Assessment of Structural Intolerance and Durability
General Structure Information 2djv MARS solution structures of the whep-trs domain of human methionyl-trna synthetase -1.0Å AUTH M.SATO,A.SASAGAWA,N.TOCHIO,S.KOSHIBA,M.INOUE,AUTH 2 T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURES OF THE WHEP-TRS DOMAIN OFTITL 2 HUMAN METHIONYL-TRNA SYNTHETASEREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 4hre S100A10 crystal structure of p11/annexin a2 heterotetramer in complex with smarca3 peptide 2.79Å AUTH Y.S.OH,P.GAO,K.W.LEE,I.CEGLIA,J.S.SEO,X.ZHANG,J.H.AHN,AUTH 2 B.T.CHAIT,D.J.PATEL,Y.KIM,P.GREENGARDTITL SMARCA3, A CHROMATIN-REMODELING FACTOR, IS REQUIRED FORTITL 2 P11-DEPENDENT ANTIDEPRESSANT ACTION.REF CELL(CAMBRIDGE,MASS.) V. 152 831 2013REFN ISSN 0092-8674PMID 23415230DOI 10.1016/J.CELL.2013.01.014 Variant Set Distributions Mapped Variants
General Structure Information 1uw5 PITPNA structure of pitp-alpha complexed to phosphatidylinositol 2.9Å AUTH S.J.TILLEY,A.SKIPPEN,J.MURRAY-RUST,P.M.SWIGART,AUTH 2 A.STEWART,C.P.MORGAN,S.COCKCROFT,N.Q.MCDONALDTITL STRUCTURE-FUNCTION ANALYSIS OF HUMAN [CORRECTED]TITL 2 PHOSPHATIDYLINOSITOL TRANSFER PROTEIN ALPHA BOUNDTITL 3 TO PHOSPHATIDYLINOSITOL.REF STRUCTURE V. 12 317 2004REFN ISSN 0969-2126PMID 14962392DOI 10.1016/J.STR.2004.01.013 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2ev8 MPP1 solution structure of the erythroid p55 pdz domain -1.0Å AUTH H.KUSUNOKI,T.KOHNOTITL SOLUTION STRUCTURE OF HUMAN ERYTHROID P55 PDZTITL 2 DOMAINREF PROTEINS V. 64 804 2006REFN ISSN 0887-3585PMID 16741958DOI 10.1002/PROT.21028 Variant Set Distributions Mapped Variants
General Structure Information 4hb4 RAN crystal structure of crm1 inhibitor leptomycin b in complex with crm1(537dltvk541/glceq)-ran-ranbp1 2.05Å AUTH Q.SUN,Y.P.CARRASCO,Y.HU,X.GUO,H.MIRZAEI,J.MACMILLAN,AUTH 2 Y.M.CHOOKTITL NUCLEAR EXPORT INHIBITION THROUGH COVALENT CONJUGATION ANDTITL 2 HYDROLYSIS OF LEPTOMYCIN B BY CRM1.REF PROC.NATL.ACAD.SCI.USA V. 110 1303 2013REFN ISSN 0027-8424PMID 23297231DOI 10.1073/PNAS.1217203110 Variant Set Distributions Mapped Variants
General Structure Information 2of5 CRADD oligomeric death domain complex 3.2Å AUTH H.H.PARK,E.LOGETTE,S.RAUNSER,S.CUENIN,T.WALZ,J.TSCHOPP,H.WUTITL DEATH DOMAIN ASSEMBLY MECHANISM REVEALED BY CRYSTALTITL 2 STRUCTURE OF THE OLIGOMERIC PIDDOSOME CORE COMPLEX.REF CELL(CAMBRIDGE,MASS.) V. 128 533 2007REFN ISSN 0092-8674PMID 17289572DOI 10.1016/J.CELL.2007.01.019 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2cr4 SH3BP2 solution structure of the sh2 domain of human sh3bp2 protein -1.0Å AUTH R.HATTA,T.TOMIZAWA,F.HAYASHI,M.YOSHIDA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE SH2 DOMAIN OF HUMANTITL 2 SH3BP2 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3tso RAB25 structure of the cancer associated rab25 protein in complex with fip2 1.8Å AUTH S.ODA,P.Y.LALL,M.W.MCCAFFREY,A.R.KHANTITL STRUCTURE OF THE CANCER ASSOCIATED RAB25 PROTEIN IN COMPLEXTITL 2 WITH FIP2REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3bg0 SEC13 architecture of a coat for the nuclear pore membrane 3.15Å AUTH K.C.HSIA,P.STAVROPOULOS,G.BLOBEL,A.HOELZTITL ARCHITECTURE OF A COAT FOR THE NUCLEAR PORETITL 2 MEMBRANE.REF CELL(CAMBRIDGE,MASS.) V. 131 1313 2007REFN ISSN 0092-8674PMID 18160040DOI 10.1016/J.CELL.2007.11.038 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 1wyx BCAR1 the crystal structure of the p130cas sh3 domain at 1.1 a resolution 1.14Å AUTH M.WISNIEWSKA,B.BOSSENMAIER,G.GEORGES,F.HESSE,AUTH 2 M.DANGL,K.P.KUNKELE,I.IOANNIDIS,R.HUBER,R.A.ENGHTITL THE 1.1 A RESOLUTION CRYSTAL STRUCTURE OF THETITL 2 P130CAS SH3 DOMAIN AND RAMIFICATIONS FOR LIGANDTITL 3 SELECTIVITYREF J.MOL.BIOL. V. 347 1005 2005REFN ISSN 0022-2836PMID 15784259DOI 10.1016/J.JMB.2005.02.017 Variant Set Distributions Mapped Variants