General Structure Information
| PDB ID | 1axi |
| HGNC Gene Label(s) | GH1 |
| Structure Name | structural plasticity at the hgh:hghbp interface |
| Resolution | 2.1Å |
| Reference | AUTH S.ATWELL,M.ULTSCH,A.M.DE VOS,J.A.WELLSTITL STRUCTURAL PLASTICITY IN A REMODELED PROTEIN-PROTEINTITL 2 INTERFACE.REF SCIENCE V. 278 1125 1997REFN ISSN 0036-8075PMID 9353194DOI 10.1126/SCIENCE.278.5340.1125 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 175 |
| Number Of SNVs | 53 |
| Number Of Permutations | 8560 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.104 |
| p-value | 0.833 |
ClinVar
| Number Of Residues | 175 |
| Number Of SNVs | 4 |
| Number Of Permutations | 398 |
| Optimal Distance Threshold | 16.0 |
| K Statistic | 0.0 |
| p-value | 0.206 |
COSMIC
Ripley’s K Analysis Plots
ExACClinVarCOSMIC
Variant Set Comparisons
ClinVar vs. ExAC
| Number Of ExAC SNVs | 53 |
| Number Of ClinVar SNVs | 4 |
| Optimal Distance Threshold | 16.0 |
| K Statistic | -0.291 |
| p-value | 0.216 |
Cosmic vs. ExAC
Pathogenic Proximity Analysis
ClinVar PathProx Analysis
COSMIC PathProx Analysis
