Assessment of Structural Intolerance and Durability
General Structure Information 1z0i RAB21 gdp-bound rab21 gtpase 2.33Å AUTH S.EATHIRAJ,X.PAN,C.RITACCO,D.G.LAMBRIGHTTITL STRUCTURAL BASIS OF FAMILY-WIDE RAB GTPASETITL 2 RECOGNITION BY RABENOSYN-5.REF NATURE V. 436 415 2005REFN ISSN 0028-0836PMID 16034420DOI 10.1038/NATURE03798 Variant Set Distributions Mapped Variants
General Structure Information 1ujk GGA1 vhs domain of human gga1 complexed with c-terminal phosphopeptide from bace 1.9Å AUTH T.SHIBA,S.KAMETAKA,M.KAWASAKI,M.SHIBATA,S.WAGURI,AUTH 2 Y.UCHIYAMA,S.WAKATSUKITITL INSIGHTS INTO THE PHOSPHOREGULATION OFTITL 2 BETA-SECRETASE SORTING SIGNAL BY THE VHS DOMAIN OFTITL 3 GGA1REF TRAFFIC V. 5 437 2004REFN ISSN 1398-9219PMID 15117318DOI 10.1111/J.1600-0854.2004.00188.X Variant Set Distributions Mapped Variants
General Structure Information 4ae4 UBAP1 the ubap1 subunit of escrt-i interacts with ubiquitin via a novel souba domain 1.65Å AUTH M.AGROMAYOR,N.SOLER,A.CABALLE,T.KUECK,S.M.FREUND,M.D.ALLEN,AUTH 2 M.BYCROFT,O.PERISIC,Y.YE,B.MCDONALD,H.SCHEEL,K.HOFMANN,AUTH 3 S.J.D.NEIL,J.MARTIN-SERRANO,R.L.WILLIAMSTITL THE UBAP1 SUBUNIT OF ESCRT-I INTERACTS WITH UBIQUITIN VIA ATITL 2 SOUBA DOMAIN.REF STRUCTURE V. 20 414 2012REFN ISSN 0969-2126PMID 22405001DOI 10.1016/J.STR.2011.12.013 Variant Set Distributions Mapped Variants
General Structure Information 2csk SNX12 solution structure of px domain from human snx12 -1.0Å AUTH T.SUETAKE,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF PX DOMAIN FROM HUMAN SNX12REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3nhb ABCB6 nucleotide binding domain of human abcb6 (adp bound structure) 2.15Å AUTH M.HAFFKE,A.MENZEL,Y.CARIUS,D.JAHN,D.W.HEINZTITL STRUCTURES OF THE NUCLEOTIDE-BINDING DOMAIN OF THE HUMANTITL 2 ABCB6 TRANSPORTER AND ITS COMPLEXES WITH NUCLEOTIDES.REF ACTA CRYSTALLOGR.,SECT.D V. 66 979 2010REFN ISSN 0907-4449PMID 20823549DOI 10.1107/S0907444910028593 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity […]
General Structure Information 2hz5 DYNLRB1 crystal structure of human dynein light chain dnlc2a 2.1Å AUTH J.-F.LIU,Z.-X.WANG,X.-Q.WANG,Q.TANG,X.-M.AN,L.-L.GUI,AUTH 2 D.-C.LIANGTITL CRYSTAL STRUCTURE OF HUMAN DYNEIN LIGHT CHAIN DNLC2A:TITL 2 STRUCTURAL INSIGHTS INTO THE INTERACTION WITH IC74REF BIOCHEM.BIOPHYS.RES.COMMUN. V. 349 1125 2006REFN ISSN 0006-291XPMID 16970917DOI 10.1016/J.BBRC.2006.08.161 Variant Set Distributions Mapped Variants
General Structure Information 4dhx ENY2 eny2:ganp complex 2.1Å AUTH D.JANI,S.LUTZ,E.HURT,R.A.LASKEY,M.STEWART,V.O.WICKRAMASINGHETITL FUNCTIONAL AND STRUCTURAL CHARACTERIZATION OF THE MAMMALIANTITL 2 TREX-2 COMPLEX THAT LINKS TRANSCRIPTION WITH NUCLEARTITL 3 MESSENGER RNA EXPORT.REF NUCLEIC ACIDS RES. V. 40 4562 2012REFN ISSN 0305-1048PMID 22307388DOI 10.1093/NAR/GKS059 Variant Set Distributions Mapped Variants
General Structure Information 2ocb RAB9B crystal structure of human rab9b in complex with a gtp analogue 2.2Å AUTH B.HONG,L.SHEN,J.R.WALKER,W.TEMPEL,R.LANDRY,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,M.SUNDSTROM,J.WEIGELT,AUTH 3 A.BOCHKAREV,H.PARKTITL CRYSTAL STRUCTURE OF HUMAN RAB9B IN COMPLEX WITH ATITL 2 GTP ANALOGUEREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 4iy4 CNNM2 structural and ligand binding properties of the bateman domain of human magnesium transporters cnnm2 and cnnm4 2.9Å AUTH M.A.CORRAL-RODRIGUEZ,M.STUIVER,J.A.ENCINAR,V.SPIWOK,AUTH 2 I.GOMEZ-GARCIA,I.OYENARTE,J.ERENO-ORBEA,H.TERASHIMA,AUTH 3 A.ACCARDI,T.DIERCKS,D.MULLER,L.A.MARTINEZ-CRUZTITL STRUCTURAL AND LIGAND BINDING PROPERTIES OF THE BATEMANTITL 2 DOMAIN OF HUMAN MAGNESIUM TRANSPORTERS CNNM2 AND CNNM4REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 4i9w KCNK4 human two pore domain k+ channel traak (k2p4.1) – fab complex structure 2.75Å AUTH S.G.BROHAWN,E.B.CAMPBELL,R.MACKINNONTITL DOMAIN-SWAPPED CHAIN CONNECTIVITY AND GATED MEMBRANE ACCESSTITL 2 IN A FAB-MEDIATED CRYSTAL OF THE HUMAN TRAAK K+ CHANNEL.REF PROC.NATL.ACAD.SCI.USA V. 110 2129 2013REFN ISSN 0027-8424PMID 23341632DOI 10.1073/PNAS.1218950110 Variant Set Distributions Mapped Variants