Assessment of Structural Intolerance and Durability
General Structure Information 1s18 CANT1 structure and protein design of human apyrase 1.7Å AUTH J.DAI,J.LIU,Y.DENG,T.M.SMITH,M.LUTITL STRUCTURE AND PROTEIN DESIGN OF A HUMAN PLATELETTITL 2 FUNCTION INHIBITOR.REF CELL(CAMBRIDGE,MASS.) V. 116 649 2004REFN ISSN 0092-8674PMID 15006348DOI 10.1016/S0092-8674(04)00172-2 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3puc TTN atomic resolution structure of titin domain m7 0.96Å AUTH F.SAUER,M.WILMANNSTITL STRUCTURE OF TITIN M7REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1g1c TTN i1 domain from titin 2.1Å AUTH O.MAYANS,J.WUERGES,S.CANELA,M.GAUTEL,M.WILMANNSTITL STRUCTURAL EVIDENCE FOR A POSSIBLE ROLE OFTITL 2 REVERSIBLE DISULPHIDE BRIDGE FORMATION IN THETITL 3 ELASTICITY OF THE MUSCLE PROTEIN TITIN.REF STRUCTURE V. 9 331 2001REFN ISSN 0969-2126PMID 11525170DOI 10.1016/S0969-2126(01)00591-3 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 1nr4 CCL17 high resolution crystal structures of thymus and activation- regulated chemokine 1.72Å AUTH O.A.ASOJO,C.BOULEGUE,D.M.HOOVER,W.LU,J.LUBKOWSKITITL STRUCTURES OF THYMUS AND ACTIVATION-REGULATEDTITL 2 CHEMOKINE (TARC).REF ACTA CRYSTALLOGR.,SECT.D V. 59 1165 2003REFN ISSN 0907-4449PMID 12832759DOI 10.1107/S0907444903009454 Variant Set Distributions Mapped Variants
General Structure Information 2aq0 ERCC4 solution structure of the human homodimeric dna repair protein xpf -1.0Å AUTH D.DAS,K.TRIPSIANES,N.G.JASPERS,J.H.HOEIJMAKERS,AUTH 2 R.KAPTEIN,R.BOELENS,G.FOLKERSTITL THE HHH DOMAIN OF THE HUMAN DNA REPAIR PROTEIN XPFTITL 2 FORMS STABLE HOMODIMERSREF PROTEINS V. 70 1551 2008REFN ISSN 0887-3585PMID 17912758DOI 10.1002/PROT.21635 Variant Set Distributions Mapped Variants
General Structure Information 2kg5 ARAP3 nmr solution structure of arap3-sam -1.0Å AUTH M.LEONE,J.CELLITTI,M.PELLECCHIATITL THE SAM DOMAIN OF THE LIPID PHOSPHATASE SHIP2TITL 2 ADOPTS A COMMON MODEL TO INTERACT WITH ARAP3-SAMTITL 3 AND EPHA2-SAM.REF BMC STRUCT.BIOL. V. 9 59 2009REFN ESSN 1472-6807PMID 19765305DOI 10.1186/1472-6807-9-59 Variant Set Distributions Mapped Variants
General Structure Information 2w4r DHX58 crystal structure of the regulatory domain of human lgp2 2.6Å AUTH D.A.PIPPIG,J.C.HELLMUTH,S.CUI,A.KIRCHHOFER,AUTH 2 K.LAMMENS,A.LAMMENS,A.SCHMIDT,S.ROTHENFUSSER,AUTH 3 K.P.HOPFNERTITL THE REGULATORY DOMAIN OF THE RIG-I FAMILY ATPASETITL 2 LGP2 SENSES DOUBLE-STRANDED RNA.REF NUCLEIC ACIDS RES. V. 37 2014 2009REFN ISSN 0305-1048PMID 19208642DOI 10.1093/NAR/GKP059 Variant Set Distributions Mapped Variants
General Structure Information 3dlj CNDP1 crystal structure of human carnosine dipeptidase 1 2.26Å AUTH E.DOBROVETSKY,A.DONG,A.SEITOVA,H.HE,W.TEMPEL,I.KOZIERADZKI,AUTH 2 C.H.ARROWSMITH,J.WEIGELT,C.BOUNTRA,A.M.EDWARDS,A.BOCHKAREV,AUTH 3 D.COSSARTITL CRYSTAL STRUCTURE OF HUMAN CARNOSINE DIPEPTIDASE 1.REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2ean CNKSR2 solution structure of the n-terminal sam-domain of human kiaa0902 protein (connector enhancer of kinase suppressor of ras 2) -1.0Å AUTH A.K.GORONCY,M.YONEYAMA,S.KOSHIBA,M.INOUE,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE N-TERMINAL SAM-DOMAIN OFTITL 2 HUMAN KIAA0902 PROTEIN (CONNECTOR ENHANCER OFTITL 3 KINASE SUPPRESSOR OF RAS 2)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped […]
General Structure Information 1uen NRCAM solution structure of the third fibronectin iii domain of human kiaa0343 protein -1.0Å AUTH K.MIYAMOTO,T.KIGAWA,F.HAYASHI,M.INOUE,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE THIRD FIBRONECTIN IIITITL 2 DOMAIN OF HUMAN KIAA0343 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants