Assessment of Structural Intolerance and Durability
General Structure Information 1jfi DR1 crystal structure of the nc2-tbp-dna ternary complex 2.62Å AUTH K.KAMADA,F.SHU,H.CHEN,S.MALIK,G.STELZER,R.G.ROEDER,AUTH 2 M.MEISTERERNST,S.K.BURLEYTITL CRYSTAL STRUCTURE OF NEGATIVE COFACTOR 2TITL 2 RECOGNIZING THE TBP-DNA TRANSCRIPTION COMPLEX.REF CELL(CAMBRIDGE,MASS.) V. 106 71 2001REFN ISSN 0092-8674PMID 11461703DOI 10.1016/S0092-8674(01)00417-2 Variant Set Distributions Mapped Variants
General Structure Information 1jfi DR1 crystal structure of the nc2-tbp-dna ternary complex 2.62Å AUTH K.KAMADA,F.SHU,H.CHEN,S.MALIK,G.STELZER,R.G.ROEDER,AUTH 2 M.MEISTERERNST,S.K.BURLEYTITL CRYSTAL STRUCTURE OF NEGATIVE COFACTOR 2TITL 2 RECOGNIZING THE TBP-DNA TRANSCRIPTION COMPLEX.REF CELL(CAMBRIDGE,MASS.) V. 106 71 2001REFN ISSN 0092-8674PMID 11461703DOI 10.1016/S0092-8674(01)00417-2 Variant Set Distributions Mapped Variants
General Structure Information 1jfi DR1 crystal structure of the nc2-tbp-dna ternary complex 2.62Å AUTH K.KAMADA,F.SHU,H.CHEN,S.MALIK,G.STELZER,R.G.ROEDER,AUTH 2 M.MEISTERERNST,S.K.BURLEYTITL CRYSTAL STRUCTURE OF NEGATIVE COFACTOR 2TITL 2 RECOGNIZING THE TBP-DNA TRANSCRIPTION COMPLEX.REF CELL(CAMBRIDGE,MASS.) V. 106 71 2001REFN ISSN 0092-8674PMID 11461703DOI 10.1016/S0092-8674(01)00417-2 Variant Set Distributions Mapped Variants
General Structure Information 1jfi DR1 crystal structure of the nc2-tbp-dna ternary complex 2.62Å AUTH K.KAMADA,F.SHU,H.CHEN,S.MALIK,G.STELZER,R.G.ROEDER,AUTH 2 M.MEISTERERNST,S.K.BURLEYTITL CRYSTAL STRUCTURE OF NEGATIVE COFACTOR 2TITL 2 RECOGNIZING THE TBP-DNA TRANSCRIPTION COMPLEX.REF CELL(CAMBRIDGE,MASS.) V. 106 71 2001REFN ISSN 0092-8674PMID 11461703DOI 10.1016/S0092-8674(01)00417-2 Variant Set Distributions Mapped Variants
General Structure Information 2ro1 TRIM28 nmr solution structures of human kap1 phd finger-bromodomain -1.0Å AUTH L.ZENG,K.L.YAP,A.V.IVANOV,X.WANG,S.MUJTABA,AUTH 2 O.PLOTNIKOVA,F.J.RAUSCHER,M.M.ZHOUTITL STRUCTURAL INSIGHTS INTO HUMAN KAP1 PHDTITL 2 FINGER-BROMODOMAIN AND ITS ROLE IN GENE SILENCINGREF NAT.STRUCT.MOL.BIOL. V. 15 626 2008REFN ISSN 1545-9993PMID 18488044DOI 10.1038/NSMB.1416 Variant Set Distributions Mapped Variants
General Structure Information 2md7 SP140 nmr structure of human sp140 phd finger trans conformer -1.0Å AUTH C.ZUCCHELLI,S.TAMBURRI,G.QUILICI,E.PALAGANO,A.BERARDI,AUTH 2 M.SAARE,P.PETERSON,A.BACHI,G.MUSCOTITL STRUCTURE OF HUMAN SP140 PHD FINGER: AN ATYPICAL FOLDTITL 2 INTERACTING WITH PIN1.REF FEBS J. V. 281 216 2014REFN ISSN 1742-464XPMID 24267382DOI 10.1111/FEBS.12588 Variant Set Distributions Mapped Variants
General Structure Information 3io2 EP300 crystal structure of the taz2 domain of p300 2.5Å AUTH M.MILLER,Z.DAUTER,S.CHERRY,J.E.TROPEA,A.WLODAWERTITL STRUCTURE OF THE TAZ2 DOMAIN OF P300: INSIGHTS INTO LIGANDTITL 2 BINDING.REF ACTA CRYSTALLOGR.,SECT.D V. 65 1301 2009REFN ISSN 0907-4449PMID 19966416DOI 10.1107/S0907444909040153 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 1k78 PAX5 pax5(1-149)+ets-1(331-440)+dna 2.25Å AUTH C.W.GARVIE,J.HAGMAN,C.WOLBERGERTITL STRUCTURAL STUDIES OF ETS-1/PAX5 COMPLEX FORMATIONTITL 2 ON DNA.REF MOL.CELL V. 8 1267 2001REFN ISSN 1097-2765PMID 11779502DOI 10.1016/S1097-2765(01)00410-5 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2aze E2F1 structure of the rb c-terminal domain bound to an e2f1-dp1 heterodimer 2.55Å AUTH S.M.RUBIN,A.L.GALL,N.ZHENG,N.P.PAVLETICHTITL STRUCTURE OF THE RB C-TERMINAL DOMAIN BOUND TOTITL 2 E2F1-DP1: A MECHANISM FOR PHOSPHORYLATION-INDUCEDTITL 3 E2F RELEASE.REF CELL(CAMBRIDGE,MASS.) V. 123 1093 2005REFN ISSN 0092-8674PMID 16360038DOI 10.1016/J.CELL.2005.09.044 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons […]
General Structure Information 4bs2 TARDBP nmr structure of human tdp-43 tandem rrms in complex with ug-rich rna -1.0Å AUTH P.J.LUKAVSKY,D.DAUJOTYTE,J.R.TOLLERVEY,J.ULE,C.STUANI,AUTH 2 E.BURATTI,F.E.BARALLE,F.F.DAMBERGER,F.H.T.ALLAINTITL MOLECULAR BASIS OF UG-RICH RNA RECOGNITION BY THE HUMANTITL 2 SPLICING FACTOR TDP-43REF NAT.STRUCT.MOL.BIOL. V. 20 1443 2013REFN ISSN 1545-9993PMID 24240615DOI 10.1038/NSMB.2698 Variant Set Distributions Mapped Variants