General Structure Information
| PDB ID | 1kt0 |
| HGNC Gene Label(s) | FKBP5 |
| Structure Name | structure of the large fkbp-like protein, fkbp51, involved in steroid receptor complexes |
| Resolution | 2.7Å |
| Reference | AUTH C.R.SINARS,J.CHEUNG-FLYNN,R.A.RIMERMAN,J.G.SCAMMELL,AUTH 2 D.F.SMITH,J.C.CLARDYTITL STRUCTURE OF THE LARGE FK506-BINDING PROTEIN FKBP51, ANTITL 2 HSP90-BINDING PROTEIN AND A COMPONENT OF STEROID RECEPTORTITL 3 COMPLEXESREF PROC.NATL.ACAD.SCI.USA V. 100 868 2003REFN ISSN 0027-8424PMID 12538866DOI 10.1073/PNAS.0231020100 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 357 |
| Number Of SNVs | 70 |
| Number Of Permutations | 21378 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.017 |
| p-value | 0.175 |
COSMIC
| Number Of Residues | 357 |
| Number Of SNVs | 7 |
| Number Of Permutations | 7070 |
| Optimal Distance Threshold | 28.0 |
| K Statistic | 0.095 |
| p-value | 0.008 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 70 |
| Number Of COSMIC SNVs | 5 |
| Optimal Distance Threshold | 28.0 |
| K Statistic | -0.342 |
| p-value | 0.007 |