General Structure Information
| PDB ID | 3hlk |
| HGNC Gene Label(s) | ACOT2 |
| Structure Name | crystal structure of human mitochondrial acyl-coa thioesterase (acot2) |
| Resolution | 2.1Å |
| Reference | AUTH C.R.MANDEL,B.TWEEL,L.TONGTITL CRYSTAL STRUCTURE OF HUMAN MITOCHONDRIAL ACYL-COATITL 2 THIOESTERASE (ACOT2)REF BIOCHEM.BIOPHYS.RES.COMMUN. V. 385 630 2009REFN ISSN 0006-291XPMID 19497300DOI 10.1016/J.BBRC.2009.05.122 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 403 |
| Number Of SNVs | 76 |
| Number Of Permutations | 27940 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.053 |
| p-value | 0.004 |
COSMIC
| Number Of Residues | 403 |
| Number Of SNVs | 5 |
| Number Of Permutations | 2042 |
| Optimal Distance Threshold | 5.0 |
| K Statistic | 0.1 |
| p-value | 0.712 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 76 |
| Number Of COSMIC SNVs | 5 |
| Optimal Distance Threshold | 5.0 |
| K Statistic | 0.089 |
| p-value | 0.491 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
