General Structure Information
| PDB ID | 4b95 |
| HGNC Gene Label(s) | TCEB1 |
| Structure Name | pvhl-elob-elob-elocc complex_(2s,4r)-1-(2-chlorophenyl)carbonyl-n-[ (4-chlorophenyl)methyl]-4-oxidanyl-pyrrolidine-2-carboxamide bound |
| Resolution | 2.8Å |
| Reference | AUTH D.L.BUCKLEY,J.L.GUSTAFSON,I.VAN MOLLE,A.G.ROTH,H.S.TAE,AUTH 2 P.C.GAREISS,W.L.JORGENSEN,A.CIULLI,C.M.CREWSTITL SMALL-MOLECULE INHIBITORS OF THE INTERACTION BETWEEN THE E3TITL 2 LIGASE VHL AND HIF1ALPHAREF ANGEW.CHEM.INT.ED.ENGL. V. 51 11463 2012REFN ISSN 1433-7851PMID 23065727DOI 10.1002/ANIE.201206231 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 86 |
| Number Of SNVs | 5 |
| Number Of Permutations | 263 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.2 |
| p-value | 0.494 |