3BT1.A | PLAU

General Structure Information 3bt1 PLAU structure of urokinase receptor, urokinase and vitronectin complex 2.8Å AUTH Q.HUAI,A.ZHOU,L.LIN,A.P.MAZAR,G.C.PARRY,J.CALLAHAN,D.E.SHAW,AUTH 2 B.FURIE,B.C.FURIE,M.HUANGTITL CRYSTAL STRUCTURES OF TWO HUMAN VITRONECTIN, UROKINASE ANDTITL 2 UROKINASE RECEPTOR COMPLEXESREF NAT.STRUCT.MOL.BIOL. V. 15 422 2008REFN ISSN 1545-9993PMID 18376415DOI 10.1038/NSMB.1404 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants

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1AXI.A | GH1

General Structure Information 1axi GH1 structural plasticity at the hgh:hghbp interface 2.1Å AUTH S.ATWELL,M.ULTSCH,A.M.DE VOS,J.A.WELLSTITL STRUCTURAL PLASTICITY IN A REMODELED PROTEIN-PROTEINTITL 2 INTERFACE.REF SCIENCE V. 278 1125 1997REFN ISSN 0036-8075PMID 9353194DOI 10.1126/SCIENCE.278.5340.1125 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants

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2LY4.B | TP53

General Structure Information 2ly4 TP53 hmgb1-facilitated p53 dna binding occurs via hmg-box/p53 transactivation domain interaction and is regulated by the acidic tail -1.0Å AUTH J.P.ROWELL,K.L.SIMPSON,K.STOTT,M.WATSON,J.O.THOMASTITL HMGB1-FACILITATED P53 DNA BINDING OCCURS VIA HMG-BOX/P53TITL 2 TRANSACTIVATION DOMAIN INTERACTION, REGULATED BY THE ACIDICTITL 3 TAIL.REF STRUCTURE V. 20 2014 2012REFN ISSN 0969-2126PMID 23063560DOI 10.1016/J.STR.2012.09.004 Variant Set Distributions Ripley’s […]

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3AJQ.A | FTH1

General Structure Information 3ajq FTH1 crystal structure of human h ferritin e140q mutant 1.58Å AUTH T.MASUDA,F.GOTO,T.YOSHIHARA,B.MIKAMITITL THE UNIVERSAL MECHANISM FOR IRON TRANSLOCATION TO THETITL 2 FERROXIDASE SITE IN FERRITIN, WHICH IS MEDIATED BY THE WELLTITL 3 CONSERVED TRANSIT SITEREF BIOCHEM.BIOPHYS.RES.COMMUN. V. 400 94 2010REFN ISSN 0006-291XPMID 20705053DOI 10.1016/J.BBRC.2010.08.017 Variant Set Distributions Mapped Variants

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2XWJ.D | C3

General Structure Information 2xwj C3 crystal structure of complement c3b in complex with factor b 4.0Å AUTH F.FORNERIS,D.RICKLIN,J.WU,A.TZEKOU,R.S.WALLACE,J.D.LAMBRIS,AUTH 2 P.GROSTITL STRUCTURES OF C3B IN COMPLEX WITH FACTORS B AND D GIVETITL 2 INSIGHT INTO COMPLEMENT CONVERTASE FORMATION.REF SCIENCE V. 330 1816 2010REFN ISSN 0036-8075PMID 21205667DOI 10.1126/SCIENCE.1195821 Variant Set Distributions Ripley’s K Analysis Plots Variant Set […]

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4KC3.A | IL33

General Structure Information 4kc3 IL33 cytokine/receptor binary complex 3.27Å AUTH X.LIU,M.HAMMEL,Y.HE,J.A.TAINER,U.S.JENG,L.ZHANG,S.WANG,AUTH 2 X.WANGTITL STRUCTURAL INSIGHTS INTO THE INTERACTION OF IL-33 WITH ITSTITL 2 RECEPTORS.REF PROC.NATL.ACAD.SCI.USA V. 110 14918 2013REFN ISSN 0027-8424PMID 23980170DOI 10.1073/PNAS.1308651110 Variant Set Distributions Mapped Variants

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2COE.A | DNTT

General Structure Information 2coe DNTT solution structure of brct domain of terminal deoxynucleotidyltransferase -1.0Å AUTH T.NAGASHIMA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF BRCT DOMAIN OF TERMINALTITL 2 DEOXYNUCLEOTIDYLTRANSFERASEREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants

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3S5L.A | HLA-DRA

General Structure Information 3s5l HLA-DRA crystal structure of cd4 mutant bound to hla-dr1 2.1Å AUTH X.X.WANG,Y.LI,Y.YIN,M.MO,Q.WANG,W.GAO,L.WANG,R.A.MARIUZZATITL AFFINITY MATURATION OF HUMAN CD4 BY YEAST SURFACE DISPLAYTITL 2 AND CRYSTAL STRUCTURE OF A CD4-HLA-DR1 COMPLEX.REF PROC.NATL.ACAD.SCI.USA V. 108 15960 2011REFN ISSN 0027-8424PMID 21900604DOI 10.1073/PNAS.1109438108 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis […]

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3FJI.A | FGF1

General Structure Information 3fji FGF1 crystal structure of k12v/c83i/c117v mutant of human acidic fibroblast growth factor 2.55Å AUTH J.LEE,M.BLABERTITL STRUCTURAL BASIS OF CONSERVED CYSTEINE IN THETITL 2 FIBROBLAST GROWTH FACTOR FAMILY: EVIDENCE FOR ATITL 3 VESTIGIAL HALF-CYSTINE.REF J.MOL.BIOL. V. 393 128 2009REFN ISSN 0022-2836PMID 19683004DOI 10.1016/J.JMB.2009.08.007 Variant Set Distributions Mapped Variants

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4JNL.U | PLAU

General Structure Information 4jnl PLAU crystal structure of upa in complex with its inhibitor 4- bromobenzylamine at ph 7.4 2.0Å AUTH X.ZHANG,L.JIANG,B.ZHAO,C.YUAN,M.HUANGTITL HALOGEN BONDS IN THE DESIGN OF SERINE PROTEASE INHIBITORSREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants

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