Assessment of Structural Intolerance and Durability
General Structure Information 1p5q FKBP4 crystal structure of fkbp52 c-terminal domain 2.8Å AUTH B.WU,P.LI,Y.LIU,Z.LOU,Y.DING,C.SHU,S.YE,M.BARTLAM,B.SHEN,AUTH 2 Z.RAOTITL 3D STRUCTURE OF HUMAN FK506-BINDING PROTEIN 52: IMPLICATIONSTITL 2 FOR THE ASSEMBLY OF THE GLUCOCORTICOIDTITL 3 RECEPTOR/HSP90/IMMUNOPHILIN HETEROCOMPLEXREF PROC.NATL.ACAD.SCI.USA V. 101 8348 2004REFN ISSN 0027-8424PMID 15159550DOI 10.1073/PNAS.0305969101 Variant Set Distributions Mapped Variants
General Structure Information 2lmi GRSF1 nmr structure of the protein bc040485 from homo sapiens -1.0Å AUTH S.K.DUTTA,P.SERRANO,M.GERALT,K.WUTHRICH,AUTH 2 JOINT CENTER FOR STRUCTURAL GENOMICS (JCSG),AUTH 3 PARTNERSHIP FOR T-CELL BIOLOGY (TCELL)TITL NMR STRUCTURE OF THE HUMAN RNA BINDING PROTEIN BC040485REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2lmi GRSF1 nmr structure of the protein bc040485 from homo sapiens -1.0Å AUTH S.K.DUTTA,P.SERRANO,M.GERALT,K.WUTHRICH,AUTH 2 JOINT CENTER FOR STRUCTURAL GENOMICS (JCSG),AUTH 3 PARTNERSHIP FOR T-CELL BIOLOGY (TCELL)TITL NMR STRUCTURE OF THE HUMAN RNA BINDING PROTEIN BC040485REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2lmi GRSF1 nmr structure of the protein bc040485 from homo sapiens -1.0Å AUTH S.K.DUTTA,P.SERRANO,M.GERALT,K.WUTHRICH,AUTH 2 JOINT CENTER FOR STRUCTURAL GENOMICS (JCSG),AUTH 3 PARTNERSHIP FOR T-CELL BIOLOGY (TCELL)TITL NMR STRUCTURE OF THE HUMAN RNA BINDING PROTEIN BC040485REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3pls MST1R ron in complex with ligand amp-pnp 2.24Å AUTH J.WANG,S.STEINBACHER,M.AUGUSTIN,P.SCHREINER,D.EPSTEIN,AUTH 2 M.J.MULVIHILL,A.P.CREWTITL THE CRYSTAL STRUCTURE OF A CONSTITUTIVELY ACTIVE MUTANT RONTITL 2 KINASE SUGGESTS AN INTRAMOLECULAR AUTOPHOSPHORYLATIONTITL 3 HYPOTHESISREF BIOCHEMISTRY V. 49 7972 2010REFN ISSN 0006-2960PMID 20726546 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3pls MST1R ron in complex with ligand amp-pnp 2.24Å AUTH J.WANG,S.STEINBACHER,M.AUGUSTIN,P.SCHREINER,D.EPSTEIN,AUTH 2 M.J.MULVIHILL,A.P.CREWTITL THE CRYSTAL STRUCTURE OF A CONSTITUTIVELY ACTIVE MUTANT RONTITL 2 KINASE SUGGESTS AN INTRAMOLECULAR AUTOPHOSPHORYLATIONTITL 3 HYPOTHESISREF BIOCHEMISTRY V. 49 7972 2010REFN ISSN 0006-2960PMID 20726546 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3pls MST1R ron in complex with ligand amp-pnp 2.24Å AUTH J.WANG,S.STEINBACHER,M.AUGUSTIN,P.SCHREINER,D.EPSTEIN,AUTH 2 M.J.MULVIHILL,A.P.CREWTITL THE CRYSTAL STRUCTURE OF A CONSTITUTIVELY ACTIVE MUTANT RONTITL 2 KINASE SUGGESTS AN INTRAMOLECULAR AUTOPHOSPHORYLATIONTITL 3 HYPOTHESISREF BIOCHEMISTRY V. 49 7972 2010REFN ISSN 0006-2960PMID 20726546 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3rcq ASPH crystal structure of human aspartate beta-hydroxylase isoform a 2.05Å AUTH T.KROJER,G.KOCHAN,E.PILKA,V.HOZJAN,C.K.ALLERSTON,J.BRAY,AUTH 2 J.R.MUNIZ,A.CHAIKUAD,O.GILEADI,K.KAVANAGH,F.VON DELFT,AUTH 3 C.BOUNTRA,C.H.ARROWSMITH,J.WEIGELT,A.EDWARDS,U.OPPERMANNTITL CRYSTAL STRUCTURE OF HUMAN ASPARTATE BETA-HYDROXYLASETITL 2 ISOFORM AREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2lg1 AKAP13 solution structure of the human akap13 ph domain and stabilizing dh helix -1.0Å AUTH M.LENOIR,M.SUGAWARA,J.KAUR,L.J.BALL,M.OVERDUINTITL STRUCTURAL INSIGHTS INTO THE ACTIVATION OF THE RHOA GTPASETITL 2 BY THE LBC ONCOPROTEIN.REF J.BIOL.CHEM. V. 3 215 2014REFN ISSN 0021-9258PMID 24993829DOI 10.1074/JBC.M114.561787 Variant Set Distributions Mapped Variants
General Structure Information 1nrv GRB10 crystal structure of the sh2 domain of grb10 1.65Å AUTH E.G.STEIN,R.GHIRLANDO,S.R.HUBBARDTITL STRUCTURAL BASIS FOR DIMERIZATION OF THE GRB10 SRCTITL 2 HOMOLOGY 2 DOMAIN. IMPLICATIONS FOR LIGANDTITL 3 SPECIFICITY.REF J.BIOL.CHEM. V. 278 13257 2003REFN ISSN 0021-9258PMID 12551896DOI 10.1074/JBC.M212026200 Variant Set Distributions Mapped Variants