Assessment of Structural Intolerance and Durability
General Structure Information 3s93 TDRD5 crystal structure of conserved motif in tdrd5 2.28Å AUTH X.CHAO,W.TEMPEL,C.BIAN,J.KANIA,A.K.WERNIMONT,C.BOUNTRA,AUTH 2 J.WEIGELT,C.H.ARROWSMITH,A.M.EDWARDS,J.MINTITL CRYSTAL STRUCTURE OF CONSERVED MOTIF IN TDRD5REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2eqo TRAF3IP1 solution structure of the stn_traf3ip1_nd domain of interleukin 13 receptor alpha 1-binding protein-1 [homo sapiens] -1.0Å AUTH W.DANG,Y.MUTO,M.INOUE,T.KIGAWA,M.SHIROUZU,T.TERADA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE STN_TRAF3IP1_ND DOMAINTITL 2 OF INTERLEUKIN 13 RECEPTOR ALPHA 1-BINDINGTITL 3 PROTEIN-1 [HOMO SAPIENS]REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2ecc HOMEZ solution structure of the second homeobox domain of human homeodomain leucine zipper-encoding gene (homez) -1.0Å AUTH S.OHNISHI,Y.O.KAMATARI,N.TOCHIO,N.KOBAYASHI,AUTH 2 S.KOSHIBA,M.INOUE,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE SECOND HOMEOBOX DOMAINTITL 2 OF HUMAN HOMEODOMAIN LEUCINE ZIPPER-ENCODING GENETITL 3 (HOMEZ)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3k2j PBRM1 crystal structure of the 3rd bromodomain of human poly-bromodomain containing protein 1 (pb1) 2.2Å AUTH P.FILIPPAKOPOULOS,S.PICAUD,T.KEATES,A.CHAIKUAD,A.C.W.PIKE,AUTH 2 T.KROJER,R.SETHI,F.VON DELFT,C.H.ARROWSMITH,A.EDWARDS,AUTH 3 J.WEIGELT,C.BOUNTRA,S.KNAPPTITL CRYSTAL STRUCTURE OF THE 3RD BROMODOMAIN OF HUMANTITL 2 POLY-BROMODOMAIN CONTAINING PROTEIN 1 (PB1)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3ljw PBRM1 crystal structure of the second bromodomain of human polybromo 1.5Å AUTH Z.CHARLOP-POWERS,L.ZENG,Q.ZHANG,M.M.ZHOUTITL STRUCTURAL INSIGHTS INTO SELECTIVE HISTONE H3 RECOGNITIONTITL 2 BY THE HUMAN POLYBROMO BROMODOMAIN 2.REF CELL RES. V. 20 529 2010REFN ISSN 1001-0602PMID 20368734DOI 10.1038/CR.2010.43 Variant Set Distributions Mapped Variants
General Structure Information 3ob9 MSL3 structure of the human msl3 chromo-barrel domain at 2.5 angstrom resolution 2.5Å AUTH S.A.MOORE,Y.FERHATOGLUTITL STRUCTURE OF THE HUMAN MSL3 CHROMO-BARREL DOMAIN AT 2.5TITL 2 ANGSTROM RESOLUTIONREF J.BIOL.CHEM. 2010REFN ESSN 1083-351X Variant Set Distributions Mapped Variants
General Structure Information 2l76 NFATC2IP solution nmr structure of human nfatc2ip ubiquitin-like domain, nfatc2ip_244_338, nesg target ht65a/ocsp target hs00387_244_338/sgc- toronto -1.0Å AUTH R.DOHERTY,B.WU,A.YEE,A.LEMAK,S.HOULISTON,C.FARES,S.SRISALAM,AUTH 2 C.BULTER,A.M.EDWARDS,J.WEIGELT,S.DHE-PAGANON,C.H.ARROWSMITHTITL HUMAN NFATC2IP UBIQUITIN-LIKE DOMAINSREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2fmm C11orf30 crystal structure of emsy-hp1 complex 1.8Å AUTH Y.HUANG,M.P.MYERS,R.M.XUTITL CRYSTAL STRUCTURE OF THE HP1-EMSY COMPLEX REVEALS AN UNUSUALTITL 2 MODE OF HP1 BINDING.REF STRUCTURE V. 14 703 2006REFN ISSN 0969-2126PMID 16615912DOI 10.1016/J.STR.2006.01.007 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3cuq VPS36 integrated structural and functional model of the human escrt-ii complex 2.61Å AUTH Y.J.IM,J.H.HURLEYTITL INTEGRATED STRUCTURAL MODEL AND MEMBRANE TARGETING MECHANISMTITL 2 OF THE HUMAN ESCRT-II COMPLEXREF DEV.CELL V. 14 902 2008REFN ISSN 1534-5807PMID 18539118DOI 10.1016/J.DEVCEL.2008.04.004 Variant Set Distributions Mapped Variants
General Structure Information 3s8p SUV420H1 crystal structure of the set domain of human histone-lysine n- methyltransferase suv420h1 in complex with s-adenosyl-l-methionine 1.85Å AUTH H.WU,A.SIARHEYEVA,H.ZENG,R.LAM,A.DONG,X.H.WU,Y.LI,AUTH 2 M.SCHAPIRA,M.VEDADI,J.MINTITL CRYSTAL STRUCTURES OF THE HUMAN HISTONE H4K20TITL 2 METHYLTRANSFERASES SUV420H1 AND SUV420H2.REF FEBS LETT. V. 587 3859 2013REFN ISSN 0014-5793PMID 24396869 Variant Set Distributions Ripley’s K Analysis Plots Variant […]