General Structure Information
| PDB ID | 3tso |
| HGNC Gene Label(s) | RAB25 |
| Structure Name | structure of the cancer associated rab25 protein in complex with fip2 |
| Resolution | 1.8Å |
| Reference | AUTH S.ODA,P.Y.LALL,M.W.MCCAFFREY,A.R.KHANTITL STRUCTURE OF THE CANCER ASSOCIATED RAB25 PROTEIN IN COMPLEXTITL 2 WITH FIP2REF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 167 |
| Number Of SNVs | 54 |
| Number Of Permutations | 13483 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.031 |
| p-value | 0.796 |
COSMIC
| Number Of Residues | 167 |
| Number Of SNVs | 3 |
| Number Of Permutations | 67 |
| Optimal Distance Threshold | 24.0 |
| K Statistic | 0.333 |
| p-value | 0.574 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 54 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 18.0 |
| K Statistic | -0.467 |
| p-value | 0.274 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
