Assessment of Structural Intolerance and Durability
General Structure Information 1ukl SREBF2 crystal structure of importin-beta and srebp-2 complex 3.0Å AUTH S.J.LEE,T.SEKIMOTO,E.YAMASHITA,E.NAGOSHI,AUTH 2 A.NAKAGAWA,N.IMAMOTO,M.YOSHIMURA,H.SAKAI,K.T.CHONG,AUTH 3 T.TSUKIHARA,Y.YONEDATITL THE STRUCTURE OF IMPORTIN-BETA BOUND TO SREBP-2:TITL 2 NUCLEAR IMPORT OF A TRANSCRIPTION FACTORREF SCIENCE V. 302 1571 2003REFN ISSN 0036-8075PMID 14645851DOI 10.1126/SCIENCE.1088372 Variant Set Distributions Mapped Variants
General Structure Information 3vvw CALCOCO2 ndp52 in complex with lc3c 2.5Å AUTH N.V.MUHLINEN,M.AKUTSU,B.J.RAVENHILL,A.FOEGLEIN,S.BLOOR,AUTH 2 T.J.RUTHERFORD,S.M.FREUND,D.KOMANDER,F.RANDOWTITL LC3C, BOUND SELECTIVELY BY A NONCANONICAL LIR MOTIF INTITL 2 NDP52, IS REQUIRED FOR ANTIBACTERIAL AUTOPHAGYREF MOL.CELL V. 48 329 2012REFN ISSN 1097-2765PMID 23022382DOI 10.1016/J.MOLCEL.2012.08.024 Variant Set Distributions Mapped Variants
General Structure Information 3vvw CALCOCO2 ndp52 in complex with lc3c 2.5Å AUTH N.V.MUHLINEN,M.AKUTSU,B.J.RAVENHILL,A.FOEGLEIN,S.BLOOR,AUTH 2 T.J.RUTHERFORD,S.M.FREUND,D.KOMANDER,F.RANDOWTITL LC3C, BOUND SELECTIVELY BY A NONCANONICAL LIR MOTIF INTITL 2 NDP52, IS REQUIRED FOR ANTIBACTERIAL AUTOPHAGYREF MOL.CELL V. 48 329 2012REFN ISSN 1097-2765PMID 23022382DOI 10.1016/J.MOLCEL.2012.08.024 Variant Set Distributions Mapped Variants
General Structure Information 3vvw CALCOCO2 ndp52 in complex with lc3c 2.5Å AUTH N.V.MUHLINEN,M.AKUTSU,B.J.RAVENHILL,A.FOEGLEIN,S.BLOOR,AUTH 2 T.J.RUTHERFORD,S.M.FREUND,D.KOMANDER,F.RANDOWTITL LC3C, BOUND SELECTIVELY BY A NONCANONICAL LIR MOTIF INTITL 2 NDP52, IS REQUIRED FOR ANTIBACTERIAL AUTOPHAGYREF MOL.CELL V. 48 329 2012REFN ISSN 1097-2765PMID 23022382DOI 10.1016/J.MOLCEL.2012.08.024 Variant Set Distributions Mapped Variants
General Structure Information 4a60 FABP9 crystal structure of human testis-specific fatty acid binding protein 9 (fabp9) 1.53Å AUTH J.R.C.MUNIZ,W.KIYANI,L.SHRESTHA,D.S.FROESE,T.KROJER,AUTH 2 M.VOLLMAR,C.H.ARROWSMITH,A.M.EDWARDS,J.WEIGELT,C.BOUNTRA,AUTH 3 F.VON DELFT,W.W.YUETITL THE CRYSTAL STRUCTURE OF THE HUMAN FABP9AREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3nf1 KLC1 crystal structure of the tpr domain of kinesin light chain 1 2.8Å AUTH Y.TONG,W.TEMPEL,L.SHEN,Y.SHEN,L.NEDYALKOVA,C.H.ARROWSMITH,AUTH 2 A.M.EDWARDS,C.BOUNTRA,J.WEIGELT,A.BOCHKAREV,H.PARKTITL CRYSTAL STRUCTURE OF THE TPR DOMAIN OF KINESIN LIGHT CHAIN 1REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2l4r KCNH2 nmr solution structure of the n-terminal pas domain of herg -1.0Å AUTH Q.LI,S.GAYEN,A.S.CHEN,Q.HUANG,M.RAIDA,C.KANGTITL NMR SOLUTION STRUCTURE OF THE N-TERMINAL DOMAIN OF HERG ANDTITL 2 ITS INTERACTION WITH THE S4-S5 LINKER.REF BIOCHEM.BIOPHYS.RES.COMMUN. V. 403 126 2010REFN ISSN 0006-291XPMID 21055387DOI 10.1016/J.BBRC.2010.10.132 Variant Set Distributions Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2kmv ATP7A solution structure of the nucleotide binding domain of the human menkes protein in the atp-free form -1.0Å AUTH L.BANCI,I.BERTINI,F.CANTINI,S.INAGAKI,M.MIGLIARDI,AUTH 2 A.ROSATOTITL THE BINDING MODE OF ATP REVEALED BY THE SOLUTIONTITL 2 STRUCTURE OF THE N-DOMAIN OF HUMAN ATP7A.REF J.BIOL.CHEM. 2009REFN ESSN 1083-351XPMID 19917612DOI 10.1074/JBC.M109.054262 Variant Set Distributions Mapped Variants
General Structure Information 4hmy AP1B1 structural basis for recruitment and activation of the ap-1 clathrin adaptor complex by arf1 7.0Å AUTH X.REN,G.G.FARIAS,B.J.CANAGARAJAH,J.S.BONIFACINO,J.H.HURLEYTITL STRUCTURAL BASIS FOR RECRUITMENT AND ACTIVATION OF THE AP-1TITL 2 CLATHRIN ADAPTOR COMPLEX BY ARF1.REF CELL(CAMBRIDGE,MASS.) V. 152 755 2013REFN ISSN 0092-8674PMID 23415225DOI 10.1016/J.CELL.2012.12.042 Variant Set Distributions Ripley’s K Analysis Plots Variant Set […]
General Structure Information 4egx KIF1A crystal structure of kif1a cc1-fha tandem 2.51Å AUTH L.HUO,Y.YUE,J.REN,J.YU,J.LIU,Y.YU,F.YE,T.XU,M.ZHANG,W.FENGTITL THE CC1-FHA TANDEM AS A CENTRAL HUB FOR CONTROLLING THETITL 2 DIMERIZATION AND ACTIVATION OF KINESIN-3 KIF1AREF STRUCTURE V. 20 1550 2012REFN ISSN 0969-2126PMID 22863567DOI 10.1016/J.STR.2012.07.002 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants