Assessment of Structural Intolerance and Durability
General Structure Information 1k93 CALM3 crystal structure of the adenylyl cyclase domain of anthrax edema factor (ef) in complex with calmodulin 2.95Å AUTH C.L.DRUM,S.-Z.YAN,J.BARD,Y.-Q.SHEN,D.LU,AUTH 2 S.SOELAIMAN,Z.GRABAREK,A.BOHM,W.-J.TANGTITL STRUCTURAL BASIS FOR THE ACTIVATION OF ANTHRAXTITL 2 ADENYLYL CYCLASE EXOTOXIN BY CALMODULIN.REF NATURE V. 415 396 2002REFN ISSN 0028-0836PMID 11807546DOI 10.1038/415396A Variant Set Distributions Ripley’s K Analysis Plots […]
General Structure Information 1k93 CALM2 crystal structure of the adenylyl cyclase domain of anthrax edema factor (ef) in complex with calmodulin 2.95Å AUTH C.L.DRUM,S.-Z.YAN,J.BARD,Y.-Q.SHEN,D.LU,AUTH 2 S.SOELAIMAN,Z.GRABAREK,A.BOHM,W.-J.TANGTITL STRUCTURAL BASIS FOR THE ACTIVATION OF ANTHRAXTITL 2 ADENYLYL CYCLASE EXOTOXIN BY CALMODULIN.REF NATURE V. 415 396 2002REFN ISSN 0028-0836PMID 11807546DOI 10.1038/415396A Variant Set Distributions Ripley’s K Analysis Plots […]
General Structure Information 1k93 CALM1 crystal structure of the adenylyl cyclase domain of anthrax edema factor (ef) in complex with calmodulin 2.95Å AUTH C.L.DRUM,S.-Z.YAN,J.BARD,Y.-Q.SHEN,D.LU,AUTH 2 S.SOELAIMAN,Z.GRABAREK,A.BOHM,W.-J.TANGTITL STRUCTURAL BASIS FOR THE ACTIVATION OF ANTHRAXTITL 2 ADENYLYL CYCLASE EXOTOXIN BY CALMODULIN.REF NATURE V. 415 396 2002REFN ISSN 0028-0836PMID 11807546DOI 10.1038/415396A Variant Set Distributions Ripley’s K Analysis Plots […]
General Structure Information 2npl CXADR nmr structure of card d2 domain -1.0Å AUTH S.JIANG,M.CAFFREYTITL SOLUTION STRUCTURE OF THE COXSACKIEVIRUS ANDTITL 2 ADENOVIRUS RECEPTOR DOMAIN 2REF PROTEIN SCI. V. 16 539 2007REFN ISSN 0961-8368PMID 17322536DOI 10.1110/PS.062643507 Variant Set Distributions Mapped Variants
General Structure Information 1a3q NFKB2 human nf-kappa-b p52 bound to dna 2.1Å AUTH P.CRAMER,C.J.LARSON,G.L.VERDINE,C.W.MULLERTITL STRUCTURE OF THE HUMAN NF-KAPPAB P52 HOMODIMER-DNATITL 2 COMPLEX AT 2.1 A RESOLUTION.REF EMBO J. V. 16 7078 1997REFN ISSN 0261-4189PMID 9384586DOI 10.1093/EMBOJ/16.23.7078 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 4my2 NDP crystal structure of norrin in fusion with maltose binding protein 2.4Å AUTH J.KE,K.G.HARIKUMAR,C.ERICE,C.CHEN,X.GU,L.WANG,N.PARKER,AUTH 2 Z.CHENG,W.XU,B.O.WILLIAMS,K.MELCHER,L.J.MILLER,H.E.XUTITL STRUCTURE AND FUNCTION OF NORRIN IN ASSEMBLY AND ACTIVATIONTITL 2 OF A FRIZZLED 4-LRP5/6 COMPLEX.REF GENES DEV. V. 27 2305 2013REFN ISSN 0890-9369PMID 24186977DOI 10.1101/GAD.228544.113 Variant Set Distributions Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3mtl CDK16 crystal structure of the pctaire1 kinase in complex with indirubin e804 2.4Å AUTH T.KROJER,T.D.SHARPE,A.ROOS,P.SAVITSKY,A.AMOS,V.AYINAMPUDI,AUTH 2 G.BERRIDGE,O.FEDOROV,T.KEATES,C.PHILLIPS,N.BURGESS-BROWN,AUTH 3 Y.ZHANG,A.C.W.PIKE,J.MUNIZ,M.VOLLMAR,C.THANGARATNARAJAH,AUTH 4 P.RELLOS,E.UGOCHUKWU,P.FILIPPAKOPOULOS,W.YUE,S.DAS,AUTH 5 F.VON DELFT,A.EDWARDS,C.H.ARROWSMITH,J.WEIGELT,C.BOUNTRA,AUTH 6 S.KNAPP,A.BULLOCKTITL CRYSTAL STRUCTURE OF THE PCTAIRE1 KINASE IN COMPLEX WITHTITL 2 INDIRUBIN E804REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1vyh PAFAH1B2 paf-ah holoenzyme: lis1/alfa2 3.4Å AUTH C.TARRICONE,F.PERRINA,S.MONZANI,L.MASSIMILIANO,AUTH 2 M.H.KIM,Z.S.DEREWENDA,S.KNAPP,L.-H.TSAI,A.MUSACCHIOTITL COUPLING PAF SIGNALING TO DYNEIN REGULATION:TITL 2 STRUCTURE OF LIS1 IN COMPLEX WITH PAF-TITL 3 ACETYLHYDROLASE.REF NEURON V. 44 809 2004REFN ISSN 0896-6273PMID 15572112DOI 10.1016/J.NEURON.2004.11.019 Variant Set Distributions Mapped Variants
General Structure Information 2l6a NLRP12 three-dimensional structure of the n-terminal effector pyrin domain of nlrp12 -1.0Å AUTH A.S.PINHEIRO,C.EIBL,Z.EKMAN-VURAL,R.SCHWARZENBACHER,W.PETITITL THE NLRP12 PYRIN DOMAIN: STRUCTURE, DYNAMICS, AND FUNCTIONALTITL 2 INSIGHTS.REF J.MOL.BIOL. V. 413 790 2011REFN ISSN 0022-2836PMID 21978668DOI 10.1016/J.JMB.2011.09.024 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2ctj HDLBP solution structure of the 8th kh type i domain from human vigilin -1.0Å AUTH T.TOMIZAWA,T.KIGAWA,S.KOSHIBA,M.INOUE,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE 8TH KH TYPE I DOMAINTITL 2 FROM HUMAN VIGILINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants