Assessment of Structural Intolerance and Durability
General Structure Information 2e5o TRIP4 solution structure of the trip_4c domain of target of activating signal cointegrator 1 -1.0Å AUTH W.DANG,Y.MUTO,M.INOUE,T.KIGAWA,M.SHIROUZU,T.TERADA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE TRIP_4C DOMAIN OF TARGETTITL 2 OF ACTIVATING SIGNAL COINTEGRATOR 1REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2e5o TRIP4 solution structure of the trip_4c domain of target of activating signal cointegrator 1 -1.0Å AUTH W.DANG,Y.MUTO,M.INOUE,T.KIGAWA,M.SHIROUZU,T.TERADA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE TRIP_4C DOMAIN OF TARGETTITL 2 OF ACTIVATING SIGNAL COINTEGRATOR 1REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2e5o TRIP4 solution structure of the trip_4c domain of target of activating signal cointegrator 1 -1.0Å AUTH W.DANG,Y.MUTO,M.INOUE,T.KIGAWA,M.SHIROUZU,T.TERADA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE TRIP_4C DOMAIN OF TARGETTITL 2 OF ACTIVATING SIGNAL COINTEGRATOR 1REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3l15 TEAD2 human tead2 transcriptional factor 2.0Å AUTH W.TIAN,J.YU,D.R.TOMCHICK,D.PAN,X.LUOTITL STRUCTURAL AND FUNCTIONAL ANALYSIS OF THE YAP-BINDINGTITL 2 DOMAIN OF HUMAN TEAD2.REF PROC.NATL.ACAD.SCI.USA V. 107 7293 2010REFN ISSN 0027-8424PMID 20368466DOI 10.1073/PNAS.1000293107 Variant Set Distributions Mapped Variants
General Structure Information 2lk2 TGIF1 solution nmr structure of homeobox domain (171-248) of human homeobox protein tgif1, northeast structural genomics consortium target hr4411b -1.0Å AUTH Y.YANG,T.A.RAMELOT,J.R.CORT,R.SHASTRY,C.CICCOSANTI,AUTH 2 K.HAMILTON,T.B.ACTON,R.XIAO,J.K.EVERETT,G.T.MONTELIONE,AUTH 3 M.A.KENNEDYTITL SOLUTION NMR STRUCTURE OF HOMEOBOX DOMAIN (171-248) OF HUMANTITL 2 HOMEOBOX PROTEIN TGIF1, NORTHEAST STRUCTURAL GENOMICSTITL 3 CONSORTIUM TARGET HR4411B.REF TO BE PUBLISHEDREFN Variant Set […]
General Structure Information 4b95 TCEB1 pvhl-elob-elob-elocc complex_(2s,4r)-1-(2-chlorophenyl)carbonyl-n-[ (4-chlorophenyl)methyl]-4-oxidanyl-pyrrolidine-2-carboxamide bound 2.8Å AUTH D.L.BUCKLEY,J.L.GUSTAFSON,I.VAN MOLLE,A.G.ROTH,H.S.TAE,AUTH 2 P.C.GAREISS,W.L.JORGENSEN,A.CIULLI,C.M.CREWSTITL SMALL-MOLECULE INHIBITORS OF THE INTERACTION BETWEEN THE E3TITL 2 LIGASE VHL AND HIF1ALPHAREF ANGEW.CHEM.INT.ED.ENGL. V. 51 11463 2012REFN ISSN 1433-7851PMID 23065727DOI 10.1002/ANIE.201206231 Variant Set Distributions Mapped Variants
General Structure Information 4b95 TCEB1 pvhl-elob-elob-elocc complex_(2s,4r)-1-(2-chlorophenyl)carbonyl-n-[ (4-chlorophenyl)methyl]-4-oxidanyl-pyrrolidine-2-carboxamide bound 2.8Å AUTH D.L.BUCKLEY,J.L.GUSTAFSON,I.VAN MOLLE,A.G.ROTH,H.S.TAE,AUTH 2 P.C.GAREISS,W.L.JORGENSEN,A.CIULLI,C.M.CREWSTITL SMALL-MOLECULE INHIBITORS OF THE INTERACTION BETWEEN THE E3TITL 2 LIGASE VHL AND HIF1ALPHAREF ANGEW.CHEM.INT.ED.ENGL. V. 51 11463 2012REFN ISSN 1433-7851PMID 23065727DOI 10.1002/ANIE.201206231 Variant Set Distributions Mapped Variants
General Structure Information 3dsh IRF5 crystal structure of dimeric interferon regulatory factor 5 (irf-5) transactivation domain 2.0Å AUTH W.CHEN,S.S.LAM,H.SRINATH,Z.JIANG,J.J.CORREIA,C.A.SCHIFFER,AUTH 2 K.A.FITZGERALD,K.LIN,W.E.ROYERTITL INSIGHTS INTO INTERFERON REGULATORY FACTOR ACTIVATION FROMTITL 2 THE CRYSTAL STRUCTURE OF DIMERIC IRF5.REF NAT.STRUCT.MOL.BIOL. V. 15 1213 2008REFN ISSN 1545-9993PMID 18836453DOI 10.1038/NSMB.1496 Variant Set Distributions Mapped Variants
General Structure Information 4hfx TCEB3 crystal structure of a transcription elongation factor b polypeptide 3 from homo sapiens, northeast structural genomics consortium target id hr4748b. 2.54Å AUTH J.SEETHARAMAN,M.SU,C CICCOSANTI,S SAHDEV,T.B.ACTON,R XIAO,AUTH 2 J.K EVERETT,G.T MONTELIONE,J.F.HUNT,L TONGTITL CRYSTAL STRUCTURE OF A TRANSCRIPTION ELONGATION FACTOR BTITL 2 POLYPEPTIDE 3 FROM HOMO SAPIENS, NORTHEAST STRUCTURALTITL 3 GENOMICS CONSORTIUM […]
General Structure Information 1jfi DR1 crystal structure of the nc2-tbp-dna ternary complex 2.62Å AUTH K.KAMADA,F.SHU,H.CHEN,S.MALIK,G.STELZER,R.G.ROEDER,AUTH 2 M.MEISTERERNST,S.K.BURLEYTITL CRYSTAL STRUCTURE OF NEGATIVE COFACTOR 2TITL 2 RECOGNIZING THE TBP-DNA TRANSCRIPTION COMPLEX.REF CELL(CAMBRIDGE,MASS.) V. 106 71 2001REFN ISSN 0092-8674PMID 11461703DOI 10.1016/S0092-8674(01)00417-2 Variant Set Distributions Mapped Variants