Assessment of Structural Intolerance and Durability
General Structure Information 3dju BTG2 crystal structure of human btg2 2.26Å AUTH X.YANG,M.MORITA,H.WANG,T.SUZUKI,W.YANG,Y.LUO,AUTH 2 C.ZHAO,Y.YU,M.BARTLAM,T.YAMAMOTO,Z.RAOTITL CRYSTAL STRUCTURES OF HUMAN BTG2 AND MOUSE TIS21TITL 2 INVOLVED IN SUPPRESSION OF CAF1 DEADENYLASETITL 3 ACTIVITYREF NUCLEIC ACIDS RES. V. 36 6872 2008REFN ISSN 0305-1048PMID 18974182DOI 10.1093/NAR/GKN825 Variant Set Distributions Mapped Variants
General Structure Information 1u7f SMAD3 crystal structure of the phosphorylated smad3/smad4 heterotrimeric complex 2.6Å AUTH B.M.CHACKO,B.Y.QIN,A.TIWARI,G.SHI,S.LAM,AUTH 2 L.J.HAYWARD,M.DE CAESTECKER,K.LINTITL STRUCTURAL BASIS OF HETEROMERIC SMAD PROTEINTITL 2 ASSEMBLY IN TGF-BETA SIGNALINGREF MOL.CELL V. 15 813 2004REFN ISSN 1097-2765PMID 15350224DOI 10.1016/J.MOLCEL.2004.07.016 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2ctm HDLBP solution structure of the 14th kh type i domain from human vigilin -1.0Å AUTH T.TOMIZAWA,T.KIGAWA,S.KOSHIBA,M.INOUE,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE 14TH KH TYPE I DOMAINTITL 2 FROM HUMAN VIGILINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1foe RAC1 crystal structure of rac1 in complex with the guanine nucleotide exchange region of tiam1 2.8Å AUTH D.K.WORTHYLAKE,K.L.ROSSMAN,J.SONDEKTITL CRYSTAL STRUCTURE OF RAC1 IN COMPLEX WITH THETITL 2 GUANINE NUCLEOTIDE EXCHANGE REGION OF TIAM1.REF NATURE V. 408 682 2000REFN ISSN 0028-0836PMID 11130063DOI 10.1038/35047014 Variant Set Distributions Ripley’s K Analysis Plots Variant Set […]
General Structure Information 1aa2 SPTBN1 calponin homology (ch) domain from human beta-spectrin 2.0Å AUTH K.DJINOVIC CARUGO,S.BANUELOS,M.SARASTETITL CRYSTAL STRUCTURE OF A CALPONIN HOMOLOGY DOMAIN.REF NAT.STRUCT.BIOL. V. 4 175 1997REFN ISSN 1072-8368PMID 9164454DOI 10.1038/NSB0397-175 Variant Set Distributions Mapped Variants
General Structure Information 2hci CCL20 structure of human mip-3a chemokine 1.81Å AUTH Z.A.MALIK,B.F.TACKTITL STRUCTURE OF HUMAN MIP-3ALPHA CHEMOKINE.REF ACTA CRYSTALLOGR.,SECT.F V. 62 631 2006REFN ESSN 1744-3091PMID 16820679DOI 10.1107/S1744309106006890 Variant Set Distributions Mapped Variants
General Structure Information 3vln GSTO1 human glutathione transferase o1-1 c32s mutant in complex with ascorbic acid 1.7Å AUTH H.ZHOU,J.BROCK,D.LIU,P.G.BOARD,A.J.OAKLEYTITL STRUCTURAL INSIGHTS INTO THE DEHYDROASCORBATE REDUCTASETITL 2 ACTIVITY OF HUMAN OMEGA-CLASS GLUTATHIONE TRANSFERASES.REF J.MOL.BIOL. V. 420 190 2012REFN ISSN 0022-2836PMID 22522127DOI 10.1016/J.JMB.2012.04.014 Variant Set Distributions Mapped Variants
General Structure Information 2gzd RAB11A crystal structure of rab11 in complex with rab11-fip2 2.44Å AUTH W.N.JAGOE,A.J.LINDSAY,R.J.READ,A.J.MCCOY,AUTH 2 M.W.MCCAFFREY,A.R.KHANTITL CRYSTAL STRUCTURE OF RAB11 IN COMPLEX WITH RAB11TITL 2 FAMILY INTERACTING PROTEIN 2.REF STRUCTURE V. 14 1273 2006REFN ISSN 0969-2126PMID 16905101DOI 10.1016/J.STR.2006.06.010 Variant Set Distributions Mapped Variants
General Structure Information 1ypo OLR1 human oxidized low density lipoprotein receptor lox-1 p3 1 21 space group 3.0Å AUTH H.PARK,F.G.ADSIT,J.C.BOYINGTONTITL THE 1.4 ANGSTROM CRYSTAL STRUCTURE OF THE HUMANTITL 2 OXIDIZED LOW DENSITY LIPOPROTEIN RECEPTOR LOX-1.REF J.BIOL.CHEM. V. 280 13593 2005REFN ISSN 0021-9258PMID 15695803DOI 10.1074/JBC.M500768200 Variant Set Distributions Mapped Variants
General Structure Information 2c47 CSNK1G2 structure of casein kinase 1 gamma 2 2.4Å AUTH G.BUNKOCZI,P.RELLOS,S.DAS,E.UGOCHUKWU,O.FEDOROV,F.SOBOTT,AUTH 2 J.ESWARAN,A.AMOS,L.BALL,F.VON DELFT,A.BULLOCK,J.DEBRECZENI,AUTH 3 A.TURNBULL,M.SUNDSTROM,J.WEIGELT,C.ARROWSMITH,A.EDWARDS,AUTH 4 S.KNAPPTITL THE STRUCTURE OF CASEIN KINASE 1 GAMMA 2REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants