Assessment of Structural Intolerance and Durability
General Structure Information 2i6k IDI1 crystal structure of human type i ipp isomerase complexed with a substrate analog 2.0Å AUTH C.ZHANG,L.LIU,H.XU,Z.WEI,Y.WANG,Y.LIN,W.GONGTITL CRYSTAL STRUCTURES OF HUMAN IPP ISOMERASE: NEWTITL 2 INSIGHTS INTO THE CATALYTIC MECHANISMREF J.MOL.BIOL. V. 366 1437 2007REFN ISSN 0022-2836PMID 17137593DOI 10.1016/J.JMB.2006.10.092 Variant Set Distributions Mapped Variants
General Structure Information 2nxp TAF5 structure of ntd2 domain of the human taf5 subunit of tfiid 2.17Å AUTH S.BHATTACHARYA,S.TAKADA,R.H.JACOBSONTITL STRUCTURAL ANALYSIS AND DIMERIZATION POTENTIAL OFTITL 2 THE HUMAN TAF5 SUBUNIT OF TFIID.REF PROC.NATL.ACAD.SCI.USA V. 104 1189 2007REFN ISSN 0027-8424PMID 17227857DOI 10.1073/PNAS.0610297104 Variant Set Distributions Mapped Variants
General Structure Information 4bl1 MELK crystal structure of unphosphorylated maternal embryonic leucine zipper kinase (melk) in complex with amp-pnp 2.6Å AUTH G.CANEVARI,S.RE-DEPAOLINI,U.CUCCHI,B.FORTE,P.CARPINELLI,AUTH 2 J.A.BERTRANDTITL CRYSTAL STRUCTURE OF UNPHOSPHORYLATED MATERNAL EMBRYONICTITL 2 LEUCINE ZIPPER KINASEREF TO BE PUBLISHED Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2kle PKD2 isic refined solution structure of the calcium binding domain of the c-terminal cytosolic domain of polycystin-2 -1.0Å AUTH F.H.SCHUMANN,H.HOFFMEISTER,M.SCHMIDT,R.BADER,AUTH 2 E.BESL,R.WITZGALL,H.R.KALBITZERTITL NMR-ASSIGNMENTS OF A CYTOSOLIC DOMAIN OF THETITL 2 C-TERMINUS OF POLYCYSTIN-2REF BIOMOL.NMR ASSIGN. V. 3 141 2009REFN ISSN 1874-2718PMID 19636966DOI 10.1007/S12104-009-9160-X Variant Set Distributions Mapped Variants
General Structure Information 4b3z CRMP1 structure of the human collapsin response mediator protein-1, a lung cancer suppressor 3.05Å AUTH S.H.LIU,S.F.HUANG,Y.L.HSU,S.H.PAN,Y.J.CHEN,Y.H.LINTITL STRUCTURE OF HUMAN COLLAPSIN RESPONSE MEDIATOR PROTEIN 1: ATITL 2 POSSIBLE ROLE OF ITS C-TERMINAL TAIL.REF ACTA CRYSTALLOGR.,SECT.F V. 71 938 2015REFN ISSN 1744-3091PMID 26249678DOI 10.1107/S2053230X15009243 Variant Set Distributions Ripley’s K Analysis Plots Variant Set […]
General Structure Information 2bkf NBR1 structure of the pb1 domain of nbr1 1.56Å AUTH S.MUELLER,I.KURSULA,P.ZOU,M.WILMANNSTITL CRYSTAL STRUCTURE OF THE PB1 DOMAIN OF NBR1REF FEBS LETT. V. 580 341 2006REFN ISSN 0014-5793PMID 16376336DOI 10.1016/J.FEBSLET.2005.12.021 Variant Set Distributions Mapped Variants
General Structure Information 2edn MYBPC2 solution structure of the first ig-like domain from human myosin-binding protein c, fast-type -1.0Å AUTH K.NAGASHIMA,C.KUROSAKI,M.YOSHIDA,F.HAYASHI,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FIRST IG-LIKE DOMAINTITL 2 FROM HUMAN MYOSIN-BINDING PROTEIN C, FAST-TYPEREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 1kt0 FKBP5 structure of the large fkbp-like protein, fkbp51, involved in steroid receptor complexes 2.7Å AUTH C.R.SINARS,J.CHEUNG-FLYNN,R.A.RIMERMAN,J.G.SCAMMELL,AUTH 2 D.F.SMITH,J.C.CLARDYTITL STRUCTURE OF THE LARGE FK506-BINDING PROTEIN FKBP51, ANTITL 2 HSP90-BINDING PROTEIN AND A COMPONENT OF STEROID RECEPTORTITL 3 COMPLEXESREF PROC.NATL.ACAD.SCI.USA V. 100 868 2003REFN ISSN 0027-8424PMID 12538866DOI 10.1073/PNAS.0231020100 Variant Set Distributions Ripley’s K […]
General Structure Information 2m85 SHPRH phd domain from human shprh -1.0Å AUTH L.E.MACHADO,Y.PUSTOVALOVA,A.C.KILE,A.POZHIDAEVA,AUTH 2 K.A.CIMPRICH,F.C.ALMEIDA,I.BEZSONOVA,D.M.KORZHNEVTITL PHD DOMAIN FROM HUMAN SHPRH.REF J.BIOMOL.NMR V. 56 393 2013REFN ISSN 0925-2738PMID 23907177DOI 10.1007/S10858-013-9758-2 Variant Set Distributions Mapped Variants
General Structure Information 2jng CUL7 solution structure of the cul7-cph domain from homo sapiens; northeast structural genomics consortium target ht1. -1.0Å AUTH L.KAUSTOV,J.LUKIN,A.LEMAK,S.DUAN,M.HO,R.DOHERTY,AUTH 2 L.Z.PENN,C.H.ARROWSMITHTITL THE CONSERVED CPH DOMAINS OF CUL7 AND PARC ARETITL 2 PROTEIN-PROTEIN INTERACTION MODULES THAT BIND THETITL 3 TETRAMERIZATION DOMAIN OF P53REF J.BIOL.CHEM. V. 282 11300 2007REFN ISSN 0021-9258PMID 17298945DOI 10.1074/JBC.M611297200 […]