General Structure Information
| PDB ID | 1k05 |
| HGNC Gene Label(s) | PTK2 |
| Structure Name | crystal structure of the focal adhesion targeting domain of focal adhesion kinase |
| Resolution | 2.9Å |
| Reference | AUTH S.T.AROLD,M.K.HOELLERER,M.E.NOBLETITL THE STRUCTURAL BASIS OF LOCALIZATION AND SIGNALINGTITL 2 BY THE FOCAL ADHESION TARGETING DOMAIN.REF STRUCTURE V. 10 319 2002REFN ISSN 0969-2126PMID 12005431DOI 10.1016/S0969-2126(02)00717-7 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 142 |
| Number Of SNVs | 26 |
| Number Of Permutations | 5880 |
| Optimal Distance Threshold | 16.0 |
| K Statistic | 0.271 |
| p-value | 0.103 |
COSMIC
| Number Of Residues | 142 |
| Number Of SNVs | 3 |
| Number Of Permutations | 27 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.333 |
| p-value | 0.634 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 26 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.244 |
| p-value | 0.633 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
