2C5L.D | PLCE1

General Structure Information 2c5l PLCE1 structure of plc epsilon ras association domain with hras 1.9Å AUTH T.D.BUNNEY,R.HARRIS,N.L.GANDARILLAS,M.B.JOSEPHS,AUTH 2 S.M.ROE,S.C.SORLI,H.F.PATERSON,F.RODRIGUES-LIMA,AUTH 3 D.ESPOSITO,C.P.PONTING,P.GIESCHIK,L.H.PEARL,AUTH 4 P.C.DRISCOLL,M.KATANTITL STRUCTURAL AND MECHANISTIC INSIGHTS INTO RASTITL 2 ASSOCIATION DOMAINS OF PHOSPHOLIPASE C EPSILONREF MOL.CELL V. 21 495 2006REFN ISSN 1097-2765PMID 16483931DOI 10.1016/J.MOLCEL.2006.01.008 Variant Set Distributions Mapped Variants

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3O65.A | ATXN3L

General Structure Information 3o65 ATXN3L crystal structure of a josephin-ubiquitin complex: evolutionary restraints on ataxin-3 deubiquitinating activity 2.7Å AUTH S.D.WEEKS,K.C.GRASTY,L.HERNANDEZ-CUEBAS,P.J.LOLLTITL CRYSTAL STRUCTURE OF A JOSEPHIN-UBIQUITIN COMPLEX:TITL 2 EVOLUTIONARY RESTRAINTS ON ATAXIN-3 DEUBIQUITINATINGTITL 3 ACTIVITY.REF J.BIOL.CHEM. V. 286 4555 2011REFN ISSN 0021-9258PMID 21118805DOI 10.1074/JBC.M110.177360 Variant Set Distributions Mapped Variants

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3EGA.A | PELI2

General Structure Information 3ega PELI2 crystal structure of pellino2 fha domain at 1.8 angstroms resolution 1.8Å AUTH C.C.LIN,Y.S.HUOH,K.R.SCHMITZ,L.E.JENSEN,K.M.FERGUSONTITL PELLINO PROTEINS CONTAIN A CRYPTIC FHA DOMAIN THAT MEDIATESTITL 2 INTERACTION WITH PHOSPHORYLATED IRAK1.REF STRUCTURE V. 16 1806 2008REFN ISSN 0969-2126PMID 19081057DOI 10.1016/J.STR.2008.09.011 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped […]

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2JQZ.A | SMURF2

General Structure Information 2jqz SMURF2 solution structure of the c2 domain of human smurf2 -1.0Å AUTH S.WIESNER,A.A.OGUNJIMI,H.-R.WANG,D.ROTIN,F.SICHERI,AUTH 2 J.L.WRANA,J.D.FORMAN-KAYTITL AUTOINHIBITION OF THE HECT-TYPE UBIQUITIN LIGASETITL 2 SMURF2 THROUGH ITS C2 DOMAINREF CELL(CAMBRIDGE,MASS.) V. 130 651 2007REFN ISSN 0092-8674PMID 17719543DOI 10.1016/J.CELL.2007.06.050 Variant Set Distributions Mapped Variants

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2IO1.C | SENP2

General Structure Information 2io1 SENP2 crystal structure of human senp2 in complex with presumo-3 2.6Å AUTH D.REVERTER,C.D.LIMATITL STRUCTURAL BASIS FOR SENP2 PROTEASE INTERACTIONSTITL 2 WITH SUMO PRECURSORS AND CONJUGATED SUBSTRATES.REF NAT.STRUCT.MOL.BIOL. V. 13 1060 2006REFN ISSN 1545-9993PMID 17099700DOI 10.1038/NSMB1168 Variant Set Distributions Mapped Variants

