Assessment of Structural Intolerance and Durability
General Structure Information 4h87 SLC4A1AP crystal structure of a fha domain of kanadaptin (slc4a1ap) from homo sapiens at 1.55 a resolution 1.55Å AUTH JOINT CENTER FOR STRUCTURAL GENOMICS (JCSG)TITL CRYSTAL STRUCTURE OF A FHA DOMAIN OF KANADAPTIN (SLC4A1AP)TITL 2 FROM HOMO SAPIENS AT 1.55 A RESOLUTIONREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3fa2 BARD1 crystal structure of the brca1 associated ring domain (bard1) tandem brct domains 2.2Å AUTH D.FOX 3RD,I.LE TRONG,R.E.STENKAMP,R.E.KLEVITTITL CRYSTAL STRUCTURE OF THE BRCA1 ASSOCIATED RING DOMAINTITL 2 (BARD1) TANDEM BRCT DOMAINSREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 4i1o RAB1B crystal structure of the legionella pneumophila gap domain of lepb in complex with rab1b bound to gdp and bef3 2.7Å AUTH E.MIHAI GAZDAG,A.STRELLER,I.HANEBURGER,H.HILBI,I.R.VETTER,AUTH 2 R.S.GOODY,A.ITZENTITL MECHANISM OF RAB1B DEACTIVATION BY THE LEGIONELLATITL 2 PNEUMOPHILA GAP LEPB.REF EMBO REP. V. 14 199 2013REFN ISSN 1469-221XPMID 23288104DOI 10.1038/EMBOR.2012.211 Variant Set Distributions Ripley’s […]
General Structure Information 2p39 FGF23 crystal structure of human fgf23 1.5Å AUTH R.GOETZ,A.BEENKEN,O.A.IBRAHIMI,J.KALININA,AUTH 2 S.K.OLSEN,A.V.ELISEENKOVA,C.XU,T.A.NEUBERT,F.ZHANG,AUTH 3 R.J.LINHARDT,X.YU,K.E.WHITE,T.INAGAKI,S.A.KLIEWER,AUTH 4 M.YAMAMOTO,H.KUROSU,Y.OGAWA,M.KURO-O,B.LANSKE,AUTH 5 M.S.RAZZAQUE,M.MOHAMMADITITL MOLECULAR INSIGHTS INTO THE KLOTHO-DEPENDENT,TITL 2 ENDOCRINE MODE OF ACTION OF FIBROBLAST GROWTHTITL 3 FACTOR 19 SUBFAMILY MEMBERS.REF MOL.CELL.BIOL. V. 27 3417 2007REFN ISSN 0270-7306PMID 17339340DOI 10.1128/MCB.02249-06 Variant Set Distributions Ripley’s K Analysis Plots […]
General Structure Information 2dgt RBM4B solution structure of the second rna binding domain in rna- binding protein 30 -1.0Å AUTH C.ABE,Y.MUTO,M.INOUE,T.KIGAWA,T.TERADA,M.SHIROUZU,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE SECOND RNA BINDINGTITL 2 DOMAIN IN RNA-BINDING PROTEIN 30REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 4hpl PCGF1 pcgf1 ub fold (rawul)/bcor pufd complex 2.0Å AUTH S.E.JUNCO,R.WANG,J.C.GAIPA,A.B.TAYLOR,V.SCHIRF,M.D.GEARHART,AUTH 2 V.J.BARDWELL,B.DEMELER,P.J.HART,C.A.KIMTITL STRUCTURE OF THE POLYCOMB GROUP PROTEIN PCGF1 IN COMPLEXTITL 2 WITH BCOR REVEALS BASIS FOR BINDING SELECTIVITY OF PCGFTITL 3 HOMOLOGS.REF STRUCTURE V. 21 665 2013REFN ISSN 0969-2126PMID 23523425DOI 10.1016/J.STR.2013.02.013 Variant Set Distributions Mapped Variants
General Structure Information 1ll8 PASK structure and interactions of pas kinase n-terminal pas domain: model for intramolecular kinase regulation -1.0Å AUTH C.A.AMEZCUA,S.M.HARPER,J.RUTTER,K.H.GARDNERTITL STRUCTURE AND INTERACTIONS OF PAS KINASETITL 2 N-TERMINAL PAS DOMAIN: MODEL FOR INTRAMOLECULARTITL 3 KINASE REGULATION.REF STRUCTURE V. 10 1349 2002REFN ISSN 0969-2126PMID 12377121DOI 10.1016/S0969-2126(02)00857-2 Variant Set Distributions Mapped Variants
General Structure Information 4ie5 FTO crystal structure of the human fat mass and obesity associated protein (fto) in complex with n-[(3-hydroxypyridin-2-yl)carbonyl]glycine (md6) 1.95Å AUTH W.S.AIK,M.DEMETRIADES,M.K.K.HAMDAN,E.A.L.BAGG,K.K.YEOH,AUTH 2 C.LEJEUNE,Z.ZHANG,M.A.MCDONOUGH,C.J.SCHOFIELDTITL STRUCTURAL BASIS FOR INHIBITION OF THE FAT MASS AND OBESITYTITL 2 ASSOCIATED PROTEIN (FTO)REF J.MED.CHEM. V. 56 3680 2013REFN ISSN 0022-2623PMID 23547775DOI 10.1021/JM400193D Variant Set Distributions Mapped Variants
General Structure Information 2ypr FEV crystal structure of the dna binding ets domain of human protein fev 2.64Å AUTH C.D.O.COOPER,J.A.NEWMAN,H.AITKENHEAD,C.K.ALLERSTON,AUTH 2 O.GILEADITITL STRUCTURES OF THE ETS DOMAINS OF TRANSCRIPTION FACTORS ETV1,TITL 2 ETV4, ETV5 AND FEV: DETERMINANTS OF DNA BINDING AND REDOXTITL 3 REGULATION BY DISULFIDE BOND FORMATION.REF J.BIOL.CHEM. V. 290 13692 2015REFN ISSN 0021-9258PMID […]
General Structure Information 2daq WHSC1L1 solution structure of second pwwp domain of whsc1l1 protein -1.0Å AUTH T.N.NIRAULA,N.TOCHIO,S.KOSHIBA,M.INOUE,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF SECOND PWWP DOMAIN OFTITL 2 WHSC1L1 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants