General Structure Information
| PDB ID | 3pls |
| HGNC Gene Label(s) | MST1R |
| Structure Name | ron in complex with ligand amp-pnp |
| Resolution | 2.24Å |
| Reference | AUTH J.WANG,S.STEINBACHER,M.AUGUSTIN,P.SCHREINER,D.EPSTEIN,AUTH 2 M.J.MULVIHILL,A.P.CREWTITL THE CRYSTAL STRUCTURE OF A CONSTITUTIVELY ACTIVE MUTANT RONTITL 2 KINASE SUGGESTS AN INTRAMOLECULAR AUTOPHOSPHORYLATIONTITL 3 HYPOTHESISREF BIOCHEMISTRY V. 49 7972 2010REFN ISSN 0006-2960PMID 20726546 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 298 |
| Number Of SNVs | 89 |
| Number Of Permutations | 16014 |
| Optimal Distance Threshold | 16.0 |
| K Statistic | 0.177 |
| p-value | 0.329 |
COSMIC
| Number Of Residues | 298 |
| Number Of SNVs | 4 |
| Number Of Permutations | 193 |
| Optimal Distance Threshold | 24.0 |
| K Statistic | 0.167 |
| p-value | 0.427 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 89 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 29.0 |
| K Statistic | -0.633 |
| p-value | 0.086 |