General Structure Information
| PDB ID | 4hmy |
| HGNC Gene Label(s) | AP1B1 |
| Structure Name | structural basis for recruitment and activation of the ap-1 clathrin adaptor complex by arf1 |
| Resolution | 7.0Å |
| Reference | AUTH X.REN,G.G.FARIAS,B.J.CANAGARAJAH,J.S.BONIFACINO,J.H.HURLEYTITL STRUCTURAL BASIS FOR RECRUITMENT AND ACTIVATION OF THE AP-1TITL 2 CLATHRIN ADAPTOR COMPLEX BY ARF1.REF CELL(CAMBRIDGE,MASS.) V. 152 755 2013REFN ISSN 0092-8674PMID 23415225DOI 10.1016/J.CELL.2012.12.042 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 563 |
| Number Of SNVs | 88 |
| Number Of Permutations | 26293 |
| Optimal Distance Threshold | 31.0 |
| K Statistic | 0.375 |
| p-value | 0.199 |
COSMIC
| Number Of Residues | 563 |
| Number Of SNVs | 12 |
| Number Of Permutations | 12991 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.121 |
| p-value | 0.349 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 88 |
| Number Of COSMIC SNVs | 11 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.07 |
| p-value | 0.958 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
