534 2005REFN ISSN 0036-8075PMID 16141067DOI 10.1126/SCIENCE.1113150 Variant Set […]
General Structure Information 3hlk ACOT2 crystal structure of human mitochondrial acyl-coa thioesterase (acot2) 2.1Å AUTH C.R.MANDEL,B.TWEEL,L.TONGTITL CRYSTAL STRUCTURE OF HUMAN MITOCHONDRIAL ACYL-COATITL 2 THIOESTERASE (ACOT2)REF BIOCHEM.BIOPHYS.RES.COMMUN. V. 385 630 2009REFN ISSN 0006-291XPMID 19497300DOI 10.1016/J.BBRC.2009.05.122 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3n2z PRCP the structure of human prolylcarboxypeptidase at 2.80 angstroms resolution 2.79Å AUTH S.M.SOISSON,S.B.PATEL,P.D.ABEYWICKREMA,N.J.BRYNE,R.E.DIEHL,AUTH 2 D.L.HALL,R.E.FORD,J.C.REID,K.W.RICKERT,J.M.SHIPMAN,S.SHARMA,AUTH 3 K.J.LUMBTITL STRUCTURAL DEFINITION AND SUBSTRATE SPECIFICITY OF THE S28TITL 2 PROTEASE FAMILY: THE CRYSTAL STRUCTURE OF HUMANTITL 3 PROLYLCARBOXYPEPTIDASE.REF BMC STRUCT.BIOL. V. 10 16 2010REFN ESSN 1472-6807PMID 20540760DOI 10.1186/1472-6807-10-16 Variant Set Distributions Ripley’s K Analysis […]
General Structure Information 1he3 BLVRB human biliverdin ix beta reductase: nadp/mesobiliverdin iv alpha ternary complex 1.4Å AUTH P.J.B.PEREIRA,S.MACEDO-RIBEIRO,A.PARRAGA,AUTH 2 R.PEREZ-LUQUE,O.CUNNINGHAM,K.DARCY,T.J.MANTLE,AUTH 3 M.COLLTITL STRUCTURE OF HUMAN BILIVERDIN IX BETA REDUCTASE,TITL 2 AN EARLY FETAL BILIRUBIN IX PRODUCING ENZYMEREF NAT.STRUCT.BIOL. V. 8 215 2001REFN ISSN 1072-8368PMID 11224564DOI 10.1038/84948 Variant Set Distributions Mapped Variants
General Structure Information 2oph DPP4 human dipeptidyl peptidase iv in complex with an alpha amino acid inhibitor 2.4Å AUTH J.L.DUFFY,B.A.KIRK,L.WANG,G.J.EIERMANN,H.HE,B.LEITING,AUTH 2 K.A.LYONS,R.A.PATEL,S.B.PATEL,A.PETROV,G.SCAPIN,J.K.WU,AUTH 3 N.A.THORNBERRY,A.E.WEBERTITL 4-AMINOPHENYLALANINE AND 4-AMINOCYCLOHEXYLALANINETITL 2 DERIVATIVES AS POTENT, SELECTIVE, AND ORALLY BIOAVAILABLETITL 3 INHIBITORS OF DIPEPTIDYL PEPTIDASE IV.REF BIOORG.MED.CHEM.LETT. V. 17 2879 2007REFN ISSN 0960-894XPMID 17350841DOI 10.1016/J.BMCL.2007.02.066 Variant Set Distributions Ripley’s K […]
General Structure Information 1yfk PGAM1 crystal structure of human b type phosphoglycerate mutase 2.7Å AUTH Y.WANG,Z.WEI,L.LIU,Z.CHENG,Y.LIN,F.JI,W.GONGTITL CRYSTAL STRUCTURE OF HUMAN B-TYPE PHOSPHOGLYCERATETITL 2 MUTASE BOUND WITH CITRATE.REF BIOCHEM.BIOPHYS.RES.COMMUN. V. 331 1207 2005REFN ISSN 0006-291XPMID 15883004DOI 10.1016/J.BBRC.2005.03.243 Variant Set Distributions Mapped Variants