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2VHF.B | CYLD

General Structure Information 2vhf CYLD structure of the cyld usp domain 2.8Å AUTH D.KOMANDER,C.J.LORD,H.SCHEEL,S.SWIFT,K.HOFMANN,AUTH 2 A.ASHWORTH,D.BARFORDTITL THE STRUCTURE OF THE CYLD USP DOMAIN EXPLAINS ITSTITL 2 SPECIFICITY FOR LYS63-LINKED POLYUBIQUITIN ANDTITL 3 REVEALS A B-BOX MODULEREF MOL.CELL.BIOL. V. 29 451 2008REFN ISSN 0270-7306PMID 18313383DOI 10.1016/J.MOLCEL.2007.12.018 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons […]

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1ZVD.A | SMURF2

General Structure Information 1zvd SMURF2 regulation of smurf2 ubiquitin ligase activity by anchoring the e2 to the hect domain 2.1Å AUTH A.A.OGUNJIMI,D.J.BRIANT,N.PECE-BARBARA,C.LE ROY,AUTH 2 G.M.DI GUGLIELMO,P.KAVSAK,R.K.RASMUSSEN,B.T.SEET,F.SICHERI,AUTH 3 J.L.WRANATITL REGULATION OF SMURF2 UBIQUITIN LIGASE ACTIVITY BY ANCHORINGTITL 2 THE E2 TO THE HECT DOMAIN.REF MOL.CELL V. 19 297 2005REFN ISSN 1097-2765PMID 16061177DOI 10.1016/J.MOLCEL.2005.06.028 Variant Set Distributions […]

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3HVE.A | GAN

General Structure Information 3hve GAN structures of spop-substrate complexes: insights into molecular architectures of btb-cul3 ubiquitin ligases: gigaxoninbtb/3-box 2.8Å AUTH M.ZHUANG,M.F.CALABRESE,J.LIU,M.B.WADDELL,A.NOURSE,AUTH 2 M.HAMMEL,D.J.MILLER,H.WALDEN,D.M.DUDA,S.N.SEYEDIN,AUTH 3 T.HOGGARD,J.W.HARPER,K.P.WHITE,B.A.SCHULMANTITL STRUCTURES OF SPOP-SUBSTRATE COMPLEXES: INSIGHTSTITL 2 INTO MOLECULAR ARCHITECTURES OF BTB-CUL3 UBIQUITINTITL 3 LIGASES.REF MOL.CELL V. 36 39 2009REFN ISSN 1097-2765PMID 19818708DOI 10.1016/J.MOLCEL.2009.09.022 Variant Set Distributions Ripley’s K Analysis Plots […]

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3OBQ.A | TSG101

General Structure Information 3obq TSG101 crystal structure of the tsg101 uev domain in complex with a human hrs psap peptide 1.4Å AUTH Y.J.IM,L.KUO,X.REN,P.V.BURGOS,X.Z.ZHAO,F.LIU,T.R.BURKE,AUTH 2 J.S.BONIFACINO,E.O.FREED,J.H.HURLEYTITL CRYSTALLOGRAPHIC AND FUNCTIONAL ANALYSIS OF THE ESCRT-ITITL 2 /HIV-1 GAG PTAP INTERACTION.REF STRUCTURE V. 18 1536 2010REFN ISSN 0969-2126PMID 21070952DOI 10.1016/J.STR.2010.08.010 Variant Set Distributions Mapped Variants

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3RPG.C | RNF2

General Structure Information 3rpg RNF2 bmi1/ring1b-ubch5c complex structure 2.65Å AUTH M.L.BENTLEY,J.E.CORN,K.C.DONG,Q.PHUNG,T.K.CHEUNG,A.G.COCHRANTITL RECOGNITION OF UBCH5C AND THE NUCLEOSOME BY THE BMI1/RING1BTITL 2 UBIQUITIN LIGASE COMPLEX.REF EMBO J. V. 30 3285 2011REFN ISSN 0261-4189PMID 21772249DOI 10.1038/EMBOJ.2011.243 Variant Set Distributions Mapped Variants

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