General Structure Information
| PDB ID | 3kv5 |
| HGNC Gene Label(s) | KDM7A |
| Structure Name | structure of kiaa1718, human jumonji demethylase, in complex with n-oxalylglycine |
| Resolution | 2.39Å |
| Reference | AUTH J.R.HORTON,A.K.UPADHYAY,H.H.QI,X.ZHANG,Y.SHI,AUTH 2 X.CHENGTITL ENZYMATIC AND STRUCTURAL INSIGHTS FOR SUBSTRATETITL 2 SPECIFICITY OF A FAMILY OF JUMONJI HISTONE LYSINETITL 3 DEMETHYLASES.REF NAT.STRUCT.MOL.BIOL. V. 17 38 2010REFN ISSN 1545-9993PMID 20023638DOI 10.1038/NSMB.1753 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 445 |
| Number Of SNVs | 67 |
| Number Of Permutations | 22790 |
| Optimal Distance Threshold | 27.0 |
| K Statistic | 0.306 |
| p-value | 0.016 |
COSMIC
| Number Of Residues | 445 |
| Number Of SNVs | 5 |
| Number Of Permutations | 453 |
| Optimal Distance Threshold | 24.0 |
| K Statistic | 0.4 |
| p-value | 0.862 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 67 |
| Number Of COSMIC SNVs | 5 |
| Optimal Distance Threshold | 41.0 |
| K Statistic | 0.25 |
| p-value | 0.454 |