Assessment of Structural Intolerance and Durability
General Structure Information 1uch UCHL3 deubiquitinating enzyme uch-l3 (human) at 1.8 angstrom resolution 1.8Å AUTH S.C.JOHNSTON,C.N.LARSEN,W.J.COOK,K.D.WILKINSON,AUTH 2 C.P.HILLTITL CRYSTAL STRUCTURE OF A DEUBIQUITINATING ENZYMETITL 2 (HUMAN UCH-L3) AT 1.8 A RESOLUTION.REF EMBO J. V. 16 3787 1997REFN ISSN 0261-4189PMID 9233788DOI 10.1093/EMBOJ/16.13.3787 Variant Set Distributions Mapped Variants
General Structure Information 2y5b UBB structure of usp21 in complex with linear diubiquitin-aldehyde 2.7Å AUTH Y.YE,M.AKUTSU,F.REYES-TURCU,R.I.ENCHEV,K.D.WILKINSON,AUTH 2 D.KOMANDERTITL POLYUBIQUITIN BINDING AND CROSS-REACTIVITY IN THE USPTITL 2 DOMAIN DEUBIQUITINASE USP21.REF EMBO REP. V. 12 350 2011REFN ISSN 1469-221XPMID 21399617DOI 10.1038/EMBOR.2011.17 Variant Set Distributions Mapped Variants
General Structure Information 4chb KLHL2 crystal structure of the human klhl2 kelch domain in complex with a wnk4 peptide 1.56Å AUTH F.SCHUMACHER,F.J.SORRELL,D.R.ALESSI,A.N.BULLOCK,T.KURZTITL STRUCTURAL AND BIOCHEMICAL CHARACTERISATION OF THE KLHL3-TITL 2 WNK KINASE INTERACTION IMPORTANT IN BLOOD PRESSURETITL 3 REGULATION.REF BIOCHEM.J. V. 460 237 2014REFN ISSN 0264-6021PMID 24641320DOI 10.1042/BJ20140153 Variant Set Distributions Ripley’s K Analysis Plots […]
General Structure Information 3v6c USP2 crystal structure of usp2 in complex with mutated ubiquitin 1.7Å AUTH M.NECULAI,A.ERNST,S.SIDHU,C.H.ARROWSMITH,A.M.EDWARDS,AUTH 2 C.BOUNTRA,J.WEIGELT,S.DHE-PAGANONTITL CRYSTAL STRUCTURE OF USP2 IN COMPLEX WITH MUTATED UBIQUITINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3hu6 SPOP structures of spop-substrate complexes: insights into molecular architectures of btb-cul3 ubiquitin ligases: spopmathx/btb/3-box-pucsbc1 2.7Å AUTH M.ZHUANG,M.F.CALABRESE,J.LIU,M.B.WADDELL,A.NOURSE,AUTH 2 M.HAMMEL,D.J.MILLER,H.WALDEN,D.M.DUDA,S.N.SEYEDIN,AUTH 3 T.HOGGARD,J.W.HARPER,K.P.WHITE,B.A.SCHULMANTITL STRUCTURES OF SPOP-SUBSTRATE COMPLEXES: INSIGHTSTITL 2 INTO MOLECULAR ARCHITECTURES OF BTB-CUL3 UBIQUITINTITL 3 LIGASES.REF MOL.CELL V. 36 39 2009REFN ISSN 1097-2765PMID 19818708DOI 10.1016/J.MOLCEL.2009.09.022 Variant Set Distributions Ripley’s K Analysis Plots […]
General Structure Information 2l0t STAM2 solution structure of the complex of ubiquitin and the vhs domain of stam2 -1.0Å AUTH A.LANGE,D.HOELLER,H.WIENK,O.MARCILLAT,J.M.LANCELIN,O.WALKERTITL NMR REVEALS A DIFFERENT MODE OF BINDING OF THE STAM2 VHSTITL 2 DOMAIN TO UBIQUITIN AND DIUBIQUITIN.REF BIOCHEMISTRY V. 50 48 2011REFN ISSN 0006-2960PMID 21121635DOI 10.1021/BI101594A Variant Set Distributions Ripley’s K Analysis Plots Variant […]
General Structure Information 3f1i HGS human escrt-0 core complex 2.3Å AUTH X.REN,D.P.KLOER,Y.C.KIM,R.GHIRLANDO,L.F.SAIDI,G.HUMMER,AUTH 2 J.H.HURLEYTITL HYBRID STRUCTURAL MODEL OF THE COMPLETE HUMAN ESCRT-0TITL 2 COMPLEX.REF STRUCTURE V. 17 406 2009REFN ISSN 0969-2126PMID 19278655DOI 10.1016/J.STR.2009.01.012 Variant Set Distributions Mapped Variants
General Structure Information 1wzv UBE2L6 crystal structure of ubch8 2.1Å AUTH T.MIZUSHIMA,M.SUZUKI,N.TESHIMA,T.YAMANE,S.MURATA,AUTH 2 K.TANAKATITL CRYSTAL STRUCTURE OF UBCH8REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants