Assessment of Structural Intolerance and Durability
General Structure Information 3eu9 ZDHHC17 the ankyrin repeat domain of huntingtin interacting protein 14 1.99Å AUTH T.GAO,R.E.COLLINS,J.R.HORTON,X.ZHANG,R.ZHANG,A.DHAYALAN,AUTH 2 R.TAMAS,A.JELTSCH,X.CHENGTITL THE ANKYRIN REPEAT DOMAIN OF HUNTINGTIN INTERACTING PROTEINTITL 2 14 CONTAINS A SURFACE AROMATIC CAGE, A POTENTIAL SITE FORTITL 3 METHYL-LYSINE BINDING.REF PROTEINS V. 76 772 2009REFN ISSN 0887-3585PMID 19434754DOI 10.1002/PROT.22452 Variant Set Distributions Mapped Variants
General Structure Information 3b76 LNX1 crystal structure of the third pdz domain of human ligand-of-numb protein-x (lnx1) in complex with the c-terminal peptide from the coxsackievirus and adenovirus receptor 1.75Å AUTH E.UGOCHUKWU,N.BURGESS-BROWN,G.BERRIDGE,J.ELKINS,G.BUNKOCZI,AUTH 2 A.C.W.PIKE,M.SUNDSTROM,C.H.ARROWSMITH,J.WEIGELT,A.M.EDWARDS,AUTH 3 O.GILEADI,F.VON DELFT,D.DOYLETITL CRYSTAL STRUCTURE OF THE THIRD PDZ DOMAIN OF HUMANTITL 2 LIGAND-OF-NUMB PROTEIN-X (LNX1) IN COMPLEX WITH THETITL 3 […]
General Structure Information 3l11 RNF168 crystal structure of the ring domain of rnf168 2.12Å AUTH S.J.CAMPBELL,R.A.EDWARDS,C.C.LEUNG,D.NECULAI,C.D.HODGE,AUTH 2 S.DHE-PAGANON,J.N.GLOVERTITL MOLECULAR INSIGHTS INTO THE FUNCTION OF RING FINGERTITL 2 (RNF)-CONTAINING PROTEINS HRNF8 AND HRNF168 INTITL 3 UBC13/MMS2-DEPENDENT UBIQUITYLATION.REF J.BIOL.CHEM. V. 287 23900 2012REFN ISSN 0021-9258PMID 22589545DOI 10.1074/JBC.M112.359653 Variant Set Distributions Mapped Variants
General Structure Information 2uzg USP33 zf-ubp domain of vdu1 -1.0Å AUTH M.D.ALLEN,M.BYCROFTTITL THE SOLUTION STRUCTURE OF THE ZNF UBP DOMAIN OFTITL 2 USP33/VDU1.REF PROTEIN SCI. V. 16 2072 2007REFN ISSN 0961-8368PMID 17766394DOI 10.1110/PS.072967807 Variant Set Distributions Mapped Variants
General Structure Information 4hpl BCOR pcgf1 ub fold (rawul)/bcor pufd complex 2.0Å AUTH S.E.JUNCO,R.WANG,J.C.GAIPA,A.B.TAYLOR,V.SCHIRF,M.D.GEARHART,AUTH 2 V.J.BARDWELL,B.DEMELER,P.J.HART,C.A.KIMTITL STRUCTURE OF THE POLYCOMB GROUP PROTEIN PCGF1 IN COMPLEXTITL 2 WITH BCOR REVEALS BASIS FOR BINDING SELECTIVITY OF PCGFTITL 3 HOMOLOGS.REF STRUCTURE V. 21 665 2013REFN ISSN 0969-2126PMID 23523425DOI 10.1016/J.STR.2013.02.013 Variant Set Distributions Ripley’s K Analysis Plots Variant Set […]
General Structure Information 3kv4 H3F3C structure of phf8 in complex with histone h3 2.19Å AUTH J.R.HORTON,A.K.UPADHYAY,H.H.QI,X.ZHANG,Y.SHI,AUTH 2 X.CHENGTITL ENZYMATIC AND STRUCTURAL INSIGHTS FOR SUBSTRATETITL 2 SPECIFICITY OF A FAMILY OF JUMONJI HISTONE LYSINETITL 3 DEMETHYLASES.REF NAT.STRUCT.MOL.BIOL. V. 17 38 2010REFN ISSN 1545-9993PMID 20023638DOI 10.1038/NSMB.1753 Variant Set Distributions Mapped Variants
General Structure Information 2rpp MBNL2 solution structure of tandem zinc finger domain 12 in muscleblind-like protein 2 -1.0Å AUTH F.HE,W.DANG,C.ABE,K.TSUDA,M.INOUE,S.WATANABE,AUTH 2 N.KOBAYASHI,T.KIGAWA,T.MATSUDA,T.YABUKI,M.AOKI,AUTH 3 E.SEKI,T.HARADA,Y.TOMABECHI,T.TERADA,M.SHIROUZU,AUTH 4 A.TANAKA,P.GUNTERT,Y.MUTO,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE RNA BINDING DOMAIN INTITL 2 THE HUMAN MUSCLEBLIND-LIKE PROTEIN 2REF PROTEIN SCI. V. 18 80 2009REFN ISSN 0961-8368PMID 19177353DOI 10.1002/PRO.17 Variant Set Distributions Mapped Variants
General Structure Information 4hpm BCORL1 pcgf1 ub fold (rawul)/bcorl1 pufd complex 1.85Å AUTH S.E.JUNCO,R.WANG,J.C.GAIPA,A.B.TAYLOR,V.SCHIRF,M.D.GEARHART,AUTH 2 V.J.BARDWELL,B.DEMELER,P.J.HART,C.A.KIMTITL STRUCTURE OF THE POLYCOMB GROUP PROTEIN PCGF1 IN COMPLEXTITL 2 WITH BCOR REVEALS BASIS FOR BINDING SELECTIVITY OF PCGFTITL 3 HOMOLOGS.REF STRUCTURE V. 21 665 2013REFN ISSN 0969-2126PMID 23523425DOI 10.1016/J.STR.2013.02.013 Variant Set Distributions Ripley’s K Analysis Plots Variant Set […]
General Structure Information 3kv5 KDM7A structure of kiaa1718, human jumonji demethylase, in complex with n-oxalylglycine 2.39Å AUTH J.R.HORTON,A.K.UPADHYAY,H.H.QI,X.ZHANG,Y.SHI,AUTH 2 X.CHENGTITL ENZYMATIC AND STRUCTURAL INSIGHTS FOR SUBSTRATETITL 2 SPECIFICITY OF A FAMILY OF JUMONJI HISTONE LYSINETITL 3 DEMETHYLASES.REF NAT.STRUCT.MOL.BIOL. V. 17 38 2010REFN ISSN 1545-9993PMID 20023638DOI 10.1038/NSMB.1753 Variant Set Distributions Ripley’s K Analysis Plots Variant Set […]
General Structure Information 2c52 NCOA1 structural diversity in cbp p160 complexes -1.0Å AUTH L.C.WATERS,B.YUE,V.VEVERKA,P.S.RENSHAW,J.BRAMHAM,AUTH 2 S.MATSUDA,T.FRENKIEL,G.KELLY,F.W.MUSKETT,M.D.CARR,AUTH 3 D.M.HEERYTITL STRUCTURAL DIVERSITY IN P160/CREB-BINDING PROTEINTITL 2 COACTIVATOR COMPLEXES.REF J.BIOL.CHEM. V. 281 14787 2006REFN ISSN 0021-9258PMID 16540468DOI 10.1074/JBC.M600237200 Variant Set Distributions Mapped Variants