General Structure Information
| PDB ID | 1zvd |
| HGNC Gene Label(s) | SMURF2 |
| Structure Name | regulation of smurf2 ubiquitin ligase activity by anchoring the e2 to the hect domain |
| Resolution | 2.1Å |
| Reference | AUTH A.A.OGUNJIMI,D.J.BRIANT,N.PECE-BARBARA,C.LE ROY,AUTH 2 G.M.DI GUGLIELMO,P.KAVSAK,R.K.RASMUSSEN,B.T.SEET,F.SICHERI,AUTH 3 J.L.WRANATITL REGULATION OF SMURF2 UBIQUITIN LIGASE ACTIVITY BY ANCHORINGTITL 2 THE E2 TO THE HECT DOMAIN.REF MOL.CELL V. 19 297 2005REFN ISSN 1097-2765PMID 16061177DOI 10.1016/J.MOLCEL.2005.06.028 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 366 |
| Number Of SNVs | 46 |
| Number Of Permutations | 32615 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.007 |
| p-value | 0.351 |
COSMIC
| Number Of Residues | 366 |
| Number Of SNVs | 3 |
| Number Of Permutations | 1 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.333 |
| p-value | 1.0 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
