Assessment of Structural Intolerance and Durability
General Structure Information 4hhv COL4A3BP crystal structure of ceramide transfer protein pleckstrin homology domain 1.75Å AUTH J.PRASHEK,T.TRUONG,X.YAOTITL CRYSTAL STRUCTURE OF THE PLECKSTRIN HOMOLOGY DOMAIN FROM THETITL 2 CERAMIDE TRANSFER PROTEIN: IMPLICATIONS FOR CONFORMATIONALTITL 3 CHANGE UPON LIGAND BINDING.REF PLOS ONE V. 8 79590 2013REFN ESSN 1932-6203PMID 24260258DOI 10.1371/JOURNAL.PONE.0079590 Variant Set Distributions Mapped Variants
General Structure Information 3h3s COL4A3BP crystal structure of the cert start domain in complex with hpa-15 1.66Å AUTH N.KUDO,K.KUMAGAI,R.MATSUBARA,S.KOBAYASHI,K.HANADA,AUTH 2 S.WAKATSUKI,R.KATOTITL CRYSTAL STRUCTURES OF THE CERT START DOMAIN WITHTITL 2 INHIBITORS PROVIDE INSIGHTS INTO THE MECHANISM OFTITL 3 CERAMIDE TRANSFER.REF J.MOL.BIOL. V. 396 245 2010REFN ISSN 0022-2836PMID 20036255DOI 10.1016/J.JMB.2009.12.029 Variant Set Distributions Ripley’s K Analysis […]
General Structure Information 1r4x COPG1 crystal structure analys of the gamma-copi appendage domain 1.9Å AUTH P.J.WATSON,G.FRIGERIO,B.M.COLLINS,R.DUDEN,D.J.OWENTITL GAMMA-COP APPENDAGE DOMAIN – STRUCTURE AND FUNCTIONREF TRAFFIC V. 5 79 2004REFN ISSN 1398-9219PMID 14690497DOI 10.1111/J.1600-0854.2004.00158.X Variant Set Distributions Mapped Variants
General Structure Information 4ikd SNX11 crystal structure of snx11 px domain 1.6Å AUTH J.XU,T.XU,J.LIUTITL STRUCTURE OF SORTING NEXIN 11 (SNX11) REVEALS A NOVELTITL 2 EXTENDED PX DOMAIN (PXE DOMAIN) CRITICAL FOR THE INHIBITIONTITL 3 OF SORTING NEXIN 10 (SNX10) INDUCED VACUOLATIONREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1jo6 KCNMB2 solution structure of the cytoplasmic n-terminus of the bk beta-subunit kcnmb2 -1.0Å AUTH D.BENTROP,M.BEYERMANN,R.WISSMANN,B.FAKLERTITL NMR STRUCTURE OF THE BALL-AND-CHAIN DOMAIN OFTITL 2 KCNMB2, THE BETA 2-SUBUNIT OF LARGE CONDUCTANCETITL 3 CA2+- AND VOLTAGE-ACTIVATED POTASSIUM CHANNELS.REF J.BIOL.CHEM. V. 276 42116 2001REFN ISSN 0021-9258PMID 11517232DOI 10.1074/JBC.M107118200 Variant Set Distributions Mapped Variants
General Structure Information 2zmv TRAPPC4 crystal structure of synbindin 2.8Å AUTH S.FAN,Z.WEI,H.XU,W.GONGTITL CRYSTAL STRUCTURE OF HUMAN SYNBINDIN REVEALS TWOTITL 2 CONFORMATIONS OF LONGIN DOMAINREF BIOCHEM.BIOPHYS.RES.COMMUN. V. 378 338 2009REFN ISSN 0006-291XPMID 18466758DOI 10.1016/J.BBRC.2008.04.143 Variant Set Distributions Mapped Variants
General Structure Information 3ex7 RBM8A the crystal structure of ejc in its transition state 2.3Å AUTH K.H.NIELSEN,H.CHAMIEH,C.B.ANDERSEN,F.FREDSLUND,AUTH 2 K.HAMBORG,H.LE HIR,G.R.ANDERSENTITL MECHANISM OF ATP TURNOVER INHIBITION IN THE EJCREF RNA V. 15 67 2009REFN ISSN 1355-8382PMID 19033377DOI 10.1261/RNA.1283109 Variant Set Distributions Mapped Variants
General Structure Information 3hd6 RHCG crystal structure of the human rhesus glycoprotein rhcg 2.1Å AUTH F.GRUSWITZ,S.CHAUDHARY,J.D.HO,A.SCHLESSINGER,B.PEZESHKI,AUTH 2 C.M.HO,A.SALI,C.M.WESTHOFF,R.M.STROUDTITL FUNCTION OF HUMAN RH BASED ON STRUCTURE OF RHCG AT 2.1 A.REF PROC.NATL.ACAD.SCI.USA V. 107 9638 2010REFN ISSN 0027-8424PMID 20457942DOI 10.1073/PNAS.1003587107 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 1jkg NXT1 structural basis for the recognition of a nucleoporin fg- repeat by the ntf2-like domain of tap-p15 mrna nuclear export factor 1.9Å AUTH S.FRIBOURG,I.C.BRAUN,E.IZAURRALDE,E.CONTITITL STRUCTURAL BASIS FOR THE RECOGNITION OF ATITL 2 NUCLEOPORIN FG REPEAT BY THE NTF2-LIKE DOMAIN OFTITL 3 THE TAP/P15 MRNA NUCLEAR EXPORT FACTOR.REF MOL.CELL V. 8 645 […]
General Structure Information 2rb4 DDX25 crystal structure of the helicase domain of human ddx25 rna helicase 2.8Å AUTH P.SCHUTZ,T.KARLBERG,S.VAN DEN BERG,R.COLLINS,L.LEHTIO,AUTH 2 M.HOGBOM,L.HOLMBERG-SCHIAVONE,W.TEMPEL,H.W.PARK,AUTH 3 M.HAMMARSTROM,M.MOCHE,A.G.THORSELL,H.SCHULERTITL COMPARATIVE STRUCTURAL ANALYSIS OF HUMAN DEAD-BOX RNATITL 2 HELICASES.REF PLOS ONE V. 5 12791 2010REFN ESSN 1932-6203PMID 20941364DOI 10.1371/JOURNAL.PONE.0012791 Variant Set Distributions Mapped Variants