Assessment of Structural Intolerance and Durability
General Structure Information 4hpl BCOR pcgf1 ub fold (rawul)/bcor pufd complex 2.0Å AUTH S.E.JUNCO,R.WANG,J.C.GAIPA,A.B.TAYLOR,V.SCHIRF,M.D.GEARHART,AUTH 2 V.J.BARDWELL,B.DEMELER,P.J.HART,C.A.KIMTITL STRUCTURE OF THE POLYCOMB GROUP PROTEIN PCGF1 IN COMPLEXTITL 2 WITH BCOR REVEALS BASIS FOR BINDING SELECTIVITY OF PCGFTITL 3 HOMOLOGS.REF STRUCTURE V. 21 665 2013REFN ISSN 0969-2126PMID 23523425DOI 10.1016/J.STR.2013.02.013 Variant Set Distributions Ripley’s K Analysis Plots Variant Set […]
General Structure Information 2da2 ZFHX3 solution structure of the second homeobox domain of at- binding transcription factor 1 (atbf1) -1.0Å AUTH S.OHNISHI,T.KIGAWA,N.TOCHIO,S.KOSHIBA,M.INOUE,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE SECOND HOMEOBOX DOMAINTITL 2 OF AT-BINDING TRANSCRIPTION FACTOR 1 (ATBF1)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2rfj BRDT crystal structure of the bromo domain 1 in human bromodomain containing protein, testis specific (brdt) 2.05Å AUTH P.FILIPPAKOPOULOS,S.PICAUD,M.MANGOS,T.KEATES,J.P.LAMBERT,AUTH 2 D.BARSYTE-LOVEJOY,I.FELLETAR,R.VOLKMER,S.MULLER,T.PAWSON,AUTH 3 A.C.GINGRAS,C.H.ARROWSMITH,S.KNAPPTITL HISTONE RECOGNITION AND LARGE-SCALE STRUCTURAL ANALYSIS OFTITL 2 THE HUMAN BROMODOMAIN FAMILY.REF CELL(CAMBRIDGE,MASS.) V. 149 214 2012REFN ISSN 0092-8674PMID 22464331DOI 10.1016/J.CELL.2012.02.013 Variant Set Distributions Ripley’s K Analysis Plots […]
General Structure Information 4mi0 EZH2 human enhancer of zeste (drosophila) homolog 2(ezh2) 2.0Å AUTH H.WU,H.ZENG,A.DONG,F.LI,H.HE,G.SENISTERRA,A.SEITOVA,S.DUAN,AUTH 2 P.J.BROWN,M.VEDADI,C.H.ARROWSMITH,M.SCHAPIRATITL STRUCTURE OF THE CATALYTIC DOMAIN OF EZH2 REVEALSTITL 2 CONFORMATIONAL PLASTICITY IN COFACTOR AND SUBSTRATE BINDINGTITL 3 SITES AND EXPLAINS ONCOGENIC MUTATIONS.REF PLOS ONE V. 8 83737 2013REFN ESSN 1932-6203PMID 24367611DOI 10.1371/JOURNAL.PONE.0083737 Variant Set Distributions Ripley’s K Analysis […]
General Structure Information 2prg NCOA1 ligand-binding domain of the human peroxisome proliferator activated receptor gamma 2.3Å AUTH R.T.NOLTE,G.B.WISELY,S.WESTIN,J.E.COBB,M.H.LAMBERT,AUTH 2 R.KUROKAWA,M.G.ROSENFELD,T.M.WILLSON,C.K.GLASS,AUTH 3 M.V.MILBURNTITL LIGAND BINDING AND CO-ACTIVATOR ASSEMBLY OF THETITL 2 PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR-GAMMA.REF NATURE V. 395 137 1998REFN ISSN 0028-0836PMID 9744270DOI 10.1038/25931 Variant Set Distributions Mapped Variants
General Structure Information 2rpp MBNL2 solution structure of tandem zinc finger domain 12 in muscleblind-like protein 2 -1.0Å AUTH F.HE,W.DANG,C.ABE,K.TSUDA,M.INOUE,S.WATANABE,AUTH 2 N.KOBAYASHI,T.KIGAWA,T.MATSUDA,T.YABUKI,M.AOKI,AUTH 3 E.SEKI,T.HARADA,Y.TOMABECHI,T.TERADA,M.SHIROUZU,AUTH 4 A.TANAKA,P.GUNTERT,Y.MUTO,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE RNA BINDING DOMAIN INTITL 2 THE HUMAN MUSCLEBLIND-LIKE PROTEIN 2REF PROTEIN SCI. V. 18 80 2009REFN ISSN 0961-8368PMID 19177353DOI 10.1002/PRO.17 Variant Set Distributions Mapped Variants
General Structure Information 2ytp ZNF484 solution structure of the c2h2 type zinc finger (region 687- 719) of human zinc finger protein 484 -1.0Å AUTH N.TOCHIO,T.TOMIZAWA,H.ABE,K.SAITO,H.LI,M.SATO,AUTH 2 S.KOSHIBA,N.KOBAYASHI,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE C2H2 TYPE ZINC FINGERTITL 2 (REGION 687-719) OF HUMAN ZINC FINGER PROTEIN 484REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 4h22 LRRFIP1 crystal structure of the dimeric coiled-coil domain of the cytosolic nucleic acid sensor lrrfip1 2.89Å AUTH J.B.NGUYEN,Y.MODISTITL CRYSTAL STRUCTURE OF THE DIMERIC COILED-COIL DOMAIN OF THETITL 2 CYTOSOLIC NUCLEIC ACID SENSOR LRRFIP1.REF J.STRUCT.BIOL. V. 181 82 2013REFN ISSN 1047-8477PMID 23099021DOI 10.1016/J.JSB.2012.10.006 Variant Set Distributions Mapped Variants
General Structure Information 4hpm BCORL1 pcgf1 ub fold (rawul)/bcorl1 pufd complex 1.85Å AUTH S.E.JUNCO,R.WANG,J.C.GAIPA,A.B.TAYLOR,V.SCHIRF,M.D.GEARHART,AUTH 2 V.J.BARDWELL,B.DEMELER,P.J.HART,C.A.KIMTITL STRUCTURE OF THE POLYCOMB GROUP PROTEIN PCGF1 IN COMPLEXTITL 2 WITH BCOR REVEALS BASIS FOR BINDING SELECTIVITY OF PCGFTITL 3 HOMOLOGS.REF STRUCTURE V. 21 665 2013REFN ISSN 0969-2126PMID 23523425DOI 10.1016/J.STR.2013.02.013 Variant Set Distributions Ripley’s K Analysis Plots Variant Set […]
General Structure Information 2emg ZNF484 solution structure of the c2h2 type zinc finger (region 463- 495) of human zinc finger protein 484 -1.0Å AUTH N.TOCHIO,T.TOMIZAWA,H.ABE,K.SAITO,H.LI,M.SATO,AUTH 2 S.KOSHIBA,N.KOBAYASHI,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE C2H2 TYPE ZINC FINGERTITL 2 (REGION 463-495) OF HUMAN ZINC FINGER PROTEIN 484REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants