Assessment of Structural Intolerance and Durability
General Structure Information 1fli FLI1 dna-binding domain of fli-1 -1.0Å AUTH H.LIANG,X.MAO,E.T.OLEJNICZAK,D.G.NETTESHEIM,L.YU,AUTH 2 R.P.MEADOWS,C.B.THOMPSON,S.W.FESIKTITL SOLUTION STRUCTURE OF THE ETS DOMAIN OF FLI-1 WHENTITL 2 BOUND TO DNA.REF NAT.STRUCT.BIOL. V. 1 871 1994REFN ISSN 1072-8368PMID 7773776DOI 10.1038/NSB1294-871 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 1grn ARHGAP1 crystal structure of the cdc42/cdc42gap/alf3 complex. 2.1Å AUTH N.NASSAR,G.R.HOFFMAN,D.MANOR,J.C.CLARDY,R.A.CERIONETITL STRUCTURES OF CDC42 BOUND TO THE ACTIVE ANDTITL 2 CATALYTICALLY COMPROMISED FORMS OF CDC42GAP.REF NAT.STRUCT.BIOL. V. 5 1047 1998REFN ISSN 1072-8368PMID 9846874DOI 10.1038/4156 Variant Set Distributions Mapped Variants
General Structure Information 1grn ARHGAP1 crystal structure of the cdc42/cdc42gap/alf3 complex. 2.1Å AUTH N.NASSAR,G.R.HOFFMAN,D.MANOR,J.C.CLARDY,R.A.CERIONETITL STRUCTURES OF CDC42 BOUND TO THE ACTIVE ANDTITL 2 CATALYTICALLY COMPROMISED FORMS OF CDC42GAP.REF NAT.STRUCT.BIOL. V. 5 1047 1998REFN ISSN 1072-8368PMID 9846874DOI 10.1038/4156 Variant Set Distributions Mapped Variants
General Structure Information 1grn ARHGAP1 crystal structure of the cdc42/cdc42gap/alf3 complex. 2.1Å AUTH N.NASSAR,G.R.HOFFMAN,D.MANOR,J.C.CLARDY,R.A.CERIONETITL STRUCTURES OF CDC42 BOUND TO THE ACTIVE ANDTITL 2 CATALYTICALLY COMPROMISED FORMS OF CDC42GAP.REF NAT.STRUCT.BIOL. V. 5 1047 1998REFN ISSN 1072-8368PMID 9846874DOI 10.1038/4156 Variant Set Distributions Mapped Variants
General Structure Information 1k05 PTK2 crystal structure of the focal adhesion targeting domain of focal adhesion kinase 2.9Å AUTH S.T.AROLD,M.K.HOELLERER,M.E.NOBLETITL THE STRUCTURAL BASIS OF LOCALIZATION AND SIGNALINGTITL 2 BY THE FOCAL ADHESION TARGETING DOMAIN.REF STRUCTURE V. 10 319 2002REFN ISSN 0969-2126PMID 12005431DOI 10.1016/S0969-2126(02)00717-7 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity […]
General Structure Information 3w9y DLG1 crystal structure of the human dlg1 guanylate kinase domain 2.2Å AUTH S.MORI,Y.TEZUKA,A.ARAKAWA,N.HANDA,M.SHIROUZU,T.AKIYAMA,AUTH 2 S.YOKOYAMATITL CRYSTAL STRUCTURE OF THE GUANYLATE KINASE DOMAIN FROM DISCSTITL 2 LARGE HOMOLOG 1 (DLG1/SAP97)REF BIOCHEM.BIOPHYS.RES.COMMUN. V. 435 334 2013REFN ISSN 0006-291XPMID 23624197DOI 10.1016/J.BBRC.2013.04.056 Variant Set Distributions Mapped Variants
General Structure Information 4ic8 MAPK7 crystal structure of the apo erk5 kinase domain 2.8Å AUTH G.GLATZ,G.GOGL,A.ALEXA,A.REMENYITITL STRUCTURAL MECHANISM FOR THE SPECIFIC ASSEMBLY ANDTITL 2 ACTIVATION OF THE EXTRACELLULAR SIGNAL REGULATED KINASE 5TITL 3 (ERK5) MODULE.REF J.BIOL.CHEM. V. 288 8596 2013REFN ISSN 0021-9258PMID 23382384DOI 10.1074/JBC.M113.452235 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped […]
General Structure Information 4d8o ANK2 crystal structure of the ankyrin-b zu5-zu5-upa-dd tandem 2.2Å AUTH C.WANG,C.YU,F.YE,Z.WEI,M.ZHANGTITL STRUCTURE OF THE ZU5-ZU5-UPA-DD TANDEM OF ANKYRIN-B REVEALSTITL 2 INTERACTION SURFACES NECESSARY FOR ANKYRIN FUNCTIONREF PROC.NATL.ACAD.SCI.USA V. 109 4822 2012REFN ISSN 0027-8424PMID 22411828DOI 10.1073/PNAS.1200613109 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 1ism BST1 crystal structure analysis of bst-1/cd157 complexed with nicotinamide 3.0Å AUTH S.YAMAMOTO-KATAYAMA,M.ARIYOSHI,K.ISHIHARA,T.HIRANO,AUTH 2 H.JINGAMI,K.MORIKAWATITL CRYSTALLOGRAPHIC STUDIES ON HUMAN BST-1/CD157 WITHTITL 2 ADP-RIBOSYL CYCLASE AND NAD GLYCOHYDROLASE ACTIVITIES.REF J.MOL.BIOL. V. 316 711 2002REFN ISSN 0022-2836PMID 11866528DOI 10.1006/JMBI.2001.5386 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 1e7z AIMP1 crystal structure of the emap2/rna binding domain of the p43 protein from human aminoacyl-trna synthetase complex 2.05Å AUTH L.RENAULT,P.KERJAN,S.PASQUALATO,J.MENETREY,AUTH 2 J.C.ROBINSON,S.KAWAGUCHI,D.G.VASSYLYEV,S.YOKOYAMA,AUTH 3 M.MIRANDE,J.CHERFILSTITL STRUCTURE OF THE EMAPII DOMAIN OF HUMAN AMINOACYL-TITL 2 TRNA SYNTHETASE COMPLEX REVEALS EVOLUTIONARYTITL 3 DIMERIC MIMICRYREF EMBO J. V. 20 570 2001REFN ISSN 0261-4189PMID 11157763DOI 10.1093/EMBOJ/20.3.570 […